Search Results - "Patel, Ashwin P."

Use of Daratumumab in Patients With Previously Treated Multiple Myeloma by Patel, Ashwin P

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"Selection of statistical tests influences the interpretation of a study outcome" a comment on "Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease. Prostaglandins Leukot Essent Fatty Acids. 2023 Jun; 193:102574. Doi: 10.1016/j.plefa.2023.102574. Epub 2023 Apr 7. PMID: 37121179" by Patel, Ashwin P

“…Parametric tests such as t-tests require a normal distribution of data. However, the determination of normal distribution may not be conclusive while dealing…”
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Letter to the Editor concerning “Age- and sex-related changes in facet orientation and tropism in lower lumbar spine: an MRI study of 600 patients” by Degulmadi D, et al. (Eur Spine J [2019] 28:961–966, https://doi.org/10.1007/s00586-019-05953-y) by Patel, Ashwin P.

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Concerns With Statistical Analysis of 2016 CDC Opioid Guideline and Sickle Cell Outcomes by Patel, Ashwin P, McLemore, Morgan, Sheehan, Vivien A

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Dapsone for immune thrombocytopenic purpura in children and adults by Patel, Ashwin P., Patil, Amit S.

“…Abstract Dapsone is one of the second line treatments of immune thrombocytopenic purpura (ITP). Dapsone is cheap and has response rates comparable to other…”
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Validation of the breathmobile case identification survey for asthma screening in children with sickle cell disease by Patel, Ashwin P., Krupani, Soornela, Stark, James M., Mosquera, Ricardo A., Waller, Dorothy Kim, Gonzales, Traci, Brown, Deborah L., Nguyen, Trinh T., Jon, Cindy K., Yadav, Aravind

“…Background: Asthma is a chronic airway disorder with variable/recurring symptoms, airflow obstruction, bronchial hyperresponsiveness, and an inflammation. The…”
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A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease by Rampersaud, Evadnie, Kang, Guolian, Palmer, Lance E., Rashkin, Sara R., Wang, Shuoguo, Bi, Wenjian, Alberts, Nicole M., Anghelescu, Doralina, Barton, Martha, Birch, Kirby, Boulos, Nidal, Brandow, Amanda M., Brooke, Russell John, Chang, Ti-Cheng, Chen, Wenan, Cheng, Yong, Ding, Juan, Easton, John, Hodges, Jason R., Kanne, Celeste K., Levy, Shawn, Mulder, Heather, Patel, Ashwin P., Puri, Latika, Rosencrance, Celeste, Rusch, Michael, Sapkota, Yadav, Sioson, Edgar, Sharma, Akshay, Tang, Xing, Thrasher, Andrew, Wang, Winfred, Yao, Yu, Yasui, Yutaka, Yergeau, Donald, Hankins, Jane S., Sheehan, Vivien A., Downing, James R., Estepp, Jeremie H., Zhang, Jinghui, DeBaun, Michael, Wu, Gang, Weiss, Mitchell J.

“…Individuals with monogenic disorders can experience variable phenotypes that are influenced by genetic variation. To investigate this in sickle cell disease…”
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β-Thalassemia Mutations in Western India: Outcome of Prenatal Diagnosis in a Hemoglobinopathies Project by Patel, Ashwin P., Patel, Rupesh B., Patel, Saumyaa A., Vaniawala, Salil N., Patel, Dipika S., Shrivastava, Naina S., Sharma, Narmadeshwar P., Zala, Jayendrasinh V., Parmar, Prakash H., Naik, Madhuben R.

“…Abstract Prenatal diagnosis (PND) is one of the most cost effective preventive methods, but it is available only in the large cities of India. Therefore, we…”
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Long term survival in aggressive NK-cell leukemia by Patel, Ashwin P., Ghatak, Somsuvra B., Patel, Jagruti A.

“…Aggressive natural killer cell leukemia (ANKL) is a rare type of leukemia. It is rapidly progressing and the outcome is poor, with short survival. There is…”
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Idiopathic autoimmune thrombocytopenia and neutropenia in siblings by Patel, Ashwin P.

“…: Familial incidences of autoimmune disorders involving red cells, white cells and platelets are rare. Two cases of autoimmune neutropenia and thrombocytopenia…”
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Red Cell Rheology and Blood Viscosity in Pediatric Individuals Having Received Allogenic Hematopoietic Stem Cell Transplantation or Ex Vivo Autologous Gene Therapy for Sickle Cell Disease by Patel, Ashwin P., Kanne, Celeste K., Stenger, Elizabeth O, John, Tami D., Sheehan, Vivien A.

