Search Results - "Patel, Gaurang C"

Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma by Patel, Gaurang C, Millar, J Cameron, Clark, Abbot F

“…Glucocorticoid (GC)-induced ocular hypertension (GC-OHT) is a serious side effect of prolonged GC therapy that can lead to glaucoma and permanent vision loss…”
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TGFβ2 Induces the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells Through the Smad and Non-Smad Dependent Pathways by Montecchi-Palmer, Michela, Bermudez, Jaclyn Y, Webber, Hannah C, Patel, Gaurang C, Clark, Abbot F, Mao, Weiming

“…Increased intraocular pressure results from increased aqueous humor (AH) outflow resistance at the trabecular meshwork (TM) due to pathologic changes including…”
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HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork by Bermudez, Jaclyn Y, Webber, Hannah C, Patel, Gaurang C, Liu, Xiangyang, Cheng, Yi-Qiang, Clark, Abbot F, Mao, Weiming

“…Elevated intraocular pressure (IOP) in primary open-angle glaucoma (POAG) results from glaucomatous damage to the trabecular meshwork (TM). The…”
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Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration by Patel, Gaurang C, Phan, Tien N, Maddineni, Prabhavathi, Kasetti, Ramesh B, Millar, J Cameron, Clark, Abbot F, Zode, Gulab S

“…Glucocorticoid (GC)-induced ocular hypertension (OHT) is a serious adverse effect of prolonged GC therapy that can lead to iatrogenic glaucoma and permanent…”
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Establishment of a conditionally immortalized mouse optic nerve astrocyte line by Liu, Yang, Patel, Gaurang C., Mao, Weiming, Clark, Abbot F.

“…Optic nerve astrocytes play a major role in axonal degeneration and regeneration. Astrocyte lines are an important tool to elucidate the responsible cellular…”
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Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension in mice by Patel, Gaurang C., Liu, Yang, Millar, J. Cameron, Clark, Abbot F.

“…Prolonged glucocorticoid (GC) therapy can cause GC-induced ocular hypertension (OHT), which if left untreated progresses to iatrogenic glaucoma and permanent…”
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Anterior chamber perfusion versus posterior chamber perfusion does not influence measurement of aqueous outflow facility in living mice by constant flow infusion by Lopez, Navita N., Patel, Gaurang C., Raychaudhuri, Urmimala, Aryal, Subhash, Phan, Tien N., Clark, Abbot F., Millar, J. Cameron

“…Mice are now routinely utilized in studies of aqueous humor outflow dynamics. In particular, conventional aqueous outflow facility (C) is routinely measured…”
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Dexamethasone-Induced Ocular Hypertension in Mice by Patel, Gaurang C, Phan, Tien N, Maddineni, Prabhavathi, Kasetti, Ramesh B, Millar, J. Cameron, Clark, Abbot F, Zode, Gulab S

