Search Results - "Pastewska, Monika"

Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches by Pastewska, Monika, Żołnowska, Beata, Kovačević, Strahinja, Kapica, Hanna, Gromelski, Maciej, Stoliński, Filip, Sławiński, Jarosław, Sawicki, Wiesław, Ciura, Krzesimir

“…Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work,…”
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Improved wet granulation techniques by Pastewska, Monika, Sawicki, Wiesław

“…Wet granulation is one of the most frequently used processes in the pharmaceutical industry to manufacture solid dosage forms. Wet granulation is helpful in…”
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Can Immobilized Artificial Membrane Chromatography Support the Characterization of Antimicrobial Peptide Origin Derivatives? by Ciura, Krzesimir, Ptaszyńska, Natalia, Kapica, Hanna, Pastewska, Monika, Łęgowska, Anna, Rolka, Krzysztof, Kamysz, Wojciech, Sawicki, Wiesław, Greber, Katarzyna E.

“…The emergence and spread of multiple drug-resistant bacteria strains caused the development of new antibiotics to be one of the most important challenges of…”
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Prediction of the chromatographic hydrophobicity index with immobilized artificial membrane chromatography using simple molecular descriptors and artificial neural networks by Ciura, Krzesimir, Kovačević, Strahinja, Pastewska, Monika, Kapica, Hanna, Kornela, Martyna, Sawicki, Wiesław

“…•QSRR modeling of immobilized artificial membrane chromatography.•Insights into the molecular mechanism of retention in IAM-HPLC.•Compression of MLR and ANN to…”
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Chemometric analysis of bio-inspired micellar electrokinetic chromatographic systems – modelling of retention mechanism and prediction of biological properties using bile salts surfactants by Ciura, Krzesimir, Pastewska, Monika, Ulenberg, Szymon, Kapica, Hanna, Kawczak, Piotr, Bączek, Tomasz

“…•QRAR model for estimating the predicted human intestinal absorption (HIA) was proposed.•Comparison of sodium cholate and sodium deoxycholate pseudostationary…”
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Use of biomimetic chromatography and in vitro assay to develop predictive GA-MLR model for use in drug-property prediction among anti-depressant drug candidates by Ulenberg, Szymon, Ciura, Krzesimir, Georgiev, Paweł, Pastewska, Monika, Ślifirski, Grzegorz, Król, Marek, Herold, Franciszek, Bączek, Tomasz

“…[Display omitted] •Drug properties significant for further development were estimated.•Chosen properties were metabolic stability, lipophilicity, membrane…”
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Modification of gradient HPLC method for determination of small molecules' affinity to human serum albumin under column safety conditions: Robustness and chemometrics study by Woziński, Mateusz, Greber, Katarzyna Ewa, Pastewska, Monika, Kolasiński, Piotr, Hewelt-Belka, Weronika, Żołnowska, Beata, Sławiński, Jarosław, Szulczyk, Daniel, Sawicki, Wiesław, Ciura, Krzesimir

“…In the early stages of drug discovery, beyond the biological activity screening, determining the physicochemical properties that affect the distribution of…”
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Multivariate assessment of anticancer oleanane triterpenoids lipophilicity by Pastewska, Monika, Bednarczyk-Cwynar, Barbara, Kovačević, Strahinja, Buławska, Natalia, Ulenberg, Szymon, Georgiev, Paweł, Kapica, Hanna, Kawczak, Piotr, Bączek, Tomasz, Sawicki, Wiesław, Ciura, Krzesimir

“…•Assessment of anticancer oleanane triterpenoids lipophilicity.•QSRR modeling of OA derivatives retention on reversed-phase liquid chromatography.•Comparison…”
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