Search Results - "Patel, Amun C."
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Emerging Methods and Applications to Decrypt Allostery in Proteins and Nucleic Acids
Published in Journal of molecular biology (15-09-2022)“…[Display omitted] •Molecular simulations meet graph theory to decrypt allostery.•Enhanced network models describe allostery over long timescales.•Ab-initio…”
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Unveiling Cas8 dynamics and regulation of a transposon-encoded cascade-TniQ complex
Published in Biophysical journal (10-02-2023)Get full text
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Dimerization of the deaminase domain and locking interactions with Cas9 boost base editing efficiency in ABE8e
Published in Nucleic acids research (21-11-2024)“…CRISPR-based DNA adenine base editors (ABEs) hold remarkable promises to address human genetic diseases caused by point mutations. ABEs were developed by…”
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Defining the allosteric role of RNA in the CRISPR-associated Cas13a protein activation
Published in Biophysical journal (10-02-2023)Get full text
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Domain dynamics and plasticity of the transposon-encoded cascade-TniQ system
Published in Biophysical journal (11-02-2022)Get full text
Journal Article