Search Results - "Patel, Tapan P."

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death by Volpicelli-Daley, Laura A., Luk, Kelvin C., Patel, Tapan P., Tanik, Selcuk A., Riddle, Dawn M., Stieber, Anna, Meaney, David F., Trojanowski, John Q., Lee, Virginia M.-Y.

“…Inclusions composed of α-synuclein (α-syn), i.e., Lewy bodies (LBs) and Lewy neurites (LNs), define synucleinopathies including Parkinson's disease (PD) and…”
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Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging by Patel, Tapan P., Man, Karen, Firestein, Bonnie L., Meaney, David F.

“…•We present an open-source software for semi-automated analysis of fluorescent calcium imaging.•FluoroSNNAP, Fluorescence Single Neuron and Network Analysis…”
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Aflibercept more effectively weans patients with neovascular age-related macular degeneration off therapy compared with bevacizumab by Cao, Xuan, Sanchez, Jaron Castillo, Patel, Tapan P, Yang, Zhiyong, Guo, Chuanyu, Malik, Danyal, Sopeyin, Anuoluwapo, Montaner, Silvia, Sodhi, Akrit

“…BACKGROUNDStudies assessing the efficacy of therapies for neovascular age-related macular degeneration (nvAMD) have demonstrated that aflibercept may have a…”
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Deep learning for automated detection of neovascular leakage on ultra-widefield fluorescein angiography in diabetic retinopathy by Zhao, Peter Y., Bommakanti, Nikhil, Yu, Gina, Aaberg, Michael T., Patel, Tapan P., Paulus, Yannis M.

“…Diabetic retinopathy is a leading cause of blindness in working-age adults worldwide. Neovascular leakage on fluorescein angiography indicates progression to…”
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Aqueous proteins help predict the response of patients with neovascular age-related macular degeneration to anti-VEGF therapy by Cao, Xuan, Sanchez, Jaron Castillo, Dinabandhu, Aumreetam, Guo, Chuanyu, Patel, Tapan P, Yang, Zhiyong, Hu, Ming-Wen, Chen, Lijun, Wang, Yuefan, Malik, Danyal, Jee, Kathleen, Daoud, Yassine J, Handa, James T, Zhang, Hui, Qian, Jiang, Montaner, Silvia, Sodhi, Akrit

“…BackgroundTo reduce the treatment burden for patients with neovascular age-related macular degeneration (nvAMD), emerging therapies targeting vascular…”
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An open-source toolbox for automated phenotyping of mice in behavioral tasks by Patel, Tapan P, Gullotti, David M, Hernandez, Pepe, O'Brien, W Timothy, Capehart, Bruce P, Morrison, 3rd, Barclay, Bass, Cameron, Eberwine, James E, Abel, Ted, Meaney, David F

“…Classifying behavior patterns in mouse models of neurological, psychiatric and neurodevelopmental disorders is critical for understanding disease causality and…”
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Smartphone-based fundus photography for screening of plus-disease retinopathy of prematurity by Patel, Tapan P., Aaberg, Michael T., Paulus, Yannis M., Lieu, Philip, Dedania, Vaidehi S., Qian, Cynthia X., Besirli, Cagri G., Margolis, Todd, Fletcher, Daniel A., Kim, Tyson N.

“…Background Inadequate screening of treatment-warranted retinopathy of prematurity (ROP) can lead to devastating visual outcomes. Especially in resource-poor…”
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Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases by Ong, Sally S, Patel, Tapan P, Singh, Mandeep S

“…Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the…”
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Spatial Characteristics of Peripheral Visual Islands in Retinitis Pigmentosa by Patel, Tapan P, Vongsachang, Hursuong, Schilling, Andrew, Kong, Xiangrong, Singh, Mandeep S

“…Retinitis pigmentosa (RP) is typified by progressive peripheral visual field (pVF) loss in patterns that can vary between individuals. Greater understanding of…”
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Quantification of Retinal Nonperfusion and Neovascularization With Ultrawidefield Fluorescein Angiography in Patients With Diabetes and Associated Characteristics of Advanced Disease by Yu, Gina, Aaberg, Michael T, Patel, Tapan P, Iyengar, Rahul S, Powell, Corey, Tran, Annie, Miranda, Caitlin, Young, Emma, Demetriou, Katarina, Devisetty, Laxmi, Paulus, Yannis M

“…Quantification of nonperfusion (NP) and neovascularization (NV) in diabetic retinopathy (DR) may identify better biomarkers of disease progression. To identify…”
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Retinal neovascularization as self-organized criticality on ultra-widefield fluorescein angiography imaging of diabetic retinopathy by Young, Benjamin K., Bommakanti, Nikhil, Yu, Gina, Patel, Tapan P., Azzouz, Lyna, Powell, Corey, Paulus, Yannis M.

