Search Results - "Patarroyo, M.E."

Quantum chemical analysis of MHC-peptide interactions for vaccine design by Agudelo, W A, Patarroyo, M E

“…The development of an adequate immune response against pathogens is mediated by molecular interactions between different cell types. Among them, binding of…”
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Potent, long lasting systemic antibody levels and mixed Th1/Th2 immune response after nasal immunization with malaria antigen loaded PLGA microparticles by Carcaboso, A.M, Hernández, R.M, Igartua, M, Rosas, J.E, Patarroyo, M.E, Pedraz, J.L

“…The immunogenicity of the synthetic malaria vaccine SPf66 has been recently improved by the application of new adjuvants as QS-21 saponin or poly- d,…”
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Structural Modifications Enable Conserved Peptides to Fit into MHC Molecules thus Inducing Protection against Malaria by Patarroyo, Manuel Elkin, Cifuentes, Gladys, Vargas, Luis Eduardo, Rosas, Jaiver

“…High‐activity binding peptides (left) that have been chemically modified in specific places so that they fitted into the MHC class II T‐cell receptor complex…”
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Immunization of cattle with synthetic peptides derived from the Boophilus microplus gut protein (Bm86) by Patarroyo, J.H, Portela, R.W, De Castro, R.O, Couto Pimentel, J, Guzman, F, Patarroyo, M.E, Vargas, M.I, Prates, A.A, Dias Mendes, M.A

“…Three synthetic peptides (SBm4912, SBm7462 and SBm19733), derived from the Bm86 glycoprotein from Boophilus microplus gut, were constructed and used to…”
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Prevalence of infection with high-risk human papillomavirus in women in Colombia by Soto-De Leon, S.C., Camargo, M., Sanchez, R., Leon, S., Urquiza, M., Acosta, J., Monsalve, D., Rodriguez, L.E., Patarroyo, M.E., Patarroyo, M.A.

“…The prevalence of human papillomavirus (HPV) infections in 2109 females inhabiting five cities of Colombia was determined. Of the 49.2% with an HPV infection,…”
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Alpha helix shortening in 1522 MSP-1 conserved peptide analogs is associated with immunogenicity and protection against P. falciparum malaria by Cubillos, Marcia, Espejo, Fabiola, Purmova, Jindra, Martinez, Juan C., Patarroyo, M.E.

“…1522 is a nonimmunogenic conserved high‐activity binding peptide (HABP) belonging to Plasmodium falciparum MSP‐1 protein N‐terminal fragment. The key amino…”
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Immune response in mice and cattle after immunization with a Boophilus microplus DNA vaccine containing bm86 gene by Ruiz, Lina María, Orduz, Sergio, López, Elkin D., Guzmán, Fanny, Patarroyo, Manuel E., Armengol, Gemma

“…Plasmid pBMC2 encoding antigen Bm86 from a Colombian strain of cattle tick Boophilus microplus, was used for DNA-mediated immunization of BALB/c mice,…”
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Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research by Daubenberger, Claudia A., Spirig, Rolf, Patarroyo, Manuel E., Pluschke, Gerd

“…The reactivity of 204 monoclonal antibodies (mAb) out of 377 commercially available antibodies collected by the animal homologue group of the HLAD8 was…”
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Immune response after oral administration of the encapsulated malaria synthetic peptide SPf66 by Carcaboso, A.M., Hernández, R.M., Igartua, M., Gascón, A.R., Rosas, J.E., Patarroyo, M.E., Pedraz, J.L.

“…The synthetic peptide SPf66 adsorbed on alum is one of the few Plasmodium falciparum vaccines which have been tested in field trials. We previously reported…”
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Immunological and structural characterization of an epitope from the Trypanosoma cruzi KMP-11 protein by Díez, H., Guzmán, F., Alba, M.P., Cuéllar, A., Thomas, M.C., López, M.C., Rosas, F., Velasco, V., González, J.M., Patarroyo, M.E., Puerta, C.J.

