Search Results - "Patel, Bhavik A."

Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites by Lund, Mari L., Egerod, Kristoffer L., Engelstoft, Maja S., Dmytriyeva, Oksana, Theodorsson, Elvar, Patel, Bhavik A., Schwartz, Thue W.

“…5-HT storing enterochromaffin (EC) cells are believed to respond to nutrient and gut microbial components, and 5-HT receptor-expressing afferent vagal neurons…”
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Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer by Flaherty, Renée L, Owen, Matthew, Fagan-Murphy, Aidan, Intabli, Haya, Healy, David, Patel, Anika, Allen, Marcus C, Patel, Bhavik A, Flint, Melanie S

“…Psychological stress increases the circulating levels of the stress hormones cortisol and norepinephrine (NE). Chronic exposure to elevated stress hormones has…”
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Escherichia coli Nissle 1917 enhances bioavailability of serotonin in gut tissues through modulation of synthesis and clearance by Nzakizwanayo, Jonathan, Dedi, Cinzia, Standen, Guy, Macfarlane, Wendy M., Patel, Bhavik A., Jones, Brian V.

“…Accumulating evidence shows indigenous gut microbes can interact with the human host through modulation of serotonin (5-HT) signaling. Here we investigate the…”
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Stress hormone-mediated acceleration of breast cancer metastasis is halted by inhibition of nitric oxide synthase by Flaherty, Renée L., Intabli, Haya, Falcinelli, Marta, Bucca, Giselda, Hesketh, Andrew, Patel, Bhavik A., Allen, Marcus C., Smith, Colin P., Flint, Melanie S.

“…Stress hormones have been shown to be important mediators in driving malignant growth and reducing treatment efficacy in breast cancer. Glucocorticoids can…”
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Disruption of Escherichia coli Nissle 1917 K5 capsule biosynthesis, through loss of distinct kfi genes, modulates interaction with intestinal epithelial cells and impact on cell health by Nzakizwanayo, Jonathan, Kumar, Sandeep, Ogilvie, Lesley A, Patel, Bhavik A, Dedi, Cinzia, Macfarlane, Wendy M, Jones, Brian V

“…Escherichia coli Nissle 1917 (EcN) is among the best characterised probiotics, with a proven clinical impact in a range of conditions. Despite this, the…”
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Ex Vivo Electrochemical pH Mapping of the Gastrointestinal Tract in the Absence and Presence of Pharmacological Agents by Rajan, Teena S, Read, Tania L, Abdalla, Aya, Patel, Bhavik A, Macpherson, Julie V

“…Ex vivo pH profiling of the upper gastrointestinal (GI) tract (of a mouse), using an electrochemical pH probe, in both the absence and presence of…”
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Poly(lactic acid)/Carbon Nanotube Composite Microneedle Arrays for Dermal Biosensing by Skaria, Eldhose, Patel, Bhavik A, Flint, Melanie S, Ng, Keng Wooi

“…Minimally invasive, reliable and low-cost in vivo biosensors that enable real-time detection and monitoring of clinically relevant molecules and biomarkers can…”
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Bicomponent composite electrochemical sensors for sustained monitoring of hydrogen peroxide in breast cancer cells by Abdalla, Aya, Jones, Will, Flint, Melanie S., Patel, Bhavik A.

“…Hydrogen peroxide (H2O2) is a molecule that plays an important role in cancer. Low concentrations in H2O2 have an important physiological role in signalling…”
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3D-printed electrochemical pestle and mortar for identification of falsified pharmaceutical tablets by Shergill, Ricoveer S., Farlow, Anna, Perez, Fernando, Patel, Bhavik A.

