Search Results - "Patel, Chirag"

In silico prediction of potential inhibitors for the main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repurposing by Kumar, Yogesh, Singh, Harvijay, Patel, Chirag N.

“…The rapidly enlarging COVID-19 pandemic caused by the novel SARS-corona virus-2 is a global public health emergency of an unprecedented level. Unfortunately no…”
Get full text

An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus by Patel, Chirag J, Bhattacharya, Jayanta, Butte, Atul J

“…Type 2 Diabetes (T2D) and other chronic diseases are caused by a complex combination of many genetic and environmental factors. Few methods are available to…”
Get full text

Targeting metabolism to regulate immune responses in autoimmunity and cancer by Patel, Chirag H., Leone, Robert D., Horton, Maureen R., Powell, Jonathan D.

“…Metabolic programming is emerging as a critical mechanism to alter immune cell activation, differentiation and function. Targeting metabolism does not…”
Get full text

Identification of novel inhibitors of SARS‐CoV‐2 main protease (Mpro) from Withania sp. by molecular docking and molecular dynamics simulation by Verma, Surjeet, Patel, Chirag N., Chandra, Muktesh

“…Since December 2019, coronavirus disease (COVID‐19) has claimed the lives of millions of people across the globe. To date, no medicine is available for the…”
Get full text

A standard database for drug repositioning by Brown, Adam S., Patel, Chirag J.

“…Drug repositioning, the process of discovering, validating, and marketing previously approved drugs for new indications, is of growing interest to academia and…”
Get full text

Intestinal Absorption of Fructose by Ferraris, Ronaldo P, Choe, Jun-yong, Patel, Chirag R

“…Increased understanding of fructose metabolism, which begins with uptake via the intestine, is important because fructose now constitutes a physiologically…”
Get full text

Ethnic Differences in the Relationship Between Insulin Sensitivity and Insulin Response: A systematic review and meta-analysis by KODAMA, Keiichi, TOJJAR, Damon, YAMADA, Satoru, TODA, Kyoko, PATEL, Chirag J, BUTTE, Atul J

“…Human blood glucose levels have likely evolved toward their current point of stability over hundreds of thousands of years. The robust population stability of…”
Get full text

Morning exercise as fasted-state activity. Reply to Chacko E [letter] by Tian, Caiwei, Patel, Chirag J.

Get full text

The Landscape of Genetic Content in the Gut and Oral Human Microbiome by Tierney, Braden T., Yang, Zhen, Luber, Jacob M., Beaudin, Marc, Wibowo, Marsha C., Baek, Christina, Mehlenbacher, Eleanor, Patel, Chirag J., Kostic, Aleksandar D.

“…Despite substantial interest in the species diversity of the human microbiome and its role in disease, the scale of its genetic diversity, which is fundamental…”
Get full text

Software Application Profile: PXStools—an R package of tools for conducting exposure-wide analysis and deriving polyexposure risk scores by He, Yixuan, Patel, Chirag J

“…Abstract Motivation Investigating the aggregate burden of environmental factors on human traits and diseases requires consideration of the entire ‘exposome’…”
Get full text

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion by Leone, Robert D, Zhao, Liang, Englert, Judson M, Sun, Im-Meng, Oh, Min-Hee, Sun, Im-Hong, Arwood, Matthew L, Bettencourt, Ian A, Patel, Chirag H, Wen, Jiayu, Tam, Ada, Blosser, Richard L, Prchalova, Eva, Alt, Jesse, Rais, Rana, Slusher, Barbara S, Powell, Jonathan D

“…The metabolic characteristics of tumors present considerable hurdles to immune cell function and cancer immunotherapy. Using a glutamine antagonist, we…”
Get full text

Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease by Patel, Chirag H, Powell, Jonathan D

“…Highlights • Metabolic reprogramming is intimately linked to T cell activation. • Different T cell subsets have different metabolic demands. • Selectivity of…”
Get full text

Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations by Patel, Chirag J, Burford, Belinda, Ioannidis, John P.A

“…Abstract Objectives Model specification—what adjusting variables are analytically modeled—may influence results of observational associations. We present a…”
Get full text

Prevalence of Fatty Liver Disease is Driven by Prediabetes and Diabetes: US NHANES 2017–2018 by Claypool, Kajal, Patel, Chirag J.

Get full text

STI/HIV Testing and Prevalence of Gonorrhea and Chlamydia Among Persons with Their Specified-Type Sex Partner by Patel, Chirag G., Tao, Guoyu

“…Previous studies have shown that sexually transmitted infections (STI) and human immunodeficiency virus (HIV) testing has varied, but STI prevalence was not…”
Get full text

Fast-track development of vaccines for SARS-CoV-2: The shots that saved the world by Chavda, Vivek P, Yao, Qian, Vora, Lalitkumar K, Apostolopoulos, Vasso, Patel, Chirag A, Bezbaruah, Rajashri, Patel, Aayushi B, Chen, Zhe-Sheng

“…In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The…”
Get full text

Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium by Johnston, Bradley C, Zeraatkar, Dena, Han, Mi Ah, Vernooij, Robin W M, Valli, Claudia, El Dib, Regina, Marshall, Catherine, Stover, Patrick J, Fairweather-Taitt, Susan, Wójcik, Grzegorz, Bhatia, Faiz, de Souza, Russell, Brotons, Carlos, Meerpohl, Joerg J, Patel, Chirag J, Djulbegovic, Benjamin, Alonso-Coello, Pablo, Bala, Malgorzata M, Guyatt, Gordon H

“…This article has been corrected. The original version (PDF) is appended to this article as a Supplement. Dietary guideline recommendations require…”
Get full text

MEK Pathway Inhibitor-Mediated Response in BRAF V600-Mutant Melanoma with Brain Parenchymal and Leptomeningeal Metastases by Alhusaini, Saud, Naya, Lewis, Reddy, Sunil A, Patel, Chirag B

Get full text

Anti-cancer mechanisms of action of therapeutic alternating electric fields (tumor treating fields [TTFields]) by Shams, Shadi, Patel, Chirag B

“…Despite improved survival outcomes across many cancer types, the prognosis remains grim for certain solid organ cancers including glioblastoma and pancreatic…”
Get full text

Sexually Transmitted Infection/Human Immunodeficiency Virus (STI/HIV) Testing, STIs, and HIV Pre-exposure Prophylaxis Use Among Men Who Have Sex With Men and Men Who Have Sex With Men and Women in the United States, 2019–2022 by Tao, Guoyu, Patel, Chirag G, He, Larry, Workowski, Kimberly

“…Abstract Background Routine sexually transmitted infection and human immunodeficiency virus (STI/HIV) testing and HIV pre-exposure prophylaxis (PrEP) use are…”
Get full text