Search Results - "Patel, Nibedita"

Tissue-location-specific transcription programs drive tumor dependencies in colon cancer by Yang, Lijing, Tu, Lei, Bisht, Shilpa, Mao, Yiqing, Petkovich, Daniel, Thursby, Sara-Jayne, Liang, Jinxiao, Patel, Nibedita, Yen, Ray-Whay Chiu, Largent, Tina, Zahnow, Cynthia, Brock, Malcolm, Gabrielson, Kathy, Salimian, Kevan J., Baylin, Stephen B., Easwaran, Hariharan

“…Cancers of the same tissue-type but in anatomically distinct locations exhibit different molecular dependencies for tumorigenesis. Proximal and distal colon…”
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miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin by Patel, Nibedita, Garikapati, Koteswara Rao, Pandita, Raj K., Singh, Dharmendra Kumar, Pandita, Tej K., Bhadra, Utpal, Bhadra, Manika Pal

“…The B-lymphoma Moloney murine leukemia virus insertion region-1 protein (BMI1) acts as an oncogene in various cancers, including breast cancer. Recent evidence…”
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Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug by Patel, Nibedita, Garikapati, Koteswara Rao, Makani, Venkata Krishna Kanth, Nair, Ayikkara Drishya, Vangara, Namratha, Bhadra, Utpal, Pal Bhadra, Manika

“…Polycomb group (PcG) proteinB lymphoma Mo-MLV insertion region 1 homolog (BMI1) is a transcriptional repressor that plays an important role in human…”
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Erratum: miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin by Patel, Nibedita, Garikapati, Koteswara Rao, Pandita, Raj K., Singh, Dharmendra Kumar, Pandita, Tej K., Bhadra, Utpal, Bhadra, Manika Pal

“…A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper…”
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Novel anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates modulate the expression of p53-MYCN associated micro RNAs in neuroblastoma cells and cause cell cycle arrest and apoptosis by Ramaiah, M. Janaki, Pushpavalli, Sreerangam N.C.V.L., Lavanya, A., Bhadra, Kaustav, Haritha, V., Patel, Nibedita, Tamboli, Jaki R., Kamal, Ahmed, Bhadra, Utpal, Pal-Bhadra, Manika

“…Compounds activate p53 dependent tumor suppressor pathway. In this study anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates activates tumor suppressors (p53,…”
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Kruppel‐like factor 6 and miR‐223 signaling axis regulates macrophage‐mediated inflammation by Kim, Gun-Dong, Ng, Hang Pong, Patel, Nibedita, Mahabeleshwar, Ganapati H.

“…ABSTRACT Macrophage‐mediated inflammation is an explicitly robust biologic response that plays a critical role in maintaining tissue homeostasis by eliminating…”
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Down-regulation of BORIS/CTCFL efficiently regulates cancer stemness and metastasis in MYCN amplified neuroblastoma cell line by modulating Wnt/β-catenin signaling pathway by Garikapati, Koteswara Rao, Patel, Nibedita, Makani, Venkata Krishna Kanth, Cilamkoti, Priyanka, Bhadra, Utpal, Bhadra, Manika Pal

“…BORIS/CTCFL is a vital nucleotide binding protein expressed during embryogenesis and gametogenesis. BORIS/CTCFL is the paralogue of transcriptional repressor…”
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miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1 by Patel, Nibedita, Garikapati, Koteswara Rao, Ramaiah, M. Janaki, Polavarapu, Kavi Kishor, Bhadra, Utpal, Bhadra, Manika Pal

“…miRNAs are small non-coding RNA molecules that regulate post-transcriptional gene expression. Here we have made an endeavor to search whether any miRNAs are…”
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miRNA let-7a inhibits invasion, migration, anchorage-independent growth by suppressing EZH2 and promotes mesenchymal to epithelial transition in MDAMB-231 by Patel, Nibedita, Garikapati, Koteswara Rao, Makani, Venkata Krishna Kanth, Pal, Shreya, Vangara, Namratha, Bhadra, Manika Pal

“…Enhancer of zeste homolog 2 (EZH2) is a transcriptional repressor belonging to the polycomb group protein family (PRC) and is frequently linked with aggressive…”
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Downregulation of BORIS/CTCFL leads to ROS‐dependent cellular senescence and drug sensitivity in MYCN‐amplified neuroblastoma by Rao, Garikapati Koteswara, Makani, Venkata Krishna Kanth, Mendonza, Jolly Janette, Edathara, Prajitha Mohandas, Patel, Nibedita, Ramakrishna, Maresha, Cilamkoti, Priyanka, Chiring Phukon, Jayashree, Jose, Jedy, Bhadra, Utpal, Bhadra, Manika Pal

“…Brother of Regulator of Imprinted Sites (BORIS) or CCCTC‐binding factor like (CTCFL) is a nucleotide‐binding protein, aberrantly expressed in various…”
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Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition by Padmaja, Pannala, Koteswara Rao, Garikapati, Indrasena, Adisherla, Subba Reddy, Basireddy V, Patel, Nibedita, Shaik, Anver Basha, Reddy, Narayana, Dubey, Pramod K, Bhadra, Manika Pal

“…A series of novel pyrano[3,2-c]carbazole derivatives have been synthesized by a simple one-pot, three component reaction of aromatic aldehydes,…”
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Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition by Patel, Nibedita, Garikapati, Koteswara Rao, Makani, Venkata Krishna Kanth, Nair, Ayikkara Drishya, Vangara, Namratha, Bhadra, Utpal, Pal Bhadra, Manika

“…Polycomb group (PcG) proteinB lymphoma Mo-MLV insertion region 1 homolog (BMI1) is a transcriptional repressor that plays an important role in human…”
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Abstract B016: Aberrant age-related methylation leads to tumor predisposition in colorectal organoids by Petkovich, Daniel A., Powers, Rachael, Tao, Yong, Kang, Byunghak, Patel, Nibedita, Gabrielson, Kathy, Cabo, Rafael de, Baylin, Stephen B., Easwaran, Hariharan P.

“…Abstract Aging is one of the greatest risk factors for cancers, and epigenetic changes involving DNA methylation show close similarities during age-related…”
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Synthesis and mechanistic aspects of 2-anilinonicotinyl-pyrazolo[1,5-a]pyrimidine conjugates that regulate cell proliferation in MCF-7 cells via estrogen signaling by Kamal, Ahmed, Faazil, Shaikh, Hussaini, S.M. Ali, Ramaiah, M. Janaki, Balakrishna, M., Patel, Nibedita, Pushpavalli, S.N.C.V.L., Pal-Bhadra, Manika

“…[Display omitted] A series of anilinonicotinyl linked pyrazolo[1,5-a]pyrimidine conjugates (6a–x) were synthesized and evaluated for their antiproliferative…”
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Synthesis and study of benzothiazole conjugates in the control of cell proliferation by modulating Ras/MEK/ERK-dependent pathway in MCF-7 cells by Kamal, Ahmed, Faazil, Shaikh, Ramaiah, M. Janaki, Ashraf, Md, Balakrishna, M., Pushpavalli, S.N.C.V.L., Patel, Nibedita, Pal-Bhadra, Manika

“…Conjugate (4o) cause G2/M cell cycle arrest and inhibit cell growth by Ras dependent pathway involving key downstream targets that help in cell proliferation…”
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