“…Falsified medicines and healthcare supplements provide a major risk to public health and thus early identification is critical. Although a host of analytical…”
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Boron-Doped Diamond Microelectrodes Reveal Reduced Serotonin Uptake Rates in Lymphocytes from Adult Rhesus Monkeys Carrying the Short Allele of the 5-HTTLPR by Singh, Yogesh S, Sawarynski, Lauren E, Michael, Heather M, Ferrell, Robert E, Murphey-Corb, Michael A, Swain, Greg M, Patel, Bhavik A, Andrews, Anne M

“…Uptake resolved by high-speed chronoamperometry on a second-by-second basis has revealed important differences in brain serotonin transporter function…”
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Subsecond Voltammetric Separation between Dopamine and Serotonin in the Presence of Ascorbate by Anastassiou, Costas A, Patel, Bhavik A, Arundell, Martin, Yeoman, Mark S, Parker, Kim H, O'Hare, Danny

“…Although voltammetry has proved an important tool for unraveling the dynamics of specific neurotransmitter molecules during the past decade, it has been very…”
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Paracrine relationship between incretin hormones and endogenous 5‐hydroxytryptamine in the small and large intestine by Tough, Iain R., Lund, Mari L., Patel, Bhavik A., Schwartz, Thue W., Cox, Helen M.

“…Background Enterochromaffin (EC) cell‐derived 5‐hydroxytryptamine (5‐HT) is a mediator of toxin‐induced reflexes, initiating emesis via vagal and central 5‐HT3…”
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Incorporation of analytical chemistry in the undergraduate curriculum: examples from different regions of the world by Wenzel, Thomas J., Forbes, Patricia B. C., Galarreta, Betty C., Patel, Bhavik A., Vogel, Martin, Wong, Danny K. Y.

“…Graphical Abstract…”
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Enteric Glia Mediate Neuron Death in Colitis Through Purinergic Pathways That Require Connexin-43 and Nitric Oxide by Brown, Isola A.M, McClain, Jonathon L, Watson, Ralph E, Patel, Bhavik A, Gulbransen, Brian D

“…Background & Aims The concept of enteric glia as regulators of intestinal homeostasis is slowly gaining acceptance as a central concept in…”
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Inhibiting Inducible Nitric Oxide Synthase in Enteric Glia Restores Electrogenic Ion Transport in Mice With Colitis by MacEachern, Sarah J, Patel, Bhavik A, Keenan, Catherine M, Dicay, Michael, Chapman, Kevin, McCafferty, Donna-Marie, Savidge, Tor C, Beck, Paul L, MacNaughton, Wallace K, Sharkey, Keith A

“…Background & Aims Disturbances in the control of ion transport lead to epithelial barrier dysfunction in patients with colitis. Enteric glia regulate…”
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Effects of age and social isolation on murine hippocampal biochemistry and behavior by Panossian, Annabelle, Cave, Michael W., Patel, Bhavik A., Brooks, Emily L., Flint, Melanie S., Yeoman, Mark S.

“…•Social isolation (SI) alters behavior and brain biochemistry in young mice.•Old mice either failed to respond or showed a synergistic response with age to…”
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Fluoxetine and thioridazine inhibit efflux and attenuate crystalline biofilm formation by Proteus mirabilis by Nzakizwanayo, Jonathan, Scavone, Paola, Jamshidi, Shirin, Hawthorne, Joseph A., Pelling, Harriet, Dedi, Cinzia, Salvage, Jonathan P., Hind, Charlotte K., Guppy, Fergus M., Barnes, Lara M., Patel, Bhavik A., Rahman, Khondaker M., Sutton, Mark J., Jones, Brian V.

“…Proteus mirabilis forms extensive crystalline biofilms on indwelling urethral catheters that block urine flow and lead to serious clinical complications. The…”
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Nitric oxide regulation of colonic epithelial ion transport: a novel role for enteric glia in the myenteric plexus by MacEachern, Sarah J., Patel, Bhavik A., McKay, Derek M., Sharkey, Keith A.

“…Non‐technical summary  The enteric nervous system of the gastrointestinal tract regulates all the functions of the gut. Enteric neurons are surrounded and…”
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Region specific differences in the effect of propofol on the murine colon result in dysmotility by Diss, Lucy B., Villeneuve, Shannon, Pearce, Kim R., Yeoman, Mark S., Patel, Bhavik A.

“…Propofol is the most widely used intravenous anaesthetic agent for maintenance of anaesthesia and sedation. Studies in varying regions of the bowel have shown…”
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Understanding the Stability of Dopamine and Dobutamine Over 24 h in Simulated Neonatal Ward Conditions by Kirupakaran, Katherine, Mahoney, Liam, Rabe, Heike, Patel, Bhavik A.

“…Objectives Our objectives were to investigate the possible effects of temperature and light on the stability of dopamine and dobutamine continuous infusions…”
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