Search Results - "Patchell, V B"

Binding sites involved in the interaction of actin with the N-terminal region of dystrophin by Levine, B.A., Moir, A.J.G., Patchell, V.B., Perry, S.V.

“…Two actin-binding sites have been identified on human dystrophin by proton NMR spectroscopy of synthetic peptides corresponding to defined regions of the…”
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The interaction of actin with dystrophin by Levine, B.A., Moir, A.J.G., Patchell, V.B., Perry, S.V.

“…Proton NMR spectroscopy of synthetic peptides corresponding to defined regions of human dystrophin has been employed to study the interaction with F-actin. No…”
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Conformational Effects of Serine Phosphorylation in Phospholamban Peptides by Quirk, Philip G., Patchell, Valerie B., Colyer, John, Drago, Guido A., Gao, Yuan

“…We have employed one‐ and two‐dimensional 1H‐NMR spectroscopy to study the effects of serine phosphorylation on peptide conformations, using cardiac…”
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Two-site phosphorylation of the phosphorylatable light chain (20-kDa light chain) of chicken gizzard myosin by Cole, H.A., Griffiths, H.S., Patchell, V.B., Perry, S.V.

“…When prepared under specified conditions chicken gizzard myosin was obtained which when incubated with ATP gave rise to a diphosphorylated as well as the…”
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Study of the phosphorylatable light chains of skeletal and gizzard myosins by nuclear magnetic resonance spectroscopy by Levine, B.A, Griffiths, H.S, Patchell, V.B, Perry, S.V

“…31P and 1H n.m.r. studies of the phosphorylatable light chains from rabbit fast skeletal and chicken gizzard muscles in the isolated state and in the intact…”
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Cytoplasmic interactions between phospholamban residues 1-20 and the calcium-activated ATPase of the sarcoplasmic reticulum by Sharma, P, Patchell, V B, Gao, Y, Evans, J S, Levine, B A

“…Phospholamban regulates the activity of the calcium-activated ATPase (CaATPase) of cardiac sarcoplasmic reticulum. Equilibrium fluorescence studies have shown…”
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The Interface between Caldesmon Domain 4b and Subdomain 1 of Actin Studied by Nuclear Magnetic Resonance Spectroscopy by Gao, Yuan, Patchell, Valerie B, Huber, Pia A. J, Copeland, Oneal, El-Mezgueldi, Mohammed, Fattoum, A, Calas, Bernard, Thorsted, Peter B, Marston, Steven B, Levine, Barry A

“…The ability of caldesmon to inhibit actomyosin ATPase activity involves the interaction of three nonsequential segments of caldesmon domain 4 (amino acids…”
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Sequential phosphorylation of adjacent serine residues on the N-terminal region of cardiac troponin-I: structure-activity implications of ordered phosphorylation by Quirk, Philip G., Patchell, Valerie B., Gao, Yuan, Levine, Barry A., Victor Perry, S.

“…We have used NMR spectroscopy to monitor the phosphorylation of a peptide corresponding to the N-terminal region of human cardiac troponin-I (residues 17–30),…”
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The Binding of Distinct Segments of Actin to Multiple Sites in the C-Terminus of Caldesmon: Comparative Aspects of Actin Interaction with Troponin-I and Caldesmon by Levine, Barry A, Mornet, Dominique, Bonet-Kerrache, Armelle, Strasburg, Gale M, Patchell, Valerie B, Perry, S. Victor, Huber, Pia A. J, Marston, Steven B, Slatter, David A, Evans, James S

“…Thin-filament-based regulation of the contractile response is considered to involve the interaction of actin with troponin-I in striated muscle and the…”
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Sites on the cytoplasmic region of phospholamban involved in interaction with the calcium‐activated ATPase of the sarcoplasmic reticulum by Levine, Barry A., Patchell, Valerie B., Sharma, Parveen, Gao, Yuan, Bigelow, Diana J., Yao, Qing, Goh, Swee, Colyer, John, Drago, Guido A., Perry, Samuel V.

