Search Results - "Patel, Navin B"

Microwave produced 8-methyl-1,2,4,8-tetraazaspiro[4.5]dec-2-en-3-amine derivatives: their in vitro and in silico analysis by Patel, Parth P., Patel, Navin B., Tople, Manesh S., Patel, Vatsal M., Ahmed, Iqrar, Patel, Harun

“…Compound 1 is formed by a microwave-assisted multicomponent reaction of 1-methylpiperidin-4-one, 2-amino-4-methoxy-6-methyl-1,3,5-triazine, and…”
Get full text

Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles by Patel, Navin B., Khan, Imran H., Rajani, Smita D.

“…The triazole analogs were obtained via. multistep synthesis sequence beginning with ethyl nicotinoate 3 which on treatment with hydrazine hydrate yields…”
Get full text

Editorial: Discovery and Development of Drugs for Neglected Diseases: Chagas Disease, Human African Trypanosomiasis, and Leishmaniasis by Rivera, Gildardo, Patel, Navin B., Bandyopadhyay, Debasish

Get full text

Design & synthesis of hybrid pharmacophore of β-lactam, 1,8-naphthyridine, and secondary amines; Discover their in vitro antimicrobial, anticancer properties & DFT and ADMET prediction studies by Pandya, Keyur M., Battula, Satyanarayana, Kumar, K. A. Aravinda, Patel, Rajesh J., Patel, Navin B.

“…An efficient synthetic strategy was developed for the synthesis of hybrid pharmacophores; encompass the merging of β -lactams, 1,8-naphthyridine and secondary…”
Get full text

Synthesis, In silico Molecular Docking and Pharmacokinetic Studies, In vitro Antimycobacterial and Antimicrobial Studies of New Imidozolones Clubbed with Thiazolidinedione by Khan, Imran H, Patel, Navin B, Patel, Vatsal M

“…A series of (E)-5-(4-((Z)-4-substitutedbenzylidene-2-thienylmethylene-5-oxo- 2-phenyl-4,5-dihydro-1H-imidazol-1-yl) benzylidene)thiazolidine-2,4-diones were…”
Get more information

Benzopyrazine-Based Small Molecule Inhibitors As Trypanocidal and Leishmanicidal Agents: Green Synthesis, In Vitro , and In Silico Evaluations by Rock, Jonathan, Garcia, Daniel, Espino, Omar, Shetu, Shaila A, Chan-Bacab, Manuel J, Moo-Puc, Rosa, Patel, Navin B, Rivera, Gildardo, Bandyopadhyay, Debasish

“…World Health Organization (WHO) identified twenty tropical disease categories as neglected tropical diseases (NTDs). Chagas' disease (also known as American…”
Get full text

Heat detection techniques in cattle and buffalo by Rao, Thakur Krishna Shankar, Kumar, Niranjan, Kumar, Pankaj, Chaurasia, Shailendra, Patel, Navin B

“…Proper heat detection to achieve appropriate timing of insemination is the biggest restriction in attaining high conception rate in dairy herd. The estrus…”
Get full text

Synthesis, biological evaluation, and In silico molecular docking of N‐(4‐(4‐substitutedphenyl)‐6‐(substituted aryl) pyrimidin‐2‐yl)‐2‐(2‐isonicotinoyl hydrazinyl) acetamide by Soni, Hetal I., Patel, Navin B., Ahmad, Iqrar, Patel, Harun, Rivera, Gildardo

“…Isonicotinohydrazide is the first‐line medication in the prevention and treatment of tuberculosis. Antitubercular, antibacterial, antifungal, antiviral,…”
Get full text

Design & Synthesis of InCl3 Catalyzed Novel Pyrazole Conjugates with 2°-Amines; Discover Their in Vitro Antimicrobial & DFT Studies by Pandya, Keyur M., Battula, Satyanarayana, Patel, Navin B.

“…A mild and efficient protocol was developed for the synthesis of pyrazole and 2 ° -amine hybrid conjugates through an InCl 3 Ugi four-component reaction…”
Get full text

Synthesis of novel 5-alkyl/aryl/heteroaryl substituted diethyl 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates by aziridine ring expansion of 2-[(aziridin-1-yl)-1-alkyl/aryl/heteroaryl-methylene]malonic acid diethyl esters by More, Satish S, Mohan, T Krishna, Kumar, Y Sateesh, Kumar, U K Syam, Patel, Navin B

“…A novel synthetic methodology has been developed for the synthesis of diethyl 5-alkyl/aryl/heteroaryl substituted 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates…”
Get full text

Microwave irradiation for the synthesis of quinoline scaffolds: a review by Tople, Manesh S., Patel, Navin B., Patel, Parth P.