“…Glucocorticoid (GC)-induced ocular hypertension (OHT) is a serious adverse effect of prolonged GC therapy that can lead to iatrogenic glaucoma and permanent…”
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Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms by McDowell, Colleen M, Kizhatil, Krishnakumar, Elliott, Michael H, Overby, Darryl R, van Batenburg-Sherwood, Joseph, Millar, J Cameron, Kuehn, Markus H, Zode, Gulab, Acott, Ted S, Anderson, Michael G, Bhattacharya, Sanjoy K, Bertrand, Jacques A, Borras, Terete, Bovenkamp, Diane E, Cheng, Lin, Danias, John, De Ieso, Michael Lucio, Du, Yiqin, Faralli, Jennifer A, Fuchshofer, Rudolf, Ganapathy, Preethi S, Gong, Haiyan, Herberg, Samuel, Hernandez, Humberto, Humphries, Peter, John, Simon W M, Kaufman, Paul L, Keller, Kate E, Kelley, Mary J, Kelly, Ruth A, Krizaj, David, Kumar, Ajay, Leonard, Brian C, Lieberman, Raquel L, Liton, Paloma, Liu, Yutao, Liu, Katy C, Lopez, Navita N, Mao, Weiming, Mavlyutov, Timur, McDonnell, Fiona, McLellan, Gillian J, Mzyk, Philip, Nartey, Andrews, Pasquale, Louis R, Patel, Gaurang C, Pattabiraman, Padmanabhan P, Peters, Donna M, Raghunathan, Vijaykrishna, Rao, Ponugoti Vasantha, Rayana, Naga, Raychaudhuri, Urmimala, Reina-Torres, Ester, Ren, Ruiyi, Rhee, Douglas, Chowdhury, Uttio Roy, Samples, John R, Samples, E Griffen, Sharif, Najam, Schuman, Joel S, Sheffield, Val C, Stevenson, Cooper H, Soundararajan, Avinash, Subramanian, Preeti, Sugali, Chenna Kesavulu, Sun, Yang, Toris, Carol B, Torrejon, Karen Y, Vahabikashi, Amir, Vranka, Janice A, Wang, Ting, Willoughby, Colin E, Xin, Chen, Yun, Hongmin, Zhang, Hao F, Fautsch, Michael P, Tamm, Ernst R, Clark, Abbot F, Ethier, C Ross, Stamer, W Daniel

“…Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms…”
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ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma by Praveen, Kavita, Patel, Gaurang C., Gurski, Lauren, Ayer, Ariane H., Persaud, Trikaladarshi, Still, Matthew D., Miloscio, Lawrence, Van Zyl, Tavé, Di Gioia, Silvio Alessandro, Brumpton, Ben, Krebs, Kristi, Åsvold, Bjørn Olav, Chen, Esteban, Chavali, Venkata R. M., Fury, Wen, Gudiseva, Harini V., Hyde, Sarah, Jorgenson, Eric, Lefebvre, Stephanie, Li, Dadong, Li, Alexander, Mclninch, James, Patel, Brijeshkumar, Rabinowitz, Jeremy S., Salowe, Rebecca, Schurmann, Claudia, Seidelin, Anne-Sofie, Stahl, Eli, Sun, Dylan, Teslovich, Tanya M., Tybjærg-Hansen, Anne, Willer, Cristen, Waldron, Scott, Walley, Sabrina, Yang, Hua, Zaveri, Sarthak, Hu, Ying, Hveem, Kristian, Melander, Olle, Milani, Lili, Stender, Stefan, O’Brien, Joan M., Jones, Marcus B., Abecasis, Gonçalo R., Cantor, Michael N., Weyne, Jonathan, Karalis, Katia, Economides, Aris, Della Gatta, Giusy, Ferreira, Manuel A., Yancopoulos, George D., Baras, Aris, Romano, Carmelo, Coppola, Giovanni

“…Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering intraocular pressure (IOP), a risk factor for glaucoma, but most…”
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Mechanisms of Glucocorticoid-Induced Ocular Hypertension and Glaucoma by Patel, Gaurang C

“…Glucocorticoid (GC)-induced ocular hypertension (OHT) is a serious side-effect of prolonged GC therapy that can lead to iatrogenic glaucoma and permanent…”
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Aspirin Does Not Increase Homologous Blood Requirements in Elective Coronary Bypass Surgery by Reich, David L., Patel, Gaurang C., Vela-Cantos, Francis, Bodian, Carol, Lansman, Steven

“…Studies have demonstrated increased homologous blood product requirements in patients on aspirin (ASA) undergoing cardiac surgery. We reexamined the influence…”
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Effects of ionic and nonionic contrast media on in vitro and in vivo platelet activation by Albanese, James R., Venditto, John A., Patel, Gaurang C., Ambrose, John A.

“…An increased incidence of thromboembolic events has been associated with nonionic contrast media. Although it has been demonstrated that nonionic contrast…”
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