“…The K1 peptide is an HLA-A*0201-restricted cytotoxic epitope derived from the Trypanosoma cruzi KMP-11 protein, this being the etiological agent of Chagas’…”
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Remarkably high antibody levels and protection against P. falciparum malaria in Aotus monkeys after a single immunisation of SPf66 encapsulated in PLGA microspheres by Rosas, J.E, Pedraz, J.L, Hernández, R.M, Gascón, A.R, Igartua, M, Guzmán, F, Rodrı́guez, R, Cortés, J, Patarroyo, M.E

“…Single dose immunisation is a major goal in vaccine design. The purpose of this study was the development of a single dose delivery system for the SPf66…”
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Biodegradable PLGA microspheres as a delivery system for malaria synthetic peptide SPf66 by Rosas, J.E., Hernández, R.M., Gascón, A.R., Igartua, M., Guzman, F., Patarroyo, M.E., Pedraz, J.L.

“…SPf66 is the first chemically synthesised vaccine to elicit a partial protective immune response against malaria. The aluminium hydroxide (alum)-adsorbed SPf66…”
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Synthetic peptides from Plasmodium falciparum apical membrane antigen 1 (AMA-1) specifically interacting with human hepatocytes by Valbuena, J., Rodríguez, L., Vera, R., Puentes, A., Curtidor, H., Cortés, J., Rosas, J., Patarroyo, M.E.

“…Plasmodium falciparum apical membrane antigen 1 (AMA-1) is expressed during both the sporozoite and merozoite stage of the parasite's life cycle. The role…”
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Plasmodium falciparum acid basic repeat antigen (ABRA) peptides: erythrocyte binding and biological activity by Curtidor, H, Urquiza, M, Suarez, J.E, Rodriguez, L.E, Ocampo, M, Puentes, A, Garcia, J.E, Vera, R, Lopéz, R, Ramirez, L.E, Pinzon, M, Patarroyo, M.E

“…Non overlapping 20-mer peptides, covering the complete sequence of acid basic repeat antigen (ABRA) of Plasmodium falciparum, were synthesised and tested in…”
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Isolation and identification of mycobacteria in New World primates maintained in captivity by Alfonso, R, Romero, R.E, Diaz, A, Calderon, M.N, Urdaneta, G, Arce, J, Patarroyo, M.E, Patarroyo, M.A

“…The presence of several Mycobacterium species was determined in 68 New World monkeys kept captive in the Cali Zoo. One hundred and thirty-three gastric lavage…”
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Vaccination with SPf66, a chemically synthesised vaccine, against Plasmodium falciparum malaria in Colombia by Valero, M V, Amador, L R, Galindo, C, Figueroa, J, Bello, M S, Murillo, L A, Mora, A L, Patarroyo, G, Rocha, C L, Rojas, M

“…Preclinical and clinical studies have established the safety and immunogenicity of the chemically synthesised SPf66 malaria vaccine. The present study is a…”
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MSP-1 malaria pseudopeptide analogs: biological and immunological significance and three-dimensional structure by Lozano, José Manuel, Alba, Martha Patricia, Vanegas, Magnolia, Silva, Yolanda, Torres-Castellanos, José Libardo, Patarroyo, Manuel Elkin

“…Merozoite Surface Protein-1 (MSP-1) has been considered as a malaria vaccine candidate. It is processed during the Plasmodium falciparum invasion process of…”
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Amplification of a 500-base-pair fragment from cultured isolates of Mycobacterium bovis by Rodriguez, J.G, Fissanoti, J.C, Portillo, P.D, Patarroyo, M.E, Romano, M.I, Cataldi, A

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evaluation of SPf66 malaria vaccine during a 22-month follow-up field trial in the Pacific coast of Colombia by Valero, M.V., Amador, R., Aponte, J.J., Narvaez, A., Galindo, C., Silva, Y., Rosas, J., Guzman, F., Patarroyo, M.E.

“…A double-blind randomized placebo-controlled field trial with the SPf66 malaria vaccine was carried out in an endemic area consisting of 14 small villages with…”
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Two MSA 2 peptides that bind to human red blood cells are relevant to Plasmodium falciparum merozoite invasion by Ocampo, M., Urquiza, M., Guzmán, F., Rodriguez, L.E., Suarez, J., Curtidor, H., Rosas, J., Diaz, M., Patarroyo, M.E.

“…: Plasmodium falciparum merozoite membrane surface antigen 2 (MSA 2) has been associated with the development of protective immunity against malaria. MSA 2…”
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