Search Results - "Patchen, Leslie C"

Resistance to chloroquine by Plasmodium vivax in Irian Jaya, Indonesia by Baird, J K, Basri, H, Purnomo, Bangs, M J, Subianto, B, Patchen, L C, Hoffman, S L

“…Evidence of emerging resistance to chloroquine by Plasmodium vivax is described from Irian Jaya (Indonesian New Guinea). Sixteen of 24 residents in the village…”
Get more information

Chloroquine-Resistant Plasmodium vivax from Indonesia by Schwartz, Ira K, Lackritz, Eve M, Patchen, Leslie C

“…To the Editor: Despite the global spread of chloroquine-resistant Plasmodium falciparum over the past 30 years, 1 chloroquine has remained effective for…”
Get full text

Effectiveness and Tolerance of Long-term Malaria Prophylaxis With Mefloquine: Need for a Better Dosing Regimen by Lobel, Hans O, Bernard, Kenneth W, Williams, Sharyon L, Hightower, Allen W, Patchen, Leslie C, Campbell, Carlos C

“…To measure the effectiveness and tolerance of long-term malaria prophylaxis with mefloquine, the incidence of Plasmodium falciparum malaria and of adverse…”
Get full text

Antibody response to preexposure human diploid-cell rabies vaccine given concurrently with chloroquine by Pappaioanou, M, Fishbein, D B, Dreesen, D W, Schwartz, I K, Campbell, G H, Sumner, J W, Patchen, L C, Brown, W J

“…We conducted a randomized controlled trial to evaluate the antibody response of freshman veterinary students to intradermal human diploid-cell rabies vaccine…”
Get more information

Chloroquine-resistant falciparum malaria in northern Malawi by Wolfe, M S, Breman, J G, Ainsworth, B, Teklehaimanot, A, Patchen, L C

“…An American Peace Corps volunteer contracted chloroquine-resistant Plasmodium falciparum malaria while serving in Malawi and taking regular chloroquine…”
Get more information

Neurologic reactions after a therapeutic dose of mefloquine by Patchen, L C, Campbell, C C, Williams, S B

Get more information

Amodiaquine as a prodrug: importance of metabolite(s) in the antimalarial effect of amodiaquine in humans by Churchill, F C, Patchen, L C, Campbell, C C, Schwartz, I K, Nguyen-Dinh, P, Dickinson, C M

“…Existing analytical methods for assaying the 4-aminoquinoline antimalarial amodiaquine in body fluids are nonspecific and obscure the fact that little or no…”
Get more information

Analysis of filter-paper-absorbed, finger-stick blood samples for chloroquine and its major metabolite using high-performance liquid chromatography with fluorescence detection by Patchen, L C, Mount, D L, Schwartz, I K, Churchill, F C

“…Methodology has been developed to facilitate the collection, transport, and analysis of blood samples in studies of chloroquine absorption and metabolism. The…”
Get more information

Isolation, characterization and standardization of a major metabolite of amodiaquine by chromatographic and spectroscopic methods by Churchill, F C, Mount, D L, Patchen, L C, Björkman, A

“…The amodiaquine metabolite 2-hydroxydesethylamodiaquine (designated metabolite II), one of the two major human metabolites of this antimalarial prodrug, is…”
Get more information

Failures of Combined Chloroquine and Fansidar® Prophylaxis in American Travelers to East Africa by Miller, Kirk D., Lobel, Hans 0., Pappaioanou, Marguerite, Patchen, Leslie C., Churchill, Frederick C.

Get full text

Hemoglobin Ohio (β142 Ala → Asp): A New Abnormal Hemoglobin With High Oxygen Affinity and Erythrocytosis by Moo-Penn, Winston F., Schneider, Rose G., Shih, Tzu-bi, Jones, Richard T., Govindarajan, Sugantha, Govindarajan, P.G., Patchen, Leslie C.

“…Hemoglobin Ohio [β142 (H20) Ala→Asp] was found in three members of a white family, all of whom showed erythrocytosis. The variant hemoglobin has a high oxygen…”
Get full text

Hemoglobin variants and methods used for their characterization during 7 years of screening at the Center for Disease Control by Moo-Penn, W F, Jue, D L, Johnson, M H, Bechtel, K C, Patchen, L C

“…During 7 years of screening for hemoglobin variants, over 75 rare variants have been characterized. Of these, 18 were described for the first time. This report…”
Get more information

Determination of mefloquine in blood by supercritical fluid chromatography with electron-capture detection by Mount, D L, Patchen, L C, Churchill, F C

“…Supercritical fluid chromatography (SFC) with electron-capture detection is described for the sensitive quantification of mefloquine in 0.1-ml blood samples…”
Get more information

Field-adapted method for high-performance thin-layer chromatographic detection and estimation of chloroquine in finger-stick blood by Mount, D L, Patchen, L C, Churchill, F C

Get more information

Field-adapted method for high-performance thin-layer chromatographic detection and estimation of chloroquine and desethylchloroquine in urine by Mount, D L, Nahlen, B L, Patchen, L C, Churchill, F C

“…A high-performance thin-layer chromatographic (HPTLC) method which can be used in remote field locations lacking electricity has been developed for selective…”
Get more information