Search Results - "Pastor, Núria"

Collecting duct intercalated cell function and regulation by Roy, Ankita, Al-bataineh, Mohammad M, Pastor-Soler, Núria M

“…Intercalated cells are kidney tubule epithelial cells with important roles in the regulation of acid-base homeostasis. However, in recent years the…”
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Intercalated Cells of the Kidney Collecting Duct in Kidney Physiology by Rao, Renee, Bhalla, Vivek, Pastor-Soler, Núria M.

“…The epithelium of the kidney collecting duct (CD) is composed mainly of two different types of cells with distinct and complementary functions. CD principal…”
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Depressive symptom severity is a major risk factor for frailty in community-dwelling older adults with depression. A prospective study by Oyon, Joaquim, Serra-Prat, Mateu, Limon, Esther, Ferrer, Mariona, Pastor, Núria, Palomera, Elisabet, Burdoy, Emili

“…Depression and frailty are closely related, but the mechanisms by which depressed older adults are at an increased risk of becoming frail are still not well…”
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Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase by Gidon, Alexandre, Al-Bataineh, Mohammad M, Jean-Alphonse, Frederic G, Stevenson, Hilary P, Watanabe, Tomoyuki, Louet, Claire, Khatri, Ashok, Calero, Guillermo, Pastor-Soler, Núria M, Gardella, Thomas J, Vilardaga, Jean-Pierre

“…A GPCR, the parathyroid hormone receptor, can elicit a sustained signal from internal membranes after internalization. The signal was found to be terminated by…”
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Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease by Li, Hui, Satriano, Joseph, Thomas, Joanna L, Miyamoto, Satoshi, Sharma, Kumar, Pastor-Soler, Núria M, Hallows, Kenneth R, Singh, Prabhleen

“…Renal hypoxia contributes to chronic kidney disease (CKD) progression, as validated in experimental and human CKD. In the early stages, increased oxygen…”
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Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy by Morrell, Eric D, Kellum, John A, Pastor-Soler, Núria M, Hallows, Kenneth R

“…The most common cause of acute kidney injury (AKI) in hospitalized patients is sepsis. However, the molecular pathways and mechanisms that mediate septic AKI…”
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SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states by Banerjee, Sanjay K., McGaffin, Kenneth R., Pastor-Soler, Núria M., Ahmad, Ferhaan

“…Aims Cardiac myocytes depend on a delicate balance of glucose and free fatty acids as energy sources, a balance that is disrupted in pathological states such…”
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Psychosocial factors associated with frailty in the community-dwelling aged population with depression. A cross-sectional study by Oyon, Joaquim, Serra-Prat, Mateu, Ferrer, Mariona, Llinares, Antònia, Pastor, Núria, Limón, Esther, Rejón, Tatiana, Ramírez, Sara, Salietti, Alba

“…There is a two-way relationship between frailty and depression, but the mechanisms by which one may influence the other are not well understood. The objective…”
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Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase by Gong, Fan, Alzamora, Rodrigo, Smolak, Christy, Li, Hui, Naveed, Sajid, Neumann, Dietbert, Hallows, Kenneth R, Pastor-Soler, Núria M

“…The vacuolar H(+)-ATPase (V-ATPase) in type A kidney intercalated cells is a major contributor to acid excretion in the collecting duct. The mechanisms of…”
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Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney by Christensen, Michael, Jensen, Jonas B., Jakobsen, Steen, Jessen, Niels, Frøkiær, Jørgen, Kemp, Bruce E., Marciszyn, Allison L., Li, Hui, Pastor-Soler, Núria M., Hallows, Kenneth R., Nørregaard, Rikke

“…The type-2 diabetes drug metformin has proven to have protective effects in several renal disease models. Here, we investigated the protective effects in a…”
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AMP-activated protein kinase regulation of kidney tubular transport by Pastor-Soler, Núria M, Hallows, Kenneth R