“…Background: Allogenic hematopoietic stem cell transplantation (HCT) and ex vivo autologous gene therapies (GT) are potentially curative treatments for sickle…”
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Impact of Vaso-Occlusive Crises on the Transcriptomes of Patients with Sickle Cell Disease by Bhat, Varsha, Potdar, Alka A, Patel, Ashwin P, Gibson, Gregory, Yu, G. Karen, Sheehan, Vivien A

“…Introduction: Sickle cell disease (SCD) is an inherited, multisystem blood disorder that affects millions of people worldwide and is particularly common among…”
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Increase in Fetal Hemoglobin Levels in Pediatric Patients with Sickle Cell Disease after Vitamin D Replacement by Patel, Ashwin P, Waller, Dorothy Kim, Sheehan, Vivien A.

“…Background: High fetal hemoglobin (HbF) levels reduce mortality and morbidity in sickle cell disease (SCD). Results from a prior clinical trial to assess…”
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An analysis of 8 cases of factor X deficiency by Shah, Nilam M., Patel, Ashwin P.

“…Background Factor X deficiency is a rare coagulation defect. There are occasional reports of factor X deficiency from India. Difficulty in accurate diagnosis…”
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An analysis of 30 cases of myelodysplastic syndrome by Shah, Nilam M, Prajapati, Sanjay G, Adesara, Rashmin P, Patel, Ashwin P

“…Myelodysplastic syndrome (MDS) is a clonal disorder of pluripotential stem cells of the bone marrow. The purpose of the study was to obtain epidemiological…”
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Rheological Characteristics of Elderly Individuals with Sickle Cell Disease Compared with an Adult Sickle Cell Population by Yoo, Justin J, Zgodny, Jordan, Hernandez, Britney, Darazim, Jawa, Patel, Ashwin P, El Rassi, Fuad, Yu, G. Karen, Potdar, Alka A, Sheehan, Vivien A.

“…Introduction: Individuals with sickle cell disease (SCD) have a shorter life expectancy (median age 43 years in the US) compared with the general population…”
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Evaluation of the Impact of a Naturally Occurring Beta Hemoglobin Variant, Hb G-Makassar, on Mature Red Blood Cell Function and Pathology in a Sickle Cell Disease Mouse Model by Kostamo, Zachary, Darazim, Jawa, Hernandez, Britney, Pendergast, Alex, Zgodny, Jordan, Evans, Erica N, Zhang, Yankai, Patel, Ashwin P, Kanne, Celeste K., Budak, Elizabeth, Jenkins, Rebecca, Haupt, Daniel, Winton, Valerie, Yan, Bo, Hartigan, Adam, Chu, Haihua, Ciaramella, Giuseppe, Sheehan, Vivien A.

“…Background: Gene based therapy may provide a cure for individuals with sickle cell disease (SCD); base editing is a novel strategy with the ability to directly…”
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Radchip: A Laminin-Lined Red Blood Cell (RBC) Adhesion Device for Functional Characterization and Clinical Evaluation of Sickle RBCs at Steady-State by Evans, Erica N, Williams, Evelyn K, Kanne, Celeste K., Fibben, Kirby A, Patel, Ashwin P., Abel, Lindsey, Fay, Meredith Ellen, Patwardhan, Akshay A, Darazim, Jawa, Kostamo, Zachary, Lam, Wilbur, Sheehan, Vivien A.

“…Sickle cell disease (SCD) is a genetic disorder caused by a point mutation in the beta-globin gene producing an abnormal hemoglobin (HbS) which, under…”
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Evaluation of GBT021601 As a Therapeutic Agent to Restore Bone Marrow Health and Effective Erythropoiesis in a Sickle Mouse Model by Hernandez, Britney, Priyadarshini, Anupama, Kostamo, Zachary, Zhang, Yankai, Patel, Ashwin P, Pendergast, Michael A, Jupelli, Madhulika, Huang, Heli, Nguyen Dang, Annie, Pochron, Mira Patel, Dufu, Kobina, Sheehan, Vivien A

“…Introduction: Hypoxia-mediated damage resulting from vaso-occlusion in sickle cell disease (SCD) leads to abnormal angiogenesis, such as occurs with moyamoya…”
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Comparison of Devices That Measure Sickle Red Cell Deformability by Patwardhan, Akshay A, Oshabaheebwa, Solomon, Delianides, Christopher A., Sekyonda, Zoe, Patel, Ashwin P, Evans, Erica N, Yoo, Justin J, Abel, Lindsey, Suster, Michael A., Mohseni, Pedram, Gurkan, Umut A., Sheehan, Vivien A

“…Background With the emergence of novel pharmacologic and gene-based therapies, identifying the rheological and biophysical RBC abnormalities of sickle cell…”
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