Search Results - "Pastrana, Belinda"

The structure, molecular dynamics, and energetics of centrin-melittin complex by Sosa, Liliana del Valle, Alfaro, Elisa, Santiago, Jorge, Narváez, Daniel, Rosado, Marie Cely, Rodríguez, Aslin, Gómez, Ana María, Schreiter, Eric R., Pastrana-Ríos, Belinda

“…Centrin is a calcium binding protein (CaBP) belonging to the EF‐hand superfamily. As with other proteins within this family, centrin is a calcium sensor with…”
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Relative Stability of Human Centrins and Its Relationship to Calcium Binding by Pastrana-Ríos, Belinda, Reyes, Myrna, De Orbeta, Jessica, Meza, Verónica, Narváez, Daniel, Gómez, Ana María, Rodríguez Nassif, Aslin, Almodovar, Ruth, Díaz Casas, Adalberto, Robles, José, Ortiz, Ana María, Irizarry, Lizbeth, Campbell, Melissa, Colón, Mara

“…Centrins are calcium binding proteins that belong to the EF-hand superfamily with diverse biological functions. Herein we present the first systematic study…”
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Real-time monitoring of trehalose crystallization using quantum cascade laser microscopy and 2D-COS by Acevedo Rivera, Yesenia M., Meléndez, Michael, Pastrana-Ríos, Belinda

“…Molecular detail of the trehalose crystallization process was obtained during thermal perturbation through real-time monitoring using a Quantum Cascade Laser…”
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Prp40 Homolog A Is a Novel Centrin Target by Díaz Casas, Adalberto, Chazin, Walter J., Pastrana-Ríos, Belinda

“…Pre-mRNA processing protein 40 (Prp40) is a nuclear protein that has a role in pre-mRNA splicing. Prp40 possesses two leucine-rich nuclear export signals, but…”
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Trifluoroacetic acid as excipient destabilizes melittin causing the selective aggregation of melittin within the centrin-melittin-trifluoroacetic acid complex by Pastrana-Rios, Belinda, Del Valle Sosa, Liliana, Santiago, Jorge

“…Trifluoroacetic acid (TFA) may be the cause of the bottleneck in high resolution structure determination for protein-peptide complexes. Fragment based drug…”
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Calcium titration of Chlamydomonas reinhardtii centrin and its structural changes by Ocana, Wanda, Pastrana-Rios, Belinda

“…•2D IR correlation spectroscopy study has proven useful in the study of CaBP’s.•Comparative analysis of the molecular behavior of centrin and its terminal…”
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Molecular biophysical characterization of the third FF domain of Homo sapiens Prp40 homolog A by Díaz Casas, Adalberto, Casanova Sepúlveda, Gabriela, Sánchez Negrón, Odalys, Caro Muñiz, Andrea P., Malavé Ramos, Stewart R., Cebollero López, Ana R., Pastrana-Ríos, Belinda

“…Homo sapiens Prp40 Homolog A (HsPrp40A) is a nuclear protein that is involved in pre-mRNA splicing. This modular protein has two WW domains followed by six…”
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Developability Assessment of an Isolated CH2 Immunoglobulin Domain by Pastrana, Belinda, Nieves, Sherly, Li, Wei, Liu, Xianglei, Dimitrov, Dimiter S

“…The IgG CH2 domain continues to hold promise for the development of new therapeutic entities because of its bifunctional role as a biomarker and effector…”
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Streamlined Multi-Attribute Assessment of an Array of Clinical-Stage Antibodies: Relationship Between Degradation and Stability by Pastrana, Belinda, Culyba, Elizabeth, Nieves, Sherly, Sazinsky, Stephen L, Canto, Eduardo I, Noda, Isao

“…Clinical antibodies are an important class of drugs for the treatment of both chronic and acute diseases. Their manufacturability is subject to evaluation to…”
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Developability Assessment of an Isolated C H 2 Immunoglobulin Domain by Pastrana, Belinda, Nieves, Sherly, Li, Wei, Liu, Xianglei, Dimitrov, Dimiter S

“…The IgG C 2 domain continues to hold promise for the development of new therapeutic entities because of its bifunctional role as a biomarker and effector…”
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Mechanism of Unfolding of a Model Helical Peptide by Pastrana-Rios, Belinda

“…Synthetic model helical peptides, Acetyl-W(EAAAR)5A-amide with 13CO specifically labeled alanine segments in repeats n = 1,2 or 4,5 were studied in aqueous…”
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Crystallization and preliminary X-ray characterization of full-length Chlamydomonas reinhardtii centrin by Alfaro, Elisa, Sosa, Liliana del Valle, Sanoguet, Zuleika, Pastrana-Ríos, Belinda, Schreiter, Eric R.

“…Chlamydomonas reinhardtii centrin is a member of the EF‐hand calcium‐binding superfamily. It is found in the basal body complex and is important for flagellar…”
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The Kinetics of the Hydrogen/Deuterium Exchange of Epidermal Growth Factor Receptor Ligands by Iloro, Ibon, Narváez, Daniel, Guillén, Nancy, Camacho, Carlos M., Guillén, Lalisse, Cora, Elsa, Pastrana-Ríos, Belinda

“…Five highly homologous epidermal growth factor receptor ligands were studied by mass spectral analysis, hydrogen/deuterium (H/D) exchange via attenuated total…”
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Breakthrough Empirical Approach to Determining Deamidation Sites and Assessing Protein Stability for an Array of Therapeutic Proteins in Solution by Pastrana-Rios, Belinda

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Mechanism of Unfolding of A Model Helical Peptide by Pastrana-Rios, Belinda, Lopez, Gustavo

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Cloning of a Novel Centrin Target Peptide by Rodriguez, Aslin M., Gomez, Ana M., Pastrana, Belinda

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Secondary Structure Changes in a Calcium Binding Protein: Centrin by Pastrana-Rios, Belinda, Medina, Zuleika, Ocana, Wanda

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Water soluble molybdenocene complexes: Synthesis, cytotoxic activity and binding studies to ubiquitin by fluorescence spectroscopy, circular dichroism and molecular modeling by Narváez-Pita, Xiomara, Ortega-Zuniga, Carlos, Acevedo-Morantes, Claudia Y., Pastrana, Belinda, Olivero-Verbel, Jesus, Maldonado-Rojas, Wilson, Ramírez-Vick, Jaime E., Meléndez, Enrique

“…Four new molybdenocene complexes, Cp2Mo(l-ascorbato), Cp2Mo(6-O-palmitoyl-l-ascorbato), [Cp2Mo(ethyl maltolato)]Cl and…”
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Comparative Biophysical Analysis of Centrosomal Proteins and Their Complexes by Sosa, Liliana D.V., Narvaez, Daniel, Gomez, Ana M., Pastrana, Belinda

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Thermal perturbation correlation of calcium binding Human centrin 3 and its structural changes by Pastrana-Rios, Belinda

“…•PCMW2D correlation spectroscopy has proven useful in defining Tm of protein motifs.•The aspartates and glutamates vibrational modes were analyzed.•The…”
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