Search Results - "Pasunooti, Swathi"
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Enzymatic synthesis of c-di-GMP using a thermophilic diguanylate cyclase
Published in Analytical biochemistry (15-06-2009)“…The cyclic dinucleotide c-di-GMP is a widespread bacterial messenger molecule with potential application as a therapeutic agent for treating bacterial…”
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Solution Structure of the PAS Domain of a Thermophilic YybT Protein Homolog Reveals a Potential Ligand-binding Site
Published in The Journal of biological chemistry (26-04-2013)“…The Bacillus subtilis protein YybT (or GdpP) and its homologs were recently established as stress signaling proteins that exert their biological effect by…”
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HflX is a GTPase that controls hypoxia-induced replication arrest in slow-growing mycobacteria
Published in Proceedings of the National Academy of Sciences - PNAS (23-03-2021)“…GTPase high frequency of lysogenization X (HflX) is highly conserved in prokaryotes and acts as a ribosome-splitting factor as part of the heat shock response…”
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Sol–gel immobilization of a thermophilic diguanylate cyclase for enzymatic production of cyclic-di-GMP
Published in Journal of molecular catalysis. B, Enzymatic (01-11-2010)“…[Display omitted] ▶ Sol–gel immobilized diguanylate cyclase exhibits enhanced stability. ▶ Synthesis of c-di-GMP by immobilized diguanylate cyclase. ▶…”
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2a super(2),3a super(2)-cAMP hydrolysis by metal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screening
Published in Biochemical and biophysical research communications (30-07-2010)“…The recent report of 2a super(2),3a super(2)-cAMP isolated from rat kidney is the first proof of its biological existence, which revived interest in this…”
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2′,3′-cAMP hydrolysis by metal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screening
Published in Biochemical and biophysical research communications (30-07-2010)“…► 2′,3′-cAMP can be hydrolyzed into 3′-AMP by six PDEs with known substrates. ► Catalytic efficiency of 2′,3′-cAMP and bis-pNPP hydrolysis correlates. ►…”
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