Search Results - "Passos, Giselle F"

Taxane‐induced neurotoxicity: Pathophysiology and therapeutic perspectives by Costa, Robson, Passos, Giselle F., Quintão, Nara L.M., Fernandes, Elizabeth S., Maia, João Raphael L.C.B., Campos, Maria Martha, Calixto, João B.

“…Taxane‐derived drugs are antineoplastic agents used for the treatment of highly common malignancies. Paclitaxel and docetaxel are the most commonly used…”
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Spinal blockage of CXCL1 and its receptor CXCR2 inhibits paclitaxel-induced peripheral neuropathy in mice by Manjavachi, Marianne N., Passos, Giselle F., Trevisan, Gabriela, Araújo, Suzana B., Pontes, Jaqueline P., Fernandes, Elizabeth S., Costa, Robson, Calixto, Joao B.

“…Painful peripheral neuropathy is the most dose-limiting side effect of paclitaxel (PTX), a widely used anti-cancer drug to treat solid tumours. The…”
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The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice by Dias, Fabiana C., Alves, Vinícius S., Matias, Daiane O., Figueiredo, Claudia P., Miranda, Ana Luisa P., Passos, Giselle F., Costa, Robson

“…Painful diabetic neuropathy (PDN) is a serious symptom that compromises quality of life and remains without effective pharmacological treatment. The transient…”
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Anti-inflammatory effects of compounds alpha-humulene and (−)- trans-caryophyllene isolated from the essential oil of Cordia verbenacea by Fernandes, Elizabeth S., Passos, Giselle F., Medeiros, Rodrigo, da Cunha, Fernanda M., Ferreira, Juliano, Campos, Maria M., Pianowski, Luiz F., Calixto, João B.

“…This study evaluated the anti-inflammatory properties of two sesquiterpenes isolated from Cordia verbenacea's essential oil, α-humulene and (−)-…”
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The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice by Passos, Giselle F., Medeiros, Rodrigo, Marcon, Rodrigo, Nascimento, Andrey F.Z., Calixto, João B., Pianowski, Luiz F.

“…Inflammation underlies the development and progression of a number of skin disorders including psoriasis, atopic dermatitis and cancer. Therefore, novel…”
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Consequences of gestational diabetes to the brain and behavior of the offspring by Sousa, Ricardo A L DE, Torres, Yasmin S, Figueiredo, Claudia P, Passos, Giselle F, Clarke, Julia R

“…Gestational diabetes mellitus (GD) is a form of insulin resistance triggered during the second/third trimesters of pregnancy in previously normoglycemic women…”
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Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea by Passos, Giselle F., Fernandes, Elizabeth S., da Cunha, Fernanda M., Ferreira, Juliano, Pianowski, Luiz F., Campos, Maria M., Calixto, João B.

“…The anti-inflammatory and anti-allergic effects of the essential oil of Cordia verbenacea (Boraginaceae) and some of its active compounds were evaluated…”
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Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy by Vasilevko, Vitaly, Passos, Giselle F., Quiring, Daniel, Head, Elizabeth, Kim, Richard C., Fisher, Mark, Cribbs, David H.

“…Age‐related cerebrovascular dysfunction contributes to ischemic stroke, intracerebral hemorrhages (ICHs), microbleeds, cerebral amyloid angiopathy (CAA), and…”
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Aspirin-Triggered Lipoxin A4 Stimulates Alternative Activation of Microglia and Reduces Alzheimer Disease–Like Pathology in Mice by Medeiros, Rodrigo, Kitazawa, Masashi, Passos, Giselle F, Baglietto-Vargas, David, Cheng, David, Cribbs, David H, LaFerla, Frank M

“…Microglia play an essential role in innate immunity, homeostasis, and neurotropic support in the central nervous system. In Alzheimer disease (AD), these cells…”
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Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice by Segat, Gabriela C., Manjavachi, Mariane N., Matias, Daiane O., Passos, Giselle F., Freitas, Cristina Setim, Costa, Robson, Calixto, João B.

