Search Results - "Patchett, Amanda"

Improved 18S rDNA profiling of parasite communities in salmonid tissues using a host blocking primer by Patchett, Amanda L., Rigby, Megan L., Wynne, James W.

“…Sensitive screening of eukaryotic communities in aquaculture for research and management is limited by the availability of technologies that can detect…”
Get full text

A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I by Kayigwe, Ahab N., M. Darby, Jocelyn, Lyons, A. Bruce, L. Patchett, Amanda, Lisowski, Leszek, Liu, Guei-Sheung, S. Flies, Andrew

“…The devil facial tumour disease (DFTD) has led to a massive decline in the wild Tasmanian devil ( Sarcophilus harrisii ) population. The disease is caused by…”
Get full text

Tasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells by Petrohilos, Cleopatra, Patchett, Amanda, Hogg, Carolyn J., Belov, Katherine, Peel, Emma

“…The Tasmanian devil ( Sarcophilus harrisii ) is endangered due to the spread of Devil Facial Tumour Disease (DFTD), a contagious cancer with no current…”
Get full text

Mesenchymal plasticity of devil facial tumour cells during in vivo vaccine and immunotherapy trials by Patchett, Amanda L, Tovar, Cesar, Blackburn, Nicholas B, Woods, Gregory M, Lyons, A Bruce

“…Immune evasion is critical to the growth and survival of cancer cells. This is especially pertinent to transmissible cancers, which evade immune detection…”
Get full text

The Immunomodulatory Small Molecule Imiquimod Induces Apoptosis in Devil Facial Tumour Cell Lines by Patchett, Amanda L, Darby, Jocelyn M, Tovar, Cesar, Lyons, A Bruce, Woods, Gregory M

“…The survival of the Tasmanian devil (Sarcophilus harrisii) is threatened by devil facial tumour disease (DFTD). This transmissible cancer is usually fatal, and…”
Get full text

Heat shock proteins expressed in the marsupial Tasmanian devil are potential antigenic candidates in a vaccine against devil facial tumour disease by Tovar, Cesar, Patchett, Amanda L, Kim, Vitna, Wilson, Richard, Darby, Jocelyn, Lyons, A Bruce, Woods, Gregory M

“…The Tasmanian devil (Sarcophilus harrisii), the largest extant carnivorous marsupial and endemic to Tasmania, is at the verge of extinction due to the…”
Get full text

Curse of the devil: molecular insights into the emergence of transmissible cancers in the Tasmanian devil (Sarcophilus harrisii) by Patchett, Amanda L., Flies, Andrew S., Lyons, A. Bruce, Woods, Gregory M.

“…The Tasmanian devil ( Sarcophilus harrisii ) is the only mammalian species known to be affected by multiple transmissible cancers. Devil facial tumours 1 and 2…”
Get full text

Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii) by Patchett, Amanda L., Coorens, Tim H. H., Darby, Jocelyn, Wilson, Richard, McKay, Matthew J., Kamath, Karthik S., Rubin, Alan, Wakefield, Matthew, Mcintosh, Lachlan, Mangiola, Stefano, Pye, Ruth J., Flies, Andrew S., Corcoran, Lynn M., Lyons, A. Bruce, Woods, Gregory M., Murchison, Elizabeth P., Papenfuss, Anthony T., Tovar, Cesar

“…Devil facial tumour disease (DFTD) comprises two genetically distinct transmissible cancers (DFT1 and DFT2) endangering the survival of the Tasmanian devil (…”
Get full text

NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers by Ong, Chrissie E. B., Patchett, Amanda L., Darby, Jocelyn M., Chen, Jinying, Liu, Guei-Sheung, Lyons, A. Bruce, Woods, Gregory M., Flies, Andrew S.