“…Background/Objectives Do the distributions of surface area of non-perfusion (NP) and neovascularization (NV) on ultra-widefield fluorescein angiography (UWF…”
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Antimicrobial guide to posterior segment infections by Patel, Tapan P., Zacks, David N., Dedania, Vaidehi S.

“…Purpose This review article is meant to serve as a reference guide and to assist the treating physician in making an appropriate selection and duration of an…”
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Single-neuron NMDA receptor phenotype influences neuronal rewiring and reintegration following traumatic injury by Patel, Tapan P, Ventre, Scott C, Geddes-Klein, Donna, Singh, Pallab K, Meaney, David F

“…Alterations in the activity of neural circuits are a common consequence of traumatic brain injury (TBI), but the relationship between single-neuron properties…”
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Frequency of Urgent or Emergent Vitreoretinal Surgical Procedures in the United States During the COVID-19 Pandemic by Breazzano, Mark P, Nair, Archana A, Arevalo, J Fernando, Barakat, Mark R, Berrocal, Audina M, Chang, Jonathan S, Chen, Andrew, Eliott, Dean, Garg, Sunir J, Ghadiali, Quraish, Gong, Dan, Grewal, Dilraj S, Handa, James T, Henderson, Matthew, Leiderman, Yannek I, Leng, Theodore, Mannina, Amar, Mendel, Thomas A, Mustafi, Debarshi, de Koo, Lisa C Olmos, Patel, Shriji N, Patel, Tapan P, Prenner, Jonathan, Richards, Paige, Singh, Rishi P, Wykoff, Charles C, Yannuzzi, Nicolas A, Yu, Hannah, Modi, Yasha S, Chang, Stanley

“…The American Academy of Ophthalmology (AAO) indicated that urgent or emergent vitreoretinal surgical procedures should continue during the coronavirus disease…”
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Novel Image-Based Analysis for Reduction of Clinician-Dependent Variability in Measurement of the Corneal Ulcer Size by Patel, Tapan P, Prajna, N Venkatesh, Farsiu, Sina, Valikodath, Nita G, Niziol, Leslie M, Dudeja, Lakshey, Kim, Kyeong Hwan, Woodward, Maria A

“…PURPOSE:To assess variability in corneal ulcer measurements between ophthalmologists and reduce clinician-dependent variability using semiautomated…”
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Choroidal Neovascularization Associated with Pentosan Polysulfate Toxicity by Mishra, Kapil, Patel, Tapan P, Singh, Mandeep S

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Alterations in Hippocampal Network Activity after In Vitro Traumatic Brain Injury by Kang, Woo Hyeun, Cao, Wenzhe, Graudejus, Oliver, Patel, Tapan P, Wagner, Sigurd, Meaney, David F, Morrison, 3rd, Barclay

“…Traumatic brain injury (TBI) alters function and behavior, which can be characterized by changes in electrophysiological function in vitro. A common cognitive…”
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Antagonism of purinergic signalling improves recovery from traumatic brain injury by CHOO, Anthony M, MILLER, William J, HAYDON, Philip G, MEANEY, David F, CHEN, Yung-Chia, NIBLEY, Philip, PATEL, Tapan P, GOLETIANI, Cezar, MORRISON, Barclay, KUTZING, Melinda K, FIRESTEIN, Bonnie L, SUL, Jai-Yoon

“…The recent public awareness of the incidence and possible long-term consequences of traumatic brain injury only heightens the need to develop effective…”
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Splenial Restricted Diffusion as MRI Correlate of Diaschisis in a Blind Infant With Unilateral Posterior Cerebral Artery Stroke by Eton, Emily A., Patel, Tapan P., Srinivasan, Ashok, Moritani, Toshio, Trobe, Jonathan D.

“…A 3-month-old male infant appeared on multiple clinical examinations to have acutely developed bilateral retrogeniculate blindness. Electroencephalography…”
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Isolated Primary Blast Inhibits Long-Term Potentiation in Organotypic Hippocampal Slice Cultures by Vogel, 3rd, Edward W, Effgen, Gwen B, Patel, Tapan P, Meaney, David F, Bass, Cameron R Dale, Morrison, 3rd, Barclay

“…Over the last 13 years, traumatic brain injury (TBI) has affected over 230,000 U.S. service members through the conflicts in Iraq and Afghanistan, mostly as a…”
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