Search Results - "Patel, AJ"

Anesthetic-sensitive 2P domain K+ channels by PATEL, Amanda J, HONORE, Eric

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DEVELOPMENT OF DEFATTED SOY FLOUR AND CASEINBASED BIO ADHESIVES FOR WOOD JOINT by Patel, DS, Dholakia, AB, Patel, VC, Patel, AJ

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A phospholipid sensor controls mechanogating of the K+ channel TREK-1 by Chemin, Jean, Patel, Amanda Jane, Duprat, Fabrice, Lauritzen, Inger, Lazdunski, Michel, Honoré, Eric

“…TREK‐1 (KCNK2 or K2P2.1) is a mechanosensitive K2P channel that is opened by membrane stretch as well as cell swelling. Here, we demonstrate that membrane…”
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DEVELOPMENT OF DEFATTED SOY FLOUR AND CASEIN-BASED BIO ADHESIVES FOR WOOD JOINT by Patel, DS, Dholakia, AB, Patel, VC, Patel, AJ

“…Wood adhesives were made using defatted soy flour, casein, sodium hydroxide (NaOH) and ethylene diamine. These eco-friendly wood adhesives are used to…”
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Validity of Wait Time Complaints and Effect of Trainee Presence in an Ophthalmic Emergency Department by Patel, Annika J, Markatia, Zahra, Sridhar, Jayanth, Cavuoto, Kara M

“…Press Ganey (PG) surveys can provide a more comprehensive evaluation of specific patient complaints through input of comments. In this paper, we evaluate the…”
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Properties and modulation of mammalian 2P domain K+ channels by Patel, Amanda J., Honoré, Eric

“…Mammalian 2P domain K + channels are responsible for background or ‘leak’ K + currents. These channels are regulated by various physical and chemical stimuli,…”
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Desensitization of mechano-gated K 2P channels by Honoré, Eric, Patel, Amanda Jane, Chemin, Jean, Suchyna, Thomas, Sachs, Frederick

“…The neuronal mechano-gated K 2P channels TREK-1 and TRAAK show pronounced desensitization within 100 ms of membrane stretch. Desensitization persists in the…”
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The 2P-domain K+ channels: role in apoptosis and tumorigenesis by Patel, Amanda J, Lazdunski, Michel

“…Two-pore (2P)-domain K+ channels have been shown recently to play a critical role in both cell apoptosis and tumorigenesis. The activity of two-pore,…”
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The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless Proteins by Tsuda, Hiroshi, Jafar-Nejad, Hamed, Patel, Akash J., Sun, Yaling, Chen, Hung-Kai, Rose, Matthew F., Venken, Koen J.T., Botas, Juan, Orr, Harry T., Bellen, Hugo J., Zoghbi, Huda Y.

“…Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease caused by an expanded glutamine tract in human Ataxin-1 (hAtx-1). The expansion stabilizes…”
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Lipid and mechano-gated 2P domain K + channels by Patel, Amanda J, Lazdunski, Michel, Honoré, Eric

“…The two pore domain K + channels TREK and TRAAK are opened by membrane stretch. The activating mechanical force comes from the bilayer membrane and is…”
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TREK-1 is a heat-activated background K+ channel by Maingret, François, Lauritzen, Inger, Patel, Amanda J., Heurteaux, Catherine, Reyes, Roberto, Lesage, Florian, Lazdunski, Michel, Honoré, Eric

“…Peripheral and central thermoreceptors are involved in sensing ambient and body temperature, respectively. Specialized cold and warm receptors are present in…”
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Cross-talk between the mechano-gated K 2P channel TREK-1 and the actin cytoskeleton by Jane Patel, Amanda, Lauritzen, Inger, Chemin, Jean, Honoré, Eric, Jodar, Martine, Guy, Nicolas, Lazdunski, Michel

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An intracellular proton sensor commands lipid- and mechano-gating of the K+ channel TREK-1 by Honoré, Eric, Maingret, François, Lazdunski, Michel, Patel, Amanda Jane

“…The 2P domain K+ channel TREK‐1 is widely expres sed in the nervous system. It is opened by a variety of physical and chemical stimuli including membrane…”
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Inhalational anesthetics activate two-pore-domain background K + channels by Lazdunski, Michel, Patel, Amanda J, Honoré, Eric, Lesage, Florian, Fink, Michel, Romey, Georges

“…Volatile anesthetics produce safe, reversible unconsciousness, amnesia and analgesia via hyperpolarization of mammalian neurons. In molluscan pacemaker…”
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K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels by Lauritzen, Inger, Zanzouri, Marc, Honoré, Eric, Duprat, Fabrice, Ehrengruber, Markus U, Lazdunski, Michel, Patel, Amanda J

“…Rat mature cerebellar granule, unlike hippocampal neurons, die by apoptosis when cultured in a medium containing a physiological concentration of K+ but…”
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A mammalian two pore domain mechano-gated S-like K+ channel by Patel, Amanda J., Honoré, Eric, Maingret, François, Lesage, Florian, Fink, Michel, Duprat, Fabrice, Lazdunski, Michel

“…Aplysia S‐type K+ channels of sensory neurons play a dominant role in presynaptic facilitation and behavioural sensitization. They are closed by serotonin via…”
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The endocannabinoid anandamide is a direct and selective blocker of the background K+ channel TASK-1 by Maingret, François, Patel, Amanda J., Lazdunski, Michel, Honoré, Eric

“…TASK‐1 encodes an acid‐ and anaesthetic‐sensitive background K+ current, which sets the resting membrane potential of both cerebellar granule neurons and…”
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Lysophospholipids Open the Two-pore Domain Mechano-gated K+ Channels TREK-1 and TRAAK by Maingret, François, Patel, Amanda J., Lesage, Florian, Lazdunski, Michel, Honoré, Eric

“…The two-pore (2P) domain K+channels TREK-1 and TRAAK are opened by membrane stretch as well as arachidonic acid (AA) (Patel, A. J., Honoré, E., Maingret, F.,…”
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Kv2.1/Kv9.3, a novel ATP‐dependent delayed‐rectifier K+ channel in oxygen‐sensitive pulmonary artery myocytes by Patel, Amanda J., Lazdunski, Michel, Honoré, Eric

“…The molecular structure of oxygen‐sensitive delayed‐rectifier K+ channels which are involved in hypoxic pulmonary artery (PA) vasoconstriction has yet to be…”
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Mechano- or Acid Stimulation, Two Interactive Modes of Activation of the TREK-1 Potassium Channel by Maingret, François, Patel, Amanda J., Lesage, Florian, Lazdunski, Michel, Honoré, Eric

“…TREK-1 is a member of the novel structural class of K+ channels with four transmembrane segments and two pore domains in tandem (1, 2). TREK-1 is opened by…”
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