Search Results - "Patel, Himika"

Evaluation of [11C]TAZA for amyloid β plaque imaging in postmortem human Alzheimer's disease brain region and whole body distribution in rodent PET/CT by Pan, Min-Liang, Mukherjee, Meenakshi T., Patel, Himika H., Patel, Bhavin, Constantinescu, Cristian C., Mirbolooki, M. Reza, Liang, Christopher, Mukherjee, Jogeshwar

“…ABSTRACT Objective: Alzheimer's disease (AD) is a neurodegenerative disease characterized by Aβ plaques in the brain. The aim of this study was to evaluate the…”
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18F-Fluorodeoxyglycosylamines: Maillard reaction of 18F-fluorodeoxyglucose with biological amines by Baranwal, Aparna, Patel, Himika H., Mukherjee, Jogeshwar

“…The Maillard reaction of sugars and amines resulting in the formation of glycosylamines and Amadori products is of biological significance, for drug delivery,…”
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Biomarker Analyses in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Eculizumab: Results from the Phase III Randomized COMMODORE 2 Trial by Lundberg, Pontus, de la Iglesia, Silvia, Kelly, Richard J, Kulasekararaj, Austin, Nishimura, Jun-Ichi, Risitano, Antonio M, Roeth, Alexander, Buatois, Simon, Chebon, Sammy, Patel, Himika, Kiialainen, Anna

“…Introduction PNH is a hematopoietic stem cell disorder characterized by hemolytic anemia, hemoglobinuria, and increased risk of thromboembolic events, and is…”
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Trial in Progress: The Randomized, Double-Blind, Placebo-Controlled Phase Ib CROSSWALK-a Trial Evaluating the Safety of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOEs) in Patients with Sickle Cell Disease (SCD) by Bartolucci, Pablo, Ataga, Kenneth I., Callaghan, Michael U., De Franceschi, Lucia, Minniti, Caterina, Alexandrou, Ari, Imbs, Diane-Charlotte, Fox, Richard, Patel, Himika, Sostelly, Alexandre, Schimmel, Jonathan

“…Background SCD is a group of autosomal recessive red blood cell (RBC) disorders caused by a single point mutation in the β-globin gene, resulting in the…”
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Phase 3 randomized COMMODORE 1 trial: Crovalimab versus eculizumab in complement inhibitor‐experienced patients with paroxysmal nocturnal hemoglobinuria by Scheinberg, Phillip, Clé, Diego Villa, Kim, Jin Seok, Nur, Erfan, Yenerel, Mustafa N., Barcellini, Wilma, Bonito, Debora, Giai, Valentina, Hus, Marek, Lee, YooJin, Lekue, Cristina Barrenetxea, Panse, Jens, Ueda, Yasutaka, Buatois, Simon, Gentile, Brittany, Kiialainen, Anna, Patel, Himika, Sreckovic, Sasha, Uguen, Marianne, Edwards, John, Nagy, Zsolt, Kulasekararaj, Austin G.

“…Crovalimab, a novel C5 inhibitor, allows for low‐volume, every‐4‐ week, subcutaneous self‐administration. COMMODORE 1 (NCT04432584) is a phase 3, global,…”
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IMvigor130 clinical trial in patients (pts) with metastatic urothelial carcinoma (mUC): Analysis of upper tract (UT) and lower tract (LT) subgroups by De Santis, Maria, Grande, Enrique, Mencinger, Marina, Li, Jian-Ri, Puente, Javier, Izumi, Kouji, Lee, Jae-Lyun, Kose, Fatih, Antonyan, Igor, Ding, Beiying, Patel, Himika, Davis, Ian D.

“…Abstract only 551 Background: IMvigor130 demonstrated a statistically significant improvement in PFS in pts receiving atezolizumab (atezo; anti–PD-L1) +…”
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Crovalimab treatment in patients with paroxysmal nocturnal haemoglobinuria: Long‐term results from the phase I/II COMPOSER trial by Röth, Alexander, Ichikawa, Satoshi, Ito, Yoshikazu, Kim, Jin Seok, Nagy, Zsolt, Obara, Naoshi, Panse, Jens, Schrezenmeier, Hubert, Sica, Simona, Soret, Juliette, Usuki, Kensuke, Yoon, Sung‐Soo, Balachandran, Nadiesh, Buri, Muriel, Lundberg, Pontus, Patel, Himika, Shinomiya, Kenji, Sostelly, Alexandre, Nishimura, Jun‐ichi

“…Objectives This study reports long‐term outcomes from the open‐label extension (OLE) period of the Phase I/II COMPOSER trial (NCT03157635) that evaluated…”
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18 F‐Fluorodeoxyglycosylamines: Maillard reaction of 18 F‐fluorodeoxyglucose with biological amines by Baranwal, Aparna, Patel, Himika H., Mukherjee, Jogeshwar

“…The Maillard reaction of sugars and amines resulting in the formation of glycosylamines and Amadori products is of biological significance, for drug delivery,…”
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Evaluation of [ 11 C ]TAZA for amyloid β plaque imaging in postmortem human A lzheimer's disease brain region and whole body distribution in rodent PET/CT by Pan, Min‐Liang, Mukherjee, Meenakshi T., Patel, Himika H., Patel, Bhavin, Constantinescu, Cristian C., Mirbolooki, M. Reza, Liang, Christopher, Mukherjee, Jogeshwar

“…ABSTRACT Objective: Alzheimer's disease (AD) is a neurodegenerative disease characterized by Aβ plaques in the brain. The aim of this study was to evaluate the…”
Get full text

Evaluation of [11C]TAZA for amyloid [beta] plaque imaging in postmortem human Alzheimer's disease brain region and whole body distribution in rodent PET/CT by Pan, Min-Liang, Mukherjee, Meenakshi T, Patel, Himika H, Patel, Bhavin, Constantinescu, Cristian C, Mirbolooki, M Reza, Liang, Christopher, Mukherjee, Jogeshwar

“…Objective: Alzheimer's disease (AD) is a neurodegenerative disease characterized by A[beta] plaques in the brain. The aim of this study was to evaluate the…”
Get full text