“…This review article provides a detailed overview of the microwave-assisted synthesis of quinoline and its derivatives. Traditional synthetic techniques require…”
Get full text

N-Mannich bases of benzimidazole as a potent antitubercular and antiprotozoal agents: Their synthesis and computational studies by Patel, Vatsal M., Patel, Navin B., Chan-Bacab, Manuel J., Rivera, Gildardo

“…This article dealing with the microwave assisted synthesis of N-Mannich bases of pyridine clubbed with two different benzimidazole cores with their micromolar…”
Get full text

Synthesis, biological evaluation and molecular dynamics studies of 1,2,4-triazole clubbed Mannich bases by Patel, Vatsal M., Patel, Navin B., Chan-Bacab, Manuel J., Rivera, Gildardo

“…A series of newer analogous of triazole were synthesized by introduction of N-Mannich reaction using conventional as well as microwave synthetic route and…”
Get full text

Synthesis of Benzothiazole and Pyrimidine Based Fused Derivatives and Their Biological Evaluation by Patel, Navin B., Maisuria, Pratik N., Gujarati, Akash V., Patel, Divyesh K.

“…In the present study a series of ethyl 4-(substituted)-2-methyl-4 H -benzo[4,5]thiazolo[3,2- a ]pyrimidine-3-carboxylate and ethyl…”
Get full text

Synthesis and evaluation of antibacterial and antifungal activities of 4-thiazolidinones and 2-azetidinones derivatives from chalcone by Patel, Navin B., Patel, Minesh D.

“…( E )-3-(thiophen-2-yl)-1-(4-methylphenyl)-prop-2-en-1-one 1 was obtained from the reaction of thiophene-2-aldehyde with p-methyl acetophenone. The treatment…”
Get full text

New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: their synthesis and biological evaluation by Patel, Navin B, Purohit, Amit C, Rajani, Dhanji P, Moo-Puc, Rosa, Rivera, Gildardo

“…A novel series of 5-(2-benzylsulfanyl-pyridin-3-yl)-2-(substituted)-sulfanyl-1,3,4-oxadiazoles 6a-j were synthesized from key intermediate…”
Get full text

Synthesis and biological evaluation of coumarin based isoxazoles, pyrimidinthiones and pyrimidin-2-ones by Patel, Divyesh, Kumari, Premlata, Patel, Navin B.

“…The titled compounds (6′a–k), (7′a–k) and (8′a–k) were synthesized from chalcones (5a–k) having coumarin moiety. Cyclization of chalcones (5a–k) with hydroxyl…”
Get full text

In vitro and in vivo assessment of newer quinoxaline–oxadiazole hybrids as antimicrobial and antiprotozoal agents by Patel, Navin B., Patel, Jignesh N., Purohit, Amit C., Patel, Vatsal M., Rajani, Dhanji P., Moo-Puc, Rosa, Lopez-Cedillo, Julio Cesar, Nogueda-Torres, Benjamin, Rivera, Gildardo

“…•Series of N-(substituted-phenyl)-2-[5-(quinoxalin-2-yloxymethyl)-[1,3,4] oxadiazol-2-ylsulfanyl]-acetamides synthesised.•In vitro antimicrobial and…”
Get full text

Synthesis and biological evaluation of coumarin clubbed thiazines scaffolds as antimicrobial and antioxidant by Chauhan, Nilesh B., Patel, Navin B., Patel, Vatsal M., Mistry, Bhupendra M.

“…A new series of 4-methyl-6-nitro-2-oxo-2 H -chroman-7yl-2-(4-(4-fluorophenyl)-6-phenyl-2 H -1,3-thiazin-2-yl-amino)acetates 5a – j were synthesized from…”
Get full text

Synthesis and antimicrobial activity of new pyridine derivatives-I by Patel, Navin B., Agravat, Suresh N., Shaikh, Faiyazalam M.

“…2-Amino substituted benzothiazoles 2a–l and 2-chloropyridine-3-carboxylic acid 3 were used to prepare 2-[ N…”
Get full text