“…Proton NMR studies have shown that when a peptide corresponding to the N‐terminal region of phospholamban, PLB(1–20), interacts with the Ca2+ATPase of the…”
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The Ordered Phosphorylation of Cardiac Troponin I by the cAMP‐Dependent Protein Kinase Structural Consequences and Functional Implications by Keane, Noeleen E., Quirk, Philip G., Gao, Yuan, Patchell, Valerie B., Perry, S. Victor, Levine, Barry A.

“…The pattern of phosphorylation of adjacent serine residues in several peptides based on the N‐terminal region of human cardiac troponin I has been analysed by…”
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Role of myosin light chain kinase in muscle contraction by Perry, S V, Cole, H A, Hudlicka, O, Patchell, V B, Westwood, S A

“…In resting striated muscles of the rabbit muscle in vivo, the phosphorylatable light chain is partially phosphorylated. Tetanic stimulation increased the level…”
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Structural study of gizzard caldesmon and its interaction with actin. Binding involves residues of actin also recognised by myosin subfragment 1 by Levine, B A, Moir, A J, Audemard, E, Mornet, D, Patchell, V B, Perry, S V

“…The interaction between actin and caldesmon that is associated with the inhibition of actomyosin ATPase activity in smooth muscle has been studied using 1H-NMR…”
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The Regulatory Effects of Tropomyosin and Troponin-I on the Interaction of Myosin Loop Regions with F-actin by Patchell, Valerie B., Gallon, Clare E., Evans, James S., Gao, Yuan, Perry, S. Victor, Levine, Barry A.

“…The N terminus of skeletal myosin light chain 1 and the cardiomyopathy loop of human cardiac myosin have been shown previously to bind to actin in the presence…”
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Phosphorylation of chicken gizzard myosin and the Ca super(2+)-sensitivity of the actin-activated Mg super(2+)-ATPase by Cole, HA, Patchell, V B, Perry, S V

“…A method is described for the preparation of partially and fully phosphorylated chicken gizzard myosin. When fully phosphorylated it possessed an…”
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The inhibitory region of troponin‐I alters the ability of F‐actin to interact with different segments of myosin by Patchell, Valerie B., Gallon, Clare E., Hodgkin, Matthew A., Fattoum, Abdellatif, Perry, S. Victor, Levine, Barry A.

“…Peptides corresponding to the N‐terminus of skeletal myosin light chain 1 (rsMLC1 1–37) and the short loop of human cardiac β‐myosin (hcM398–414) have been…”
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Phosphorylation of chicken gizzard myosin and the Ca2+‐sensitivity of the actin‐activated Mg2+‐ATPase by Cole, Heather A., Patchell, Valerie B., Perry, S.Victory

“…A method is described for the preparation of partially and fully phosphorylated chicken gizzard myosin. When fully phosphorylated it possessed an…”
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Phosphorylation of the minimal inhibitory region at the C-terminus of caldesmon alters its structural and actin binding properties by Patchell, Valerie B., Vorotnikov, Alexander V., Gao, Yuan, Low, Douglas G., Evans, James S., Fattoum, Abdellatif, El-Mezgueldi, Mohammed, Marston, Steven B., Levine, Barry A.

“…Caldesmon is an inhibitory protein believed to be involved in the regulation of thin filament activity in smooth muscles and is a major cytoplasmic substrate…”
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Structural study of gizzard caldesmon and its interaction with actin by LEVINE, Barry A., MOIR, Arthur J. G., AUDEMARD, Etienne, MORNET, Dominique, PATCHELL, Valerie B., PERRY, S. Victor

“…The interaction between actin and caldesmon that is associated with the inhibition of actomyosin ATPase activity in smooth muscle has been studied using 1H‐NMR…”
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Phosphorylation of chicken gizzard myosin and the Ca 2+-sensitivity of the actin-activated Mg 2+-ATPase by Cole, Heather A., Patchell, Valerie B., Perry, S.Victory

“…A method is described for the preparation of partially and fully phosphorylated chicken gizzard myosin. When fully phosphorylated it possessed an…”
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