Search Results - "Passmore, Linda"
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MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma
Published in PloS one (03-09-2010)“…MicroRNAs (miRNAs) are a family of small, non-coding RNA species functioning as negative regulators of multiple target genes including tumour suppressor genes…”
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The effect of different radiological models on diagnostic accuracy and lung cancer screening performance
Published in Thorax (01-12-2017)“…High false-positive (FP) scan rates associated with low-dose computed tomography (LDCT) lung cancer screening result in unnecessary follow-up tests and…”
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Brief Tailored Smoking Cessation Counseling in a Lung Cancer Screening Population is Feasible: A Pilot Randomized Controlled Trial
Published in Nicotine & tobacco research (01-07-2016)“…Maximizing smoking abstinence in lung cancer screening participants is important to reduce individual risk of disease and improve screening cost-effectiveness;…”
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Cost of screening for lung cancer in Australia
Published in Internal medicine journal (01-11-2019)“…Background Lung cancer screening can reduce lung cancer mortality. Australian cost estimates are important to inform policy but remain uncertain. Aim To…”
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Gene Expression Signature Predicts Recurrence in Lung Adenocarcinoma
Published in Clinical cancer research (15-05-2007)“…Purpose: Improving outcomes for early-stage lung cancer is a major research focus at present because a significant proportion of stage I patients develop…”
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Pleural fluid cell-free DNA integrity index to identify cytologically negative malignant pleural effusions including mesotheliomas
Published in BMC cancer (25-09-2012)“…The diagnosis of malignant pleural effusions (MPE) is often clinically challenging, especially if the cytology is negative for malignancy. DNA integrity index…”
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ADAM28: A potential oncogene involved in asbestos-related lung adenocarcinomas
Published in Genes chromosomes & cancer (01-08-2010)“…Asbestos‐related lung cancer accounts for 4–12% of all lung cancers worldwide. Since putative mechanisms of carcinogenesis differ between asbestos and tobacco…”
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Genetic influences on right ventricular systolic pressure (RVSP) in chronic obstructive pulmonary disease (COPD)
Published in BMC pulmonary medicine (13-06-2012)“…Pulmonary hypertension (PH) is a complication of chronic obstructive pulmonary disease (COPD). This study examined genetic variations in mediators of vascular…”
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Expression profiling defines a recurrