Search Results - "Patel, Hailee"
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1
Matrix stiffness drives drop like nuclear deformation and lamin A/C tension-dependent YAP nuclear localization
Published in Nature communications (22-11-2024)“…Extracellular matrix (ECM) stiffness influences cancer cell fate by altering gene expression. Previous studies suggest that stiffness-induced nuclear…”
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Journal Article -
2
Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities
Published in iScience (21-10-2022)“…Two prominent frontline breast cancer (BC) chemotherapies commonly used in combination, doxorubicin (DOX) and docetaxel (TAX), are associated with long-lasting…”
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Journal Article -
3
Effect of type I interferon on engineered pediatric skeletal muscle: a promising model for juvenile dermatomyositis
Published in Rheumatology (Oxford, England) (04-01-2024)“…To investigate pathogenic mechanisms underlying JDM, we defined the effect of type I IFN, IFN-α and IFN-β, on pediatric skeletal muscle function and expression…”
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Journal Article -
4
Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB
Published in Proceedings of the National Academy of Sciences - PNAS (30-07-2024)“…Transceptors, solute transporters that facilitate intracellular entry of molecules and also initiate intracellular signaling events, have been primarily…”
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Journal Article -
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Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells
Published in Journal of tissue engineering and regenerative medicine (01-02-2022)“…Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily targeting the joints. Autoreactive immune cells involved in RA affect other tissues,…”
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Journal Article -
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Characterization of Maturation of Tissue Engineered Skeletal Muscle Bundles in Rheumatoid Arthritis
Published 01-01-2019“…Rheumatoid Arthritis (RA) is a chronic inflammatory auto-immune disease typically involving the joints, mainly the diarthrodial joint and generally starts…”
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Dissertation