Search Results - "Patel, Shaun R."

Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer's Disease by Ning, Shen, Jorfi, Mehdi, Patel, Shaun R, Kim, Doo Yeon, Tanzi, Rudolph E

“…Alzheimer's disease (AD) is the most common cause of dementia in the elderly, clinically defined by progressive cognitive decline and pathologically, by brain…”
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Sharp Wave Ripples during Visual Exploration in the Primate Hippocampus by Leonard, Timothy K, Mikkila, Jonathan M, Eskandar, Emad N, Gerrard, Jason L, Kaping, Daniel, Patel, Shaun R, Womelsdorf, Thilo, Hoffman, Kari L

“…Hippocampal sharp-wave ripples (SWRs) are highly synchronous oscillatory field potentials that are thought to facilitate memory consolidation. SWRs typically…”
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Frequency-Dependent Representation of Reinforcement-Related Information in the Human Medial and Lateral Prefrontal Cortex by Smith, Elliot H, Banks, Garrett P, Mikell, Charles B, Cash, Syndey S, Patel, Shaun R, Eskandar, Emad N, Sheth, Sameer A

“…The feedback-related negativity (FRN) is a commonly observed potential in scalp electroencephalography (EEG) studies related to the valence of feedback about a…”
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An open source 3-d printed modular micro-drive system for acute neurophysiology by Patel, Shaun R, Ghose, Kaushik, Eskandar, Emad N

“…Current, commercial, electrode micro-drives that allow independent positioning of multiple electrodes are expensive. Custom designed solutions developed by…”
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Precision electronic medicine in the brain by Patel, Shaun R., Lieber, Charles M.

“…Periodically throughout history developments from adjacent fields of science and technology reach a tipping point where together they produce unparalleled…”
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Intermittent subthalamic nucleus deep brain stimulation induces risk-aversive behavior in human subjects by Patel, Shaun R, Herrington, Todd M, Sheth, Sameer A, Mian, Matthew, Bick, Sarah K, Yang, Jimmy C, Flaherty, Alice W, Frank, Michael J, Widge, Alik S, Dougherty, Darin, Eskandar, Emad N

“…The subthalamic nucleus (STN) is a small almond-shaped subcortical structure classically known for its role in motor inhibition through the indirect pathway…”
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Modulations in Oscillatory Activity of Globus Pallidus Internus Neurons During a Directed Hand Movement Task-A Primary Mechanism for Motor Planning by Saxena, Shreya, Sarma, Sridevi V, Patel, Shaun R, Santaniello, Sabato, Eskandar, Emad N, Gale, John T

“…Globus pallidus internus (GPi) neurons in the basal ganglia are traditionally thought to play a significant role in the promotion and suppression of movement…”
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Human dorsal anterior cingulate cortex neurons mediate ongoing behavioural adaptation by Sheth, Sameer A., Mian, Matthew K., Patel, Shaun R., Asaad, Wael F., Williams, Ziv M., Dougherty, Darin D., Bush, George, Eskandar, Emad N.

“…Functional imaging, single-cell recording and targeted surgical lesions were used in human patients undergoing cingulotomy to show that the dorsal anterior…”
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Dynamics of Ketamine-induced Loss and Return of Consciousness across Primate Neocortex by Ballesteros, Jesus J., Huang, Pamela, Patel, Shaun R., Eskandar, Emad N., Ishizawa, Yumiko

“…BACKGROUND:Ketamine is a noncompetitive N-methyl-D-aspartate antagonist and is known for unique electrophysiologic profiles in electroencephalography. However,…”
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Author Correction: Precision electronic medicine in the brain by Patel, Shaun R., Lieber, Charles M.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Leveraging Nonhuman Primate Multisensory Neurons and Circuits in Assessing Consciousness Theory by Noel, Jean-Paul, Ishizawa, Yumiko, Patel, Shaun R, Eskandar, Emad N, Wallace, Mark T

“…Both the global neuronal workspace (GNW) and integrated information theory (IIT) posit that highly complex and interconnected networks engender perceptual…”
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Caudate stimulation enhances learning by Bick, Sarah K, Patel, Shaun R, Katnani, Husam A, Peled, Noam, Widge, Alik, Cash, Sydney S, Eskandar, Emad N

“…Neuromodulation is a promising treatment modality for disorders of learning and memory, offering the possibility of precise alteration of disordered neural…”
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Dynamics of Propofol-Induced Loss of Consciousness Across Primate Neocortex by Ishizawa, Yumiko, Ahmed, Omar J, Patel, Shaun R, Gale, John T, Sierra-Mercado, Demetrio, Brown, Emery N, Eskandar, Emad N

“…The precise neural mechanisms underlying transitions between consciousness and anesthetic-induced unconsciousness remain unclear. Here, we studied…”
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Dynamics of recovery from anaesthesia-induced unconsciousness across primate neocortex by Patel, Shaun R, Ballesteros, Jesus J, Ahmed, Omar J, Huang, Pamela, Briscoe, Jessica, Eskandar, Emad N, Ishizawa, Yumiko

“…How the brain recovers from general anaesthesia is poorly understood. Neurocognitive problems during anaesthesia recovery are associated with an increase in…”
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Lesion Procedures in Psychiatric Neurosurgery by Patel, Shaun R, Aronson, Joshua P, Sheth, Sameer A, Eskandar, Emad N

“…Objective Lesion procedures for psychiatric indications have a history that spans more than a century. This review provides a brief history of psychiatric…”
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Encoding of rules by neurons in the human dorsolateral prefrontal cortex by Mian, Matthew K, Sheth, Sameer A, Patel, Shaun R, Spiliopoulos, Konstantinos, Eskandar, Emad N, Williams, Ziv M

“…We use rules to extend learned behavior beyond specific instances to general scenarios. The prefrontal cortex (PFC) is thought to play an important role in…”
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Temporally Coordinated Deep Brain Stimulation in the Dorsal and Ventral Striatum Synergistically Enhances Associative Learning by Katnani, Husam A., Patel, Shaun R., Kwon, Churl-Su, Abdel-Aziz, Samer, Gale, John T., Eskandar, Emad N.

“…The primate brain has the remarkable ability of mapping sensory stimuli into motor behaviors that can lead to positive outcomes. We have previously shown that…”
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Single-neuron responses in the human nucleus accumbens during a financial decision-making task by Patel, Shaun R, Sheth, Sameer A, Mian, Matthew K, Gale, John T, Greenberg, Benjamin D, Dougherty, Darin D, Eskandar, Emad N

“…Linking values to actions and evaluating expectations relative to outcomes are both central to reinforcement learning and are thought to underlie financial…”
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Studying task-related activity of individual neurons in the human brain by Patel, Shaun R, Sheth, Sameer A, Martinez-Rubio, Clarissa, Mian, Matthew K, Asaad, Wael F, Gerrard, Jason L, Kwon, Churl-Su, Dougherty, Darin D, Flaherty, Alice W, Greenberg, Benjamin D, Gale, John T, Williams, Ziv M, Eskandar, Emad N

“…Single-neuronal studies remain the gold standard for studying brain function. Here we describe a protocol for studying task-related single-neuronal activity in…”
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Epiquinamide: A Poison That Wasn’t from a Frog That Was by Fitch, Richard W, Sturgeon, Gordon D, Patel, Shaun R, Spande, Thomas F, Garraffo, H. Martin, Daly, John W, Blaauw, Richard H

“…In 2003, we reported the isolation, structure elucidation, and pharmacology of epiquinamide (1), a novel alkaloid isolated from an Ecuadoran poison frog,…”
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