Search Results - "Pasukoniene, Vita"

Immunomodulatory properties of bacteriophage derived dsRNA of different size and their use as anticancer vaccine adjuvants by Dobrovolskienė, Neringa, Balevičius, Ramojus, Mlynska, Agata, Žilionytė, Karolina, Aleksander Krasko, Jan, Strioga, Marius, Lieknina, Ilva, Pjanova, Dace, Pašukonienė, Vita

“…Dendritic cell (DC) based immunotherapy is one of the strategies to combat cancer invoking a patient's immune system. This form of anticancer immunotherapy…”
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Functional antigen processing and presentation mechanism as a prerequisite factor of response to treatment with dendritic cell vaccines and anti-PD-1 in preclinical murine LLC1 and GL261 tumor models by Žilionytė, Karolina, Bagdzevičiūtė, Ugnė, Mlynska, Agata, Urbštaitė, Elena, Paberalė, Emilija, Dobrovolskienė, Neringa, Krasko, Jan Aleksander, Pašukonienė, Vita

“…Low efficacy of cancer immunotherapy encourages the search for possible resistance mechanisms and biomarkers that would predict the outcome of immunotherapy in…”
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Letter to the Editor: No immunophenotyping in peripheral blood of prostate cancer patients treated with neoadjuvant Rituximab? by Bosas, Paulius, Zaleskis, Gintaras, Pasukoniene, Vita, Jankevicius, Feliksas

“…[...]the double positive CD20+CD3+ lymphocyte was demonstrated to be a specific marker of therapeutic response in rheumatoid arthritis patients receiving Rx…”
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Prognostic significance of soluble PD-L1 in prostate cancer by Zvirble, Margarita, Survila, Zilvinas, Bosas, Paulius, Dobrovolskiene, Neringa, Mlynska, Agata, Zaleskis, Gintaras, Jursenaite, Jurgita, Characiejus, Dainius, Pasukoniene, Vita

“…The aim of this study was to assess the role of sPD-L1 and sPD-1 as potential biomarkers in prostate cancer (PCa). The association of the values of these…”
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Do the benefits of being a smoker hint at the existence of PD-1/PD-L1 sensitizers for patients on single-agent immunotherapy? by Zaleskis, Gintaras, Pasukoniene, Vita, Characiejus, Dainius, Urbonas, Vincas

“…Multiple studies demonstrate significantly better therapeutics outcomes in smokers as compared with never smokers when single-agent immunotherapy is applied…”
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A gene signature for immune subtyping of desert, excluded, and inflamed ovarian tumors by Mlynska, Agata, Vaišnorė, Ramunė, Rafanavičius, Vytautas, Jocys, Simonas, Janeiko, Julija, Petrauskytė, Monika, Bijeikis, Simas, Cimmperman, Piotras, Intaitė, Birutė, Žilionytė, Karolina, Barakauskienė, Aušrinė, Meškauskas, Raimundas, Paberalė, Emilija, Pašukonienė, Vita

“…Problem The current tumor immunology paradigm emphasizes the role of the immune tumor microenvironment and distinguishes several histologically and…”
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A Refinement of Clinical Tumor Marker Monitoring: Why Not Use an Inverse Value of Doubling Time? by Zaleskis, Gintaras, Bosas, Paulius, Ulys, Albertas, Dabkevičiene, Daiva, Dobrovolskiene, Neringa, Hudson, Bret Andrew, Pašukoniene, Vita

“…Objectives: The aim of this study was to compare prostate-specific antigen (PSA) kinetics – half-life time (HT), doubling time (DT), and elimination rate PSA…”
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Doxorubicin uptake in ascitic lymphoma model: resistance or curability is governed by tumor cell density and prolonged drug retention by Zaleskis, Gintaras, Garberytė, Sima, Pavliukevičienė, Božena, Valinčius, Gintaras, Characiejus, Dainius, Mauricas, Mykolas, Kraśko, Jan Aleksander, Žilionytė, Karolina, Žvirblė, Margarita, Pašukonienė, Vita

“…Background/Aims: Chemotherapy resistance of malignancies is a universal phenomenon which unfavorably affects therapeutic results. Genetic adaptations as well…”
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CD8(high)CD57(+) T-cell population as an independent predictor of response to chemoradiation therapy in extensive-stage small cell lung cancer by Dobrovolskienė, Neringa T, Cicėnas, Saulius, Kazlauskaitė, Nijolė, Mišeikytė-Kaubrienė, Edita, Krasko, Jan A, Ostapenko, Valerijus, Pašukonienė, Vita, Strioga, Marius M

“…Tangible clinical benefit is achieved in only a relatively small proportion of extensive-stage small cell lung cancer (SCLC) patients receiving current…”
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Post-operative unadjuvanted therapeutic xenovaccination with chicken whole embryo vaccine suppresses distant micrometastases and prolongs survival in a murine Lewis lung carcinoma model by Kraśko, Jan Aleksander, Žilionytė, Karolina, Darinskas, Adas, Dobrovolskienė, Neringa, Mlynska, Agata, Riabceva, Svetlana, Zalutsky, Iosif, Derevyanko, Marina, Kulchitsky, Vladimir, Karaman, Olga, Fedosova, Natalia, Symchych, Tatiana Vasyliyvna, Didenko, Gennady, Chekhun, Vasyl, Strioga, Marius, Pašukonienė, Vita

“…Immunotherapy in the form of anticancer vaccination relies on the mobilization of the patient's immune system against specific cancer antigens. Instead of…”
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CD8+ CD28− and CD8+ CD57+ T cells and their role in health and disease by Strioga, Marius, Pasukoniene, Vita, Characiejus, Dainius