“…PURPOSE OF REVIEWThe coupling of epithelial transport to underlying metabolic status is critical because solute transport processes normally consume a large…”
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Muc1 is protective during kidney ischemia-reperfusion injury by Pastor-Soler, Núria M, Sutton, Timothy A, Mang, Henry E, Kinlough, Carol L, Gendler, Sandra J, Madsen, Cathy S, Bastacky, Sheldon I, Ho, Jacqueline, Al-Bataineh, Mohammad M, Hallows, Kenneth R, Singh, Sucha, Monga, Satdarshan P, Kobayashi, Hanako, Haase, Volker H, Hughey, Rebecca P

“…Ischemia-reperfusion injury (IRI) due to hypotension is a common cause of human acute kidney injury (AKI). Hypoxia-inducible transcription factors (HIFs)…”
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Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase by Wang, Zhijian, Subramanya, Arohan R, Satlin, Lisa M, Pastor-Soler, Núria M, Carattino, Marcelo D, Kleyman, Thomas R

“…Large-conductance, Ca(2+)-activated K(+) channels, commonly referred to as BK channels, have a major role in flow-induced K(+) secretion in the distal nephron…”
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Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice by Hallows, Kenneth R, Li, Hui, Saitta, Biagio, Sepehr, Saman, Huang, Polly, Pham, Jessica, Wang, Jonathan, Mancino, Valeria, Chung, Eun Ji, Pinkosky, Stephen L, Pastor-Soler, Núria M

“…ADPKD has few therapeutic options. Tolvaptan slows disease but has side effects limiting its tolerability. Bempedoic acid (BA), an ATP citrate-lyase (ACLY)…”
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Remote Monitoring Telemedicine (REMOTE) Platform for Patients With Anxiety Symptoms and Alcohol Use Disorder: Protocol for a Case-Control Study by Pastor, Núria, Khalilian, Elizabeth, Caballeria, Elsa, Morrison, Danielle, Sanchez Luque, Unai, Matrai, Silvia, Gual, Antoni, López-Pelayo, Hugo

“…BACKGROUNDMonitoring mental health outcomes has traditionally been based on heuristic decisions, often based on scarce, subjective evidence, making the…”
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PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells by Szalinski, Christina M, Guerriero, Christopher J, Ruiz, Wily G, Docter, Brianne E, Rbaibi, Youssef, Pastor-Soler, Núria M, Apodaca, Gerard, Puthenveedu, Manojkumar A, Weisz, Ora A

“…Localized synthesis of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] at clathrin coated pits (CCPs) is crucial for the recruitment of adaptors and…”
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Regulation of Epithelial Na+ Transport by Soluble Adenylyl Cyclase in Kidney Collecting Duct Cells by Hallows, Kenneth R., Wang, Huamin, Edinger, Robert S., Butterworth, Michael B., Oyster, Nicholas M., Li, Hui, Buck, Jochen, Levin, Lonny R., Johnson, John P., Pastor-Soler, Núria M.

“…Alkalosis impairs the natriuretic response to diuretics, but the underlying mechanisms are unclear. The soluble adenylyl cyclase (sAC) is a chemosensor that…”
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Luminal flow modulates H+-ATPase activity in the cortical collecting duct (CCD) by Liu, Wen, Pastor-Soler, Núria M, Schreck, Carlos, Zavilowitz, Beth, Kleyman, Thomas R, Satlin, Lisa M

“…Epithelial Na(+) channel (ENaC)-mediated Na(+) absorption and BK channel-mediated K(+) secretion in the cortical collecting duct (CCD) are modulated by flow,…”
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AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1 by Fraser, Scott A, Choy, Suet-Wan, Pastor-Soler, Núria M, Li, Hui, Davies, Matthew R P, Cook, Natasha, Katerelos, Marina, Mount, Peter F, Gleich, Kurt, McRae, Jennifer L, Dwyer, Karen M, van Denderen, Bryce J W, Hallows, Kenneth R, Kemp, Bruce E, Power, David A

“…Salt reabsorption is the major energy-requiring process in the kidney, and AMP-activated protein kinase (AMPK) is an important regulator of cellular…”
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Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model by Pastor-Soler, Núria M, Li, Hui, Pham, Jessica, Rivera, Daniel, Ho, Pei-Yin, Mancino, Valeria, Saitta, Biagio, Hallows, Kenneth R

“…Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in the polycystin 1 ( ) or polycystin 2 genes, presents with progressive development…”
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