Search Results - "Patel, Kaushik"

Cardiorenal Syndrome: The Role of Neural Connections Between the Heart and the Kidneys by Patel, Kaushik P., Katsurada, Kenichi, Zheng, Hong

“…The maintenance of cardiovascular homeostasis is highly dependent on tightly controlled interactions between the heart and the kidneys. Therefore, it is not…”
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Calcineurin Controls Hypothalamic NMDA Receptor Activity and Sympathetic Outflow by Patel, Kaushik P., Zheng, Hong

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The role of afferent renal nerves in regulating sympathetic outflow via central nervous system mechanisms by Katsurada, Kenichi, Patel, Kaushik P

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Metal Matrix Composites Fabricated by Stir Casting Process-A Review by Sankhla, Arvind, Patel, Kaushik M

“…This paper presents a detailed review of the fabrication of metal matrix composites through the stir-casting process and its processing issues. Metal matrix…”
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Dendritic Peptide Release Mediates Interpopulation Crosstalk between Neurosecretory and Preautonomic Networks by Son, Sook Jin, Filosa, Jessica A., Potapenko, Evgeniy S., Biancardi, Vinicia C., Zheng, Hong, Patel, Kaushik P., Tobin, Vicky A., Ludwig, Mike, Stern, Javier E.

“…Although communication between neurons is considered a function of the synapse, neurons also release neurotransmitter from their dendrites. We found that…”
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Renal denervation improves sodium excretion in rats with chronic heart failure: effects on expression of renal ENaC and AQP2 by Zheng, Hong, Liu, Xuefei, Katsurada, Kenichi, Patel, Kaushik P

“…Previously we have shown that increased expression of renal epithelial sodium channels (ENaC) may contribute to the renal sodium and water retention observed…”
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Astrocytes Contribute to Angiotensin II Stimulation of Hypothalamic Neuronal Activity and Sympathetic Outflow by Stern, Javier E, Son, Sookjin, Biancardi, Vinicia C, Zheng, Hong, Sharma, Neeru, Patel, Kaushik P

“…Angiotensin II (AngII) is a key neuropeptide that acting within the brain hypothalamic paraventricular nucleus regulates neurohumoral outflow to the…”
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Critical review of literature on Lean Six Sigma methodology by Patel, Anand S, Patel, Kaushik M

“…Purpose This paper aims to develop an initial understanding of the Lean Six Sigma methodology since its inception and examine the few Lean Six Sigma dimensions…”
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Integration of renal sensory afferents at the level of the paraventricular nucleus dictating sympathetic outflow by Zheng, Hong, Patel, Kaushik P

“…Abstract The sympathetic nervous system has been identified as a major contributor to the pathophysiology of chronic heart failure (CHF) and other diseases…”
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Enhanced Expression and Function of Renal SGLT2 (Sodium-Glucose Cotransporter 2) in Heart Failure: Role of Renal Nerves by Katsurada, Kenichi, Nandi, Shyam S., Sharma, Neeru M., Patel, Kaushik P.

“…Recent clinical studies demonstrate that SGLT2 (sodium-glucose cotransporter 2) inhibitors ameliorate heart failure (HF). The present study was conducted to…”
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MMP9 inhibition increases autophagic flux in chronic heart failure by Nandi, Shyam S, Katsurada, Kenichi, Sharma, Neeru M, Anderson, Daniel R, Mahata, Sushil K, Patel, Kaushik P

“…Increased matrix metalloprotease 9 (MMP9) after myocardial infarction (MI) exacerbates ischemia-induced chronic heart failure (CHF). Autophagy is…”
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Renal denervation based on experimental rationale by Katsurada, Kenichi, Ogoyama, Yukako, Imai, Yasushi, Patel, Kaushik P, Kario, Kazuomi

“…Excessive activation of the sympathetic nervous system is one of the pathophysiological hallmarks of hypertension and heart failure. Within the central nervous…”
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A Critical Role for the Paraventricular Nucleus of the Hypothalamus in the Regulation of the Volume Reflex in Normal and Various Cardiovascular Disease States by Zheng, Hong, Katsurada, Kenichi, Nandi, Shyam, Li, Yifan, Patel, Kaushik P.

“…Purpose of Review This review focuses on studies implicating forebrain neural pathways and neuromodulator systems, particularly, the nitric oxide system within…”
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Enhanced activation of RVLM-projecting PVN neurons in rats with chronic heart failure by Xu, Bo, Zheng, Hong, Patel, Kaushik P

“…Previous studies have indicated that there is increased activation of the paraventricular nucleus (PVN) in rats with chronic heart failure (CHF); however, it…”
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Activation of afferent renal nerves modulates RVLM-projecting PVN neurons by Xu, Bo, Zheng, Hong, Liu, Xuefei, Patel, Kaushik P

“…Renal denervation for the treatment of hypertension has proven to be successful; however, the underlying mechanism/s are not entirely clear. To determine if…”
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Decreased Mitochondrial Unfolded Protein Response (UPRmt) in HFpEF by Nandi, Shyam S., Maresh, Gerald M., Patel, Kaushik P.

“…Mitochondrial dysfunction is a feature of heart failure with preserve ejection fraction (HFpEF). Central infusion of Ang II causes sympatho‐excitation and…”
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Role of Renal Sympathetic Nerves in GLP-1 (Glucagon-Like Peptide-1) Receptor Agonist Exendin-4-Mediated Diuresis and Natriuresis in Diet-Induced Obese Rats by Liu, Xuefei, Patel, Kaushik P, Zheng, Hong

“…Background The gut-derived hormone GLP-1 (glucagon-like peptide-1) exerts beneficial effects against established risk factors for chronic kidney disease. GLP-1…”
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Central neural control of sympathetic nerve activity in heart failure following exercise training by Patel, Kaushik P, Zheng, Hong

“…Typical characteristics of chronic congestive heart failure (HF) are increased sympathetic drive, altered autonomic reflexes, and altered body fluid…”
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Does glucagon-like peptide-1 induce diuresis and natriuresis by modulating afferent renal nerve activity? by Katsurada, Kenichi, Nandi, Shyam S, Sharma, Neeru M, Zheng, Hong, Liu, Xuefei, Patel, Kaushik P

“…Glucagon-like peptide-1 (GLP-1), an incretin hormone, has diuretic and natriuretic effects. The present study was designed to explore the possible underlying…”
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Downregulation of neuronal nitric oxide synthase (nNOS) within the paraventricular nucleus in Ins2Akita-type-1 diabetic mice contributes to sympatho-excitation by Patel, Tapan A., Gao, Lie, Boomer, Shane H., Liu, Xuefei, Patel, Kaushik P., Zheng, Hong

“…Activation of both renin-angiotensin system (RAS) and the sympathetic system is the primary etiologic event in developing cardiovascular complications in…”
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