“…Summary Chronic antigenic stimulation leads to gradual accumulation of late‐differentiated, antigen‐specific, oligoclonal T cells, particularly within the CD8+…”
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Accumulation and biological effects of cobalt ferrite nanoparticles in human pancreatic and ovarian cancer cells by Pašukonienė, Vita, Mlynska, Agata, Steponkienė, Simona, Poderys, Vilius, Matulionytė, Marija, Karabanovas, Vitalijus, Statkutė, Urtė, Purvinienė, Rasa, Kraśko, Jan Aleksander, Jagminas, Arūnas, Kurtinaitienė, Marija, Strioga, Marius, Rotomskis, Ričardas

“…Superparamagnetic iron oxide nanoparticles (SPIONs) emerge as a promising tool for early cancer diagnostics and targeted therapy. However, both toxicity and…”
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Bacterial ghosts as adjuvants in syngeneic tumour cell lysate-based anticancer vaccination in a murine lung carcinoma model by Kraśko, Jan Aleksander, Žilionytė, Karolina, Darinskas, Adas, Strioga, Marius, Rjabceva, Svetlana, Zalutsky, Iosif, Derevyanko, Marina, Kulchitsky, Vladimir, Lubitz, Werner, Kudela, Pavol, Miseikyte-Kaubriene, Edita, Karaman, Olha, Didenko, Hennadii, Potebnya, Hryhorii, Chekhun, Vasyl, Pašukonienė, Vita

“…Instead of relying on external anticancer factors for treatment, immunotherapy utilizes the hosts own immune system and directs it against given tumour…”
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Defining Melanoma Immune Biomarkers-Desert, Excluded, and Inflamed Subtypes-Using a Gene Expression Classifier Reflecting Intratumoral Immune Response and Stromal Patterns by Mlynska, Agata, Gibavičienė, Jolita, Kutanovaitė, Otilija, Senkus, Linas, Mažeikaitė, Julija, Kerševičiūtė, Ieva, Maskoliūnaitė, Vygantė, Rupeikaitė, Neda, Sabaliauskaitė, Rasa, Gaiževska, Justina, Suveizdė, Karolina, Kraśko, Jan Aleksander, Dobrovolskienė, Neringa, Paberalė, Emilija, Žymantaitė, Eglė, Pašukonienė, Vita

“…The spatial distribution of tumor infiltrating lymphocytes (TILs) defines several histologically and clinically distinct immune subtypes-desert (no TILs),…”
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A method to estimate cell cycle time and growth fraction using bromodeoxyuridine-flow cytometry data from a single sample by Eidukevicius, Rimantas, Characiejus, Dainius, Janavicius, Ramunas, Kazlauskaite, Nijole, Pasukoniene, Vita, Mauricas, Mykolas, Den Otter, Willem

“…Presently available flow cytometric methods of bromodeoxyuridine (BrdUrd) labelling do not provide information on the cell cycle time (TC) and the growth…”
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Correction: a method to estimate cell cycle time and growth fraction using bromodeoxyuridine-flow cytometry data from a single sample by Eidukevicius, Rimantas, Characiejus, Dainius, Janavicius, Ramunas, Kazlauskaite, Nijole, Pasukoniene, Vita, Mauricas, Mykolas, Den Otter, Willem

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Evaluation of low-dose proton beam radiation efficiency in MIA PaCa-2 pancreatic cancer cell line vitality and H2AX formation by Liubavičiūtė, Aušra, Kraśko, Jan Aleksander, Mlynska, Agata, Lagzdina, Jelena, Sužiedėlis, Kęstutis, Pašukonienė, Vita

“…The aim of this study was to evaluate the efficiency of proton beam irradiation in pancreatic cancer cell line MIA PaCa-2 and its role in the cell cycle,…”
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Immunophenotype Rearrangement in Response to Tumor Excision May Be Related to the Risk of Biochemical Recurrence in Prostate Cancer Patients by Bosas, Paulius, Zaleskis, Gintaras, Dabkevičiene, Daiva, Dobrovolskiene, Neringa, Mlynska, Agata, Tikuišis, Renatas, Ulys, Albertas, Pašukoniene, Vita, Jarmalaitė, Sonata, Jankevičius, Feliksas

“…Background: Prostate cancer (PCa) is known to exhibit a wide spectrum of aggressiveness and relatively high immunogenicity. The aim of this study was to…”
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Role of marker lesion when applying intravesical instillations of IL-2 for non-muscle-invasive bladder cancer comparison of the therapeutic effects in two pilot studies by Den Otter, Willem, Van Moorselaar, R Jeroen, Jacobs, John J L, Haar, Ronald Ter, Koten, Jan W, Dobrowolski, Zygmunt, Lipczynski, Waclaw, Pašukonienė, Vita, Characiejus, Dainius, Jankevičius, Feliksas, Eidukevičius, Rimantas, De Reijke, Theo M

“…Comparison of the therapeutic effect of treatment of non-muscle invasive bladder carcinoma (NMIBC) after intravesical Interleukin-2 (IL-2) instillations in the…”
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Prediction of Response in Cancer Immunotherapy by CHARACIEJUS, Dainius, JACOBS, John J. L, PASUKONIENE, Vita, KAZLAUSKAITE, Nijolė, DANILEVICIUTE, Vita, MAURICAS, Mykolas, DEN OTTER, Willem

“…This review focuses on the relationship between pre-treatment immune parameter values and outcome of immunotherapy of cancer patients. The evidence presented…”
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