Search Results - "Patel, Diyan"
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Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)
Published in Scientific reports (17-06-2020)“…Triple-knockout (TKO) pigs (with added protective human transgenes) are likely to be optimal sources of organs for clinical organ xenotransplantation because…”
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Journal Article -
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Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation
Published in Scientific reports (16-07-2020)“…Triple-knockout (TKO) pigs may be ideal sources of organs for clinical xenotransplantation because many humans have no preformed antibody to TKO pig cells…”
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Journal Article -
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PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration
Published in Frontiers in immunology (2023)“…Age-related macular degeneration (AMD) is a chronic, progressive retinal disease characterized by an inflammatory response mediated by activated macrophages…”
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PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration
Published in Pharmaceuticals (Basel, Switzerland) (01-04-2024)“…The alternative pathway of the complement system is implicated in the etiology of age-related macular degeneration (AMD). Complement depletion with…”
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Phosphate-Induced Calcification Impairs Aortic Stress in an ex vivo Mouse Model of Chronic Kidney Disease
Published 01-01-2022“…There are well over 100,000 Americans on the kidney transplant list with a median wait time of 3.6 years. However, about 17 American die each day waiting for a…”
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Dissertation -
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NEW WORLD MONKEYS AS MODELS FOR TESTING TRIPLE-KNOCKOUT (TKO) PIG RED BLOOD CELL OR SKIN TRANSPLANTS
Published in Transplantation (01-09-2020)Get full text
Journal Article