Search Results - "Patel, Amanda J"

Properties and modulation of mammalian 2P domain K+ channels by Patel, Amanda J., Honoré, Eric

“…Mammalian 2P domain K + channels are responsible for background or ‘leak’ K + currents. These channels are regulated by various physical and chemical stimuli,…”
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The 2P-domain K+ channels: role in apoptosis and tumorigenesis by Patel, Amanda J, Lazdunski, Michel

“…Two-pore (2P)-domain K+ channels have been shown recently to play a critical role in both cell apoptosis and tumorigenesis. The activity of two-pore,…”
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Inhalational anesthetics activate two-pore-domain background K + channels by Lazdunski, Michel, Patel, Amanda J, Honoré, Eric, Lesage, Florian, Fink, Michel, Romey, Georges

“…Volatile anesthetics produce safe, reversible unconsciousness, amnesia and analgesia via hyperpolarization of mammalian neurons. In molluscan pacemaker…”
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A comprehensive library of fluorescent constructs of SARS‐CoV‐2 proteins and their initial characterisation in different cell types by Miserey‐Lenkei, Stéphanie, Trajkovic, Katarina, D'Ambrosio, Juan Martín, Patel, Amanda J, Čopič, Alenka, Mathur, Pallavi, Schauer, Kristine, Goud, Bruno, Albanèse, Véronique, Gautier, Romain, Subra, Melody, Kovacs, David, Barelli, Hélène, Antonny, Bruno

“…Background Information Comprehensive libraries of plasmids for SARS‐CoV‐2 proteins with various tags (e.g., Strep, HA, Turbo) are now available. They enable…”
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Disruption of Mitochondrial Respiration Inhibits Volume-Regulated Anion Channels and Provokes Neuronal Cell Swelling by Patel, Amanda J, Lauritzen, Inger, Lazdunski, Michel, Honore, Eric

“…Hypoxia and inhibitors of mitochondrial respiration impair the regulatory volume decrease (RVD) of cerebellar granule neurons after hypotonic swelling. RVD is…”
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Lipid and mechano-gated 2P domain K + channels by Patel, Amanda J, Lazdunski, Michel, Honoré, Eric

“…The two pore domain K + channels TREK and TRAAK are opened by membrane stretch. The activating mechanical force comes from the bilayer membrane and is…”
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TREK-1 is a heat-activated background K+ channel by Maingret, François, Lauritzen, Inger, Patel, Amanda J., Heurteaux, Catherine, Reyes, Roberto, Lesage, Florian, Lazdunski, Michel, Honoré, Eric

“…Peripheral and central thermoreceptors are involved in sensing ambient and body temperature, respectively. Specialized cold and warm receptors are present in…”
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K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels by Lauritzen, Inger, Zanzouri, Marc, Honoré, Eric, Duprat, Fabrice, Ehrengruber, Markus U, Lazdunski, Michel, Patel, Amanda J

“…Rat mature cerebellar granule, unlike hippocampal neurons, die by apoptosis when cultured in a medium containing a physiological concentration of K+ but…”
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A mammalian two pore domain mechano-gated S-like K+ channel by Patel, Amanda J., Honoré, Eric, Maingret, François, Lesage, Florian, Fink, Michel, Duprat, Fabrice, Lazdunski, Michel

“…Aplysia S‐type K+ channels of sensory neurons play a dominant role in presynaptic facilitation and behavioural sensitization. They are closed by serotonin via…”
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The endocannabinoid anandamide is a direct and selective blocker of the background K+ channel TASK-1 by Maingret, François, Patel, Amanda J., Lazdunski, Michel, Honoré, Eric

“…TASK‐1 encodes an acid‐ and anaesthetic‐sensitive background K+ current, which sets the resting membrane potential of both cerebellar granule neurons and…”
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Lysophospholipids Open the Two-pore Domain Mechano-gated K+ Channels TREK-1 and TRAAK by Maingret, François, Patel, Amanda J., Lesage, Florian, Lazdunski, Michel, Honoré, Eric

“…The two-pore (2P) domain K+channels TREK-1 and TRAAK are opened by membrane stretch as well as arachidonic acid (AA) (Patel, A. J., Honoré, E., Maingret, F.,…”
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Mechano- or Acid Stimulation, Two Interactive Modes of Activation of the TREK-1 Potassium Channel by Maingret, François, Patel, Amanda J., Lesage, Florian, Lazdunski, Michel, Honoré, Eric

“…TREK-1 is a member of the novel structural class of K+ channels with four transmembrane segments and two pore domains in tandem (1, 2). TREK-1 is opened by…”
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The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK by Duprat, F, Lesage, F, Patel, A J, Fink, M, Romey, G, Lazdunski, M

“…Riluzole (RP 54274) is a potent neuroprotective agent with anticonvulsant, sedative, and anti-ischemic properties. It is currently used in the treatment of…”
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Anesthetic-sensitive 2P domain K+ channels by PATEL, Amanda J, HONORE, Eric

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TWIK-2, an Inactivating 2P Domain K+ Channel by Patel, A J, Maingret, F, Magnone, V, Fosset, M, Lazdunski, M, Honoré, E

“…We cloned human and rat TWIK-2 and expressed this novel 2P domain K + channel in transiently transfected COS cells. TWIK-2 is highly expressed in the…”
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myc Function and Regulation by Marcu, Kenneth B, Bossone, Steven A, Patel, Amanda J

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MAZ, a Zinc Finger Protein, Binds to c-MYC and C2 Gene Sequences Regulating Transcriptional Initiation and Termination by Bossone, Steven A., Asselin, Claude, Patel, Amanda J., Marcu, Kenneth B.

“…ME1a1, a 16-base-pair nuclear factor binding site residing between the c-MYC P1and P2transcription initiation sites, is required for P2activity. A cDNA…”
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K+-dependent Cerebellar Granule Neuron Apoptosis by Lauritzen, Inger, Zanzouri, Marc, Honoré, Eric, Duprat, Fabrice, Ehrengruber, Markus U., Lazdunski, Michel, Patel, Amanda J.

“…Rat mature cerebellar granule, unlike hippocampal neurons, die by apoptosis when cultured in a medium containing a physiological concentration of K+ but…”
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A comprehensive library of fluorescent constructs of SARS‐CoV‐2 proteins and their initial characterisation in different cell types by Miserey‐lenkei, Stéphanie, Trajkovic, Katarina, d'Ambrosio, Juan Martín, Patel, Amanda J, Čopič, Alenka, Mathur, Pallavi, Schauer, Kristine, Goud, Bruno, Albanèse, Véronique, Gautier, Romain, Subra, Melody, Kovacs, David, Barelli, Hélène, Antonny, Bruno

“…Background Information. Comprehensive libraries of plasmids for SARS-CoV-2 proteins with various tags (e.g., Strep, HA, Turbo) are now available. They enable…”
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Kv2.1/Kv9.3, a novel ATP‐dependent delayed‐rectifier K+ channel in oxygen‐sensitive pulmonary artery myocytes by Patel, Amanda J., Lazdunski, Michel, Honoré, Eric

“…The molecular structure of oxygen‐sensitive delayed‐rectifier K+ channels which are involved in hypoxic pulmonary artery (PA) vasoconstriction has yet to be…”
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