“…Purpose Downregulation of MHC class I (MHC-I) is a common immune evasion strategy of many cancers. Similarly, two allogeneic clonal transmissible cancers have…”
Get full text

An oral bait vaccination approach for the Tasmanian devil facial tumor diseases by Flies, Andrew S, Flies, Emily J, Fox, Samantha, Gilbert, Amy, Johnson, Shylo R, Liu, Guei-Sheung, Lyons, A Bruce, Patchett, Amanda L, Pemberton, David, Pye, Ruth J

“…: The Tasmanian devil ( ) is the largest extant carnivorous marsupial. Since 1996, its population has declined by 77% primarily due to a clonal transmissible…”
Get more information

The toll-like receptor ligands Hiltonol ® (polyICLC) and imiquimod effectively activate antigen-specific immune responses in Tasmanian devils (Sarcophilus harrisii) by Patchett, Amanda L, Tovar, Cesar, Corcoran, Lynn M, Lyons, A Bruce, Woods, Gregory M

“…Devil facial tumour disease (DFTD) describes two genetically distinct transmissible tumours that pose a significant threat to the survival of the Tasmanian…”
Get full text

Generation and Testing of Fluorescent Adaptable Simple Theranostic (FAST) Proteins by Flies, Andrew S, Darby, Jocelyn M, Murphy, Peter R, Pinfold, Terry L, Patchett, Amanda L, Lennard, Patrick R

“…This protocol provides a step-by-step method to create recombinant fluorescent fusion proteins that can be secreted from mammalian cell lines. This builds on…”
Get full text

Challenges of an Emerging Disease: The Evolving Approach to Diagnosing Devil Facial Tumour Disease by Espejo, Camila, Patchett, Amanda L, Wilson, Richard, Lyons, A Bruce, Woods, Gregory M

“…Devil Facial Tumour Disease (DFTD) is an emerging infectious disease that provides an excellent example of how diagnostic techniques improve as…”
Get full text

Toll-like receptor signaling is functional in immune cells of the endangered Tasmanian devil by Patchett, Amanda L., Latham, Roger, Brettingham-Moore, Kate H., Tovar, Cesar, Lyons, A. Bruce, Woods, Gregory M.

“…Devil facial tumour disease (DFTD) is a fatally transmissible cancer that threatens the Tasmanian devil population. As Tasmanian devils do not produce an…”
Get full text

Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release by Pye, Ruth, Patchett, Amanda, McLennan, Elspeth, Thomson, Russell, Carver, Scott, Fox, Samantha, Pemberton, David, Kreiss, Alexandre, Baz Morelli, Adriana, Silva, Anabel, Pearse, Martin J, Corcoran, Lynn M, Belov, Katherine, Hogg, Carolyn J, Woods, Gregory M, Lyons, A Bruce

“…Devil facial tumor disease (DFTD) is renowned for its successful evasion of the host immune system. Down regulation of the major histocompatabilty complex…”
Get full text

Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells by Patchett, Amanda L, Wilson, Richard, Charlesworth, Jac C, Corcoran, Lynn M, Papenfuss, Anthony T, Lyons, Bruce A, Woods, Gregory M, Tovar, Cesar

“…As a topical cancer immunotherapy, the toll-like receptor 7 ligand imiquimod activates tumor regression via stimulation of immune cell infiltration and…”
Get full text

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers by Flies, Andrew S, Darby, Jocelyn M, Lennard, Patrick R, Murphy, Peter R, Ong, Chrissie E B, Pinfold, Terry L, De Luca, Alana, Lyons, A Bruce, Woods, Gregory M, Patchett, Amanda L

“…Around 40% of humans and Tasmanian devils ( ) develop cancer in their lifetime, compared to less than 10% for most species. In addition, devils are affected by…”
Get full text

Targeting transmissible cancers in animals by Patchett, Amanda, Woods, Gregory

“…New understanding of Tasmanian devil facial tumors informs therapy and prevention For thousands of years, a non–life-threatening tumor has been transmitted…”
Get full text

Genetic and genomic analyses of resistance to yersiniosis in Atlantic salmon (Salmo salar) assessed by tank challenge by Taylor, Richard S., Carvalheiro, Roberto, Patchett, Amanda L., Verbyla, Klara L., Carson, Jeremy, Wynne, James W., Evans, Brad S., Lind, Curtis E., King, Harry

“…The bacterial disease yersiniosis caused by the bacterium Yersinia ruckeri (non-Hagerman strain) has previously caused significant loss to the Atlantic salmon…”
Get full text