Search Results - "Pasternack, R."
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1
A skin reaction with rust‐like discolouration to mRNA COVID‐19 vaccine
Published in Journal of the European Academy of Dermatology and Venereology (01-11-2021)Get full text
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Effect of zinc cations on the kinetics of supramolecular assembly and the chirality of porphyrin J-aggregates
Published in Chemical science (Cambridge) (01-02-2017)“…Dilute aqueous solutions of anionic -4-sulfonatophenyl-porphyrin (TPPS) extract zinc(ii) ions from glass or quartz surfaces at room temperature and efficiently…”
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Resonance Light Scattering: A New Technique for Studying Chromophore Aggregation
Published in Science (American Association for the Advancement of Science) (18-08-1995)“…Light scattering experiments are usually performed at wavelengths away from absorption bands, but for species that aggregate, enhancements in light scattering…”
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Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
Published in Clinical cancer research (01-11-1997)“…Expression of high levels of fatty acid synthase (FAS), an important enzyme in fatty acid synthesis, has been identified in a wide variety of human carcinomas…”
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Phosphorylated Retinoblastoma Protein Complexes with pp32 and Inhibits pp32-mediated Apoptosis
Published in The Journal of biological chemistry (22-04-2005)“…The retinoblastoma gene product (Rb) is a tumor suppressor that affects apoptosis paradoxically. Most sporadic cancers inactivate Rb by preferentially…”
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Qualitative Study Exploring Implementation of a Point-of-Care Competency-Based Lumbar Puncture Program Across Institutions
Published in Academic pediatrics (01-09-2016)“…Abstract Objective To explore the factors that facilitated or hindered successful implementation of a multi-centered infant lumbar puncture (LP)…”
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Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia
Published in The American journal of pathology (01-01-1997)“…Expression of the primary enzyme catalyzing the synthesis of fatty acids, ie, fatty acid synthase (FAS), and ex vivo fatty acid synthetic activity were…”
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Fatty Acid Synthesis: A Potential Selective Target for Antineoplastic Therapy
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-1994)“…OA-519 is a prognostic molecule found in tumor cells from breast cancer patients with markedly worsened prognosis. We purified OA-519 from human breast…”
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Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells
Published in Cancer research (Chicago, Ill.) (15-06-1996)“…One of the key limiting factors in the treatment of advanced stage human epithelial malignancies is the lack of new, selective molecular targets for…”
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Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer
Published in Cancer research (Chicago, Ill.) (15-03-1996)“…One of the key limiting factors in the treatment of advanced stage human epithelial malignancies is the lack of selective molecular targets for antineoplastic…”
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Case-Based Workshop for Teaching Child Abuse Prevention to Resident Physicians
Published in MedEdPORTAL (03-03-2017)“…Child abuse is a ubiquitous problem with personal, interpersonal, and social consequences. Risk factors are well established, and preventive strategies have…”
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Fatty acid synthase expression in endometrial carcinoma: Correlation with cell proliferation and hormone receptors
Published in Cancer (01-08-1998)“…Fatty acid synthase (FAS), a biosynthetic enzyme, normally functions in the liver to convert dietary carbohydrate to fat, but it is minimally expressed in most…”
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A pp32–retinoblastoma protein complex modulates androgen receptor-mediated transcription and associates with components of the splicing machinery
Published in Biochemical and biophysical research communications (26-08-2005)“…We have previously shown pp32 and the retinoblastoma protein interact. pp32 and the retinoblastoma protein are nuclear receptor transcriptional coregulators:…”
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Fatty acid synthase (FAS) : a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells
Published in Cancer research (Chicago, Ill.) (15-02-1996)“…Many human cancers express elevated levels of fatty acid synthase (FAS), with correspondingly increased fatty acid synthesis and abnormal fatty acid…”
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Tumor suppression and potentiation by manipulation of pp32 expression
Published in Oncogene (19-04-2001)“…Alternative use of genes of the closely-related pp32 family is a common occurrence in human prostate cancer. pp32r1 and pp32r2, the oncogenic members of the…”
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Modulation of oncogenic potential by alternative gene use in human prostate cancer
Published in Nature medicine (01-03-1999)“…Only a small percentage of primary prostate cancers have genetic changes. In contrast, nearly 90% of clinically significant human prostate cancers seems to…”
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Porphyrin assemblies on DNA as studied by a resonance light-scattering technique
Published in Journal of the American Chemical Society (30-06-1993)“…Under appropriate conditions of concentration and ionic strength, trans-bis(N-methylpyridinium-4-yl) -diphenylporphine and its copper(II) derivative produce…”
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Identification of Sequences Required for Inhibition of Oncogene-mediated Transformation by pp32
Published in The Journal of biological chemistry (16-07-1999)“…Oncogenic potential in prostate cancer is modulated in part by alternative use of genes of the pp32 family. This family includes the tumor suppressor pp32 ,…”
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Tuning Porphyrin/DNA Supramolecular Assemblies by Competitive Binding
Published in Journal of the American Chemical Society (16-06-2004)“…Addition of an intercalating but nonaggregating porphyrin, AuT4, to a preformed adduct between DNA and a strongly aggregating porphyrin, t-H2Pagg, permits…”
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