Search Results - "Patch, R J"

Mutations in Classical Swine Fever Virus NS4B Affect Virulence in Swine by Fernandez-Sainz, I, Gladue, D.P, Holinka, L.G, O'Donnell, V, Gudmundsdottir, I, Prarat, M.V, Patch, J.R, Golde, W.T, Lu, Z, Zhu, J, Carrillo, C, Risatti, G.R, Borca, M.V

“…NS4B is one of the nonstructural proteins of classical swine fever virus (CSFV), the etiological agent of a severe, highly lethal disease of swine. Protein…”
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Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-10401 and SLA-20401 by Pedersen, L. E., Harndahl, M., Nielsen, M., Patch, J. R., Jungersen, G., Buus, S., Golde, W. T.

“…Summary Characterization of the peptide‐binding specificity of swine leukocyte antigen (SLA) class I and II molecules is critical to the understanding of…”
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Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist by Ferkany, J W, Hamilton, G S, Patch, R J, Huang, Z, Borosky, S A, Bednar, D L, Jones, B E, Zubrowski, R, Willetts, J, Karbon, E W

“…2R,4R,5S-(2-amino-4,5-(1,2-cyclohexyl)-7-phosphonoheptanoic acid) (NPC 17742), the most potent isomer of the mixture…”
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Ifenprodil potently interacts with [3H](+)-3-PPP-labeled sigma binding sites in guinea pig brain membranes by Karbon, E W, Patch, R J, Pontecorvo, M J, Ferkany, J W

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2-Hydroxy-4,6-diamino-[1,3,5]triazines: A Novel Class of VEGF-R2 (KDR) Tyrosine Kinase Inhibitors by Baindur, Nand, Chadha, Naresh, Brandt, Benjamin M, Asgari, Davoud, Patch, Raymond J, Schalk-HiHi, Celine, Carver, Theodore E, Petrounia, Ioanna P, Baumann, Christian A, Ott, Heidi, Manthey, Carl, Springer, Barry A, Player, Mark R

“…2-Hydroxy-4,6-diamino-[1,3,5]triazines are described which are a novel class of potent inhibitors of the VEGF-R2 (flk-1/KDR) tyrosine kinase…”
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(Aminoalkoxy)chromones. Selective .sigma. receptor ligands by Erickson, Ronald H, Natalie, Kenneth J, Bock, William, Lu, Zhijian, Farzin, Farzaneh, Sherrill, Ronald G, Meloni, David J, Patch, Raymond J, Rzesotarski, Waclaw J

“…A series of (aminoalkoxy)chromones has been prepared, members of which bind potently (16-100 nM) at the sigma binding site and bind weakly (greater than 1000…”
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T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection by Clayton, Linda K., Ghendler, Yoseph, Mizoguchi, Emiko, Patch, Raymond J., Ocain, Timothy D., Orth, Kim, Bhan, Atul K., Dixit, Vishva M., Reinherz, Ellis L.

“…T‐cell receptors (TCRs) are created by a stochastic gene rearrangement process during thymocyte development, generating thymocytes bearing useful, as well as…”
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Substituted 2-(aminomethyl)piperidines: a novel class of selective protein kinase C inhibitors by Shearer, Barry G, Sullivan, James P, Carter, J. Paul, Mathew, Rose M, Waid, Phillip, Connor, Jane R, Patch, Raymond J, Burch, Ronald M

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Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents by Pontecorvo, M J, Karbon, E W, Goode, S, Clissold, D B, Borosky, S A, Patch, R J, Ferkany, J W

“…The recent finding that ifenprodil binds with high affinity to sigma sites suggests that other sigma agents may have ifenprodil-like cerebroprotectant and…”
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Asymmetric synthesis of a potent and selective competitive NMDA antagonist by Hamilton, Gregory S, Huang, Zhiwen, Yang, Xiao Jing, Patch, Raymond J, Narayanan, B. A, Ferkany, John W

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Stereostructure-activity relationships of the GABA-containing cis-decahydroquinoline-5-carboxylic acids; intracerebroventricular studies in mice by Fung, Y K, Bero, C, Dircks, D, Tomita, K, Patch, R J, Witiak, D T

“…Two cis-decahydroquinoline-5-carboxylic acids, cis-1 and 2 were investigated for their pharmacological activities in vivo. Intracerebroventricular…”
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A Tandem Heck-Carbocyclization/Suzuki-Coupling Approach to the Stereoselective Syntheses of Asymmetric 3,3-(Diarylmethylene)indolinones by Cheung, Wing S, Patch, Raymond J, Player, Mark R

“…An efficient and versatile method for stereoselective synthesis of (E)-3,3-(diarylmethylene)indolinones by a palladium-catalyzed tandem…”
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Stereoselective syntheses of the trans-decahydroquinoline-5-carboxylic acid epimers. Diastereomeric zwitterionic probes of .gamma.-aminobutyric acid-related biological properties in vitro and in vivo by Witiak, Donald T, Patch, Raymond J, Enna, S. J, Fung, Yiu K

“…The syntheses of the 5 beta and 5 alpha epimers of trans-(4a alpha,8a beta)-decahydroquinoline-5-carboxylic acids (3 and 4) from vinylogous bicyclic imide 10…”
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Single-Step Syntheses of 2-Amino-7-chlorothiazolo[5,4-d]pyrimidines:  Intermediates for Bivalent Thiazolopyrimidines by Liu, Jian, Patch, Raymond J, Schubert, Carsten, Player, Mark R

“…A single-step process for the preparation of 2-amino-7-chlorothiazolo[5,4-d]pyrimidines, 2, was achieved by the reaction of the commercially available…”
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Neopentyl ester protecting groups for arylsulfonic acids by Roberts, John C., Gao, Huai, Gopalsamy, Ariamala, Kongsjahju, Azis, Patch, Raymond J.

“…We report that neopentylsulfonate esters are stable to a variety of standard organic reaction conditions and are easily cleaved to sulfonic acids. We also…”
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Multivalent Templated Saccharides:  Convenient Syntheses of Spacer-Linked 1,1‘-Bis -and 1,1‘,1‘‘-Tris-β-glycosides by the Glycal Epoxide Glycosidation Method by Patch, Raymond J, Chen, Hang, Pandit, Chennagiri R

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Effect of wavelet processing on stratigraphic resolution by Rives, R. G., Patch, J. R.

“…Wavelet processing has proved to be a viable technique for improving the resolution and character of seismic events. Substantial improvement in signal-to-noise…”
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Lipophilic bis-arylsulfonates as inhibitors of the CD4-gp120 interaction by Patch, Raymond J., Roberts, John C., Huai Gao, Zhan Shi, Gopalsamy, Ariamala, Kongsjahju, Azis, Daniels, Kevin, Kowalczyk, Paul J., van Schravendijk, Marie-Rose, Gordon, Kristin A., Pallai, Peter V.

“…A series of lipophilic bis-arylsulfonates was synthesized and evaluated as potential inhibitors of the CD4-gp120 interaction. Structure-activity studies…”
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Epimeric cis-decahydroquinoline-5-carboxylic acids: effects on .gamma.-aminobutyric acid uptake and receptor binding in vitro by Witiak, Donald T, Tomita, Kuniyuki, Patch, Raymond J, Enna, S. J

“…The syntheses for two cis-decahydroquinoline-5-carboxylic acid epimers (1 and 2) which contain the =N(C)3CO2H (gamma-aminobutyric acid; GABA) moiety are…”
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