Search Results - "Patel, Jigisha A."

Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension by Shen, Lei, Patel, Jigisha A., Norel, Xavier, Moledina, Shahin, Whittle, Brendan J., von Kessler, Kirby, Sista, Prakash, Clapp, Lucie H.

“…[Display omitted] Beraprost is a prostacyclin analogue and IP receptor agonist which is approved to treat pulmonary arterial hypertension (PAH) in Asia. The…”
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Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells by Patel, Jigisha A, Shen, Lei, Hall, Susan M, Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J, Moledina, Shahin, Silverstein, Adam M, Whittle, Brendan J, Clapp, Lucie H

“…Prostacyclins are extensively used to treat pulmonary arterial hypertension (PAH), a life-threatening disease involving the progressive thickening of small…”
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Prostacyclin mimetics inhibit DRP1-mediated pro-proliferative mitochondrial fragmentation in pulmonary arterial hypertension by Abu-Hanna, Jeries, Anastasakis, Evangelos, Patel, Jigisha A., Eddama, Mohammad Mahmoud Rajab, Denton, Christopher P., Taanman, Jan-Willem, Abraham, David, Clapp, Lucie H.

“…Pulmonary arterial hypertension (PAH) is a rare cardiopulmonary disorder, involving the remodelling of the small pulmonary arteries. Underlying this…”
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Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature by Abu-Hanna, Jeries, Patel, Jigisha A, Anastasakis, Evangelos, Cohen, Richard, Clapp, Lucie H, Loizidou, Marilena, Eddama, Mohammad M. R

“…Abstract Histone 3 lysine 27 (H3K27) demethylation constitutes an important epigenetic mechanism of gene activation. It is mediated by the Jumonji C…”
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