“…Painful peripheral neuropathy is a common side effect of paclitaxel (PTX). The use of analgesics is an important component for management of PTX-induced…”
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Kinin B1 Receptor Up-Regulation after Lipopolysaccharide Administration: Role of Proinflammatory Cytokines and Neutrophil Influx by Passos, Giselle F, Fernandes, Elizabeth S, Campos, Maria M, Araujo, Jose G. V. C, Pesquero, Jorge L, Souza, Gloria E. P, Avellar, Maria C. W, Teixeira, Mauro M, Calixto, Joao B

“…Several studies have now clearly established the ability of LPS to induce bradykinin B(1) receptor up-regulation in vivo and the functional relevance of this…”
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Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles by Figueiredo, Claudia P, Ferreira, Natalia C, Passos, Giselle F, Costa, Robson da, Neves, Fernanda S, Machado, Clarice S C, Mascarello, Alessandra, Chiaradia-Delatorre, Louise D, Neuenfeldt, Patrícia D, Nunes, Ricardo J, Cordeiro, Yraima

“…An altered form of the cellular prion protein, the PrPScor PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform…”
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Abatacept inhibits Th17 differentiation and mitigates α-synuclein-induced dopaminergic dysfunction in mice by Clarke, Julia R, Bacelar, Thiago Sa, Fernandes, Gabriel Gripp, Silva, Raquel Costa da, Antonio, Leticia S, Queiroz, Mariana, de Souza, Renata V, Valadão, Leticia F, Ribeiro, Gabriel S, De Lima, Emanuelle V, Colodeti, Lilian C, Mangeth, Luana C, Wiecikowski, Adalgisa, da Silva, Talita N, Paula-Neto, Heitor A, da Costa, Robson, Cordeiro, Yraima, Passos, Giselle F, Figueiredo, Claudia P

“…Parkinson's disease (PD) is a multifaceted disease characterized by degeneration of nigrostriatal dopaminergic neurons, which results in motor and non-motor…”
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Mitotherapy prevents peripheral neuropathy induced by oxaliplatin in mice by Maia, João R.L. C.B., Machado, Loreena K.A., Fernandes, Gabriel G., Vitorino, Louise C., Antônio, Letícia S., Araújo, Suzana Maria B., Colodeti, Lilian C., Fontes-Dantas, Fabrícia L., Zeidler, Julianna D., Saraiva, Georgia N., Da Poian, Andrea T., Figueiredo, Claudia P., Passos, Giselle F., da Costa, Robson

“…Oxaliplatin (OXA) is an antineoplastic agent used for the treatment of cisplatin-resistant tumours, presenting lower incidence of nephrotoxicity and…”
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Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer’s Disease by Petrushina, Irina, Davtyan, Hayk, Hovakimyan, Armine, Davtyan, Arpine, Passos, Giselle F., Cribbs, David H., Ghochikyan, Anahit, Agadjanyan, Michael G.

“…Previously, we reported that Alzheimer’s disease (AD) epitope vaccines (EVs) composed of N-terminal β-amyloid (Aβ42) B cell epitope fused with universal…”
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Experimental hypertension increases spontaneous intracerebral hemorrhages in a mouse model of cerebral amyloidosis by Passos, Giselle F, Kilday, Kelley, Gillen, Daniel L, Cribbs, David H, Vasilevko, Vitaly

“…Hypertension and cerebral amyloid angiopathy (CAA) are major risk factors for intracerebral hemorrhage (ICH); however the mechanisms of interplay between the…”
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Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice by Simão da Silva, Kathryn A.B., Paszcuk, Ana F., Passos, Giselle F., Silva, Eduardo S., Bento, Allisson Freire, Meotti, Flavia C., Calixto, João B.

“…The pentacyclic triterpene α,β-amyrin binds to CB1 and CB2 receptors and reduces inflammation and hyperalgesia in 2 models of persistent pain in mice. In this…”
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Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein by Medeiros, Rodrigo, Prediger, Rui D S, Passos, Giselle F, Pandolfo, Pablo, Duarte, Filipe S, Franco, Jeferson L, Dafre, Alcir L, Di Giunta, Gabriella, Figueiredo, Cláudia P, Takahashi, Reinaldo N, Campos, Maria M, Calixto, João B

“…Increased brain deposition of amyloid beta protein (Abeta) and cognitive deficits are classical signals of Alzheimer's disease (AD) that have been highly…”
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Therapeutic Modulation of Cerebral Microhemorrhage in a Mouse Model of Cerebral Amyloid Angiopathy by FISHER, Mark, VASILEVKO, Vitaly, PASSOS, Giselle F, VENTURA, Christopher, QUIRING, Daniel, CRIBBS, David H

“…The aging brain demonstrates frequent MRI and pathological evidence of cerebral microbleeds, which are often associated with cerebral amyloid angiopathy. To…”
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The Bradykinin B1 Receptor Regulates Aβ Deposition and Neuroinflammation in Tg-SwDI Mice by Passos, Giselle F, Medeiros, Rodrigo, Cheng, David, Vasilevko, Vitaly, LaFerla, Frank M, Cribbs, David H

“…The deposition of amyloid-β peptides (Aβ) in the cerebral vasculature, a condition known as cerebral amyloid angiopathy, is increasingly recognized as an…”
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