Search Results - "Patel, Yashomati M"

Regulation of myosin light chain kinase during insulin-stimulated glucose uptake in 3T3-L1 adipocytes by Woody, Shelly, Stall, Richard, Ramos, Joseph, Patel, Yashomati M

“…Myosin II (MyoII) is required for insulin-responsive glucose transporter 4 (GLUT4)-mediated glucose uptake in 3T3-L1 adipocytes. Our previous studies have…”
Get full text

Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: a mechanism for impaired cellular proliferation by HARMON, Anne W, PATEL, Yashomati M

“…Certain flavonoids inhibit glucose uptake in cultured cells. In this report, we show that the grapefruit flava-none naringenin inhibited insulin-stimulated…”
Get full text

Regulation of myosin IIA and filamentous actin during insulin-stimulated glucose uptake in 3T3-L1 adipocytes by Stall, Richard, Ramos, Joseph, Kent Fulcher, F., Patel, Yashomati M.

“…Insulin stimulated glucose uptake requires the colocalization of myosin IIA (MyoIIA) and the insulin-responsive glucose transporter 4 (GLUT4) at the plasma…”
Get full text

Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes by Paul, David S, Harmon, Anne W, Winston, Courtney P, Patel, Yashomati M

“…Calpains are a family of non-lysosomal cysteine proteases. Recent studies have identified a member of the calpain family of proteases, calpain 10, as a…”
Get full text

A naringenin–tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells by Hatkevich, Talia, Ramos, Joseph, Santos-Sanchez, Idalys, Patel, Yashomati M.

“…Since over 60% of breast cancers are estrogen receptor positive (ER+), many therapies have targeted the ER. The ER is activated by both estrogen binding and…”
Get full text

MEK inhibitors impair insulin-stimulated glucose uptake in 3T3-L1 adipocytes by Harmon, Anne W, Paul, David S, Patel, Yashomati M

“…In 3T3-L1 adipocytes, insulin activates three major signaling cascades, the phosphoinositide 3-kinase (PI3K) pathway, the Cbl pathway, and the…”
Get more information

Calpain facilitates actin reorganization during glucose-stimulated insulin secretion by Turner, Mark D., Fulcher, F. Kent, Jones, Cristina V., Smith, Bethany T., Aganna, Ebun, Partridge, Christopher J., Hitman, Graham A., Clark, Anne, Patel, Yashomati M.

“…Calpain-10 (CAPN10) has been identified as a diabetes susceptibility gene. Previous studies have shown that alterations in calpain activity alter both glucose…”
Get full text

Role of Calpain in Adipocyte Differentiation by Patel, Yashomati M., Lane, M. Daniel

“…Evidence is presented that the calcium-activated protease, calpain, is required for differentiation of 3T3-L1 preadipocytes into adipocytes induced by…”
Get full text

Inhibition of the MAPK pathway alone is insufficient to account for all of the cytotoxic effects of naringenin in MCF-7 breast cancer cells by Eanes, Lauren, Patel, Yashomati M.

“…Estrogen receptor (ER) antagonists such as tamoxifen (Tam) have been used successfully to treat ER+ breast cancers for more than 30 years. Unfortunately, long…”
Get full text

Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes by Walton, Felecia S, Harmon, Anne W, Paul, David S, Drobná, Zuzana, Patel, Yashomati M, Styblo, Miroslav

“…Chronic exposures to inorganic arsenic (iAs) have been associated with increased incidence of noninsulin (type-2)-dependent diabetes mellitus. Although…”
Get full text

Naringenin inhibits phosphoinositide 3-kinase activity and glucose uptake in 3T3-L1 adipocytes by Harmon, Anne W, Patel, Yashomati M

“…Previous studies have shown that flavonoids inhibit glucose uptake in cultured cells. In this report, we show that the grapefruit flavanone naringenin…”
Get full text

Mitotic Clonal Expansion during Preadipocyte Differentiation: Calpain-mediated Turnover of p27 by Patel, Yashomati M., Lane, M.Daniel

“…Evidence is presented that calpain, a calcium-activated protease, degrades the cyclin-dependent kinase inhibitor, p27, during the mitotic clonal expansion…”
Get full text

Dual role for myosin II in GLUT4-mediated glucose uptake in 3T3-L1 adipocytes by Fulcher, F. Kent, Smith, Bethany T., Russ, Misty, Patel, Yashomati M.

“…Insulin-stimulated glucose uptake requires the activation of several signaling pathways to mediate the translocation and fusion of GLUT4 vesicles to the plasma…”
Get full text

Genistein inhibits CCAAT/enhancer-binding protein beta (C/EBPbeta) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression by Harmon, Anne W, Patel, Yashomati M, Harp, Joyce B

“…The tyrosine kinase inhibitor genistein inhibits 3T3-L1 adipogenesis when present during the first 72 h of differentiation. In this report, we investigated the…”
Get full text

A novel role for myosin II in insulin-stimulated glucose uptake in 3T3-L1 adipocytes by Steimle, Paul A., Kent Fulcher, F., Patel, Yashomati M.

“…Insulin-stimulated glucose uptake requires the activation of several signaling pathways to mediate the translocation and fusion of GLUT4 vesicles from an…”
Get full text

GLUT4 expression in 3T3-L1 adipocytes is repressed by proteasome inhibition, but not by inhibition of calpains by Cooke, David W., Patel, Yashomati M.

“…Because of recent studies showing linkage of type 2 diabetes with the calpain 10 gene, we investigated the ability of calpains to regulate GLUT4 expression in…”
Get full text

Rb regulates C/EBPbeta-DNA-binding activity during 3T3-L1 adipogenesis by Cole, Kathryn A, Harmon, Anne W, Harp, Joyce B, Patel, Yashomati M

“…Two pathways are initiated upon 3T3-L1 preadipocyte differentiation: the reentry of cells into the cell cycle and the initiation of a cascade of…”
Get more information

Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes by Friedman, J.E, Yun, J.S, Patel, Y.M, McGrane, M.M, Hanson, R.W

“…The hormonal regulation of transcription of the phosphoenolpyruvate carboxykinase (GTP) (4.1.1.32) (PEPCK) gene during diabetes was studied using transgenic…”
Get full text

An analysis of regulatory elements in the phosphoenolpyruvate carboxykinase (GTP) gene which are responsible for its tissue-specific expression and metabolic control in transgenic mice by PATEL, V. M, YUN, J. S, JINSONG LIU, MCGRANE, M. M, HANSON, R. W

“…Sequences in the gene for P-enolpyruvate carboxykinase (PEPCK) which are responsible for its complex pattern of transcriptional control were determined using…”
Get full text

Metabolic control of gene expression: in vivo studies with transgenic mice by McGrane, M M, Yun, J S, Patel, Y M, Hanson, R W

“…Transgenic animals provide a comprehensive model for investigating genes encoding inducible enzymes involved in metabolism, since the molecular mechanisms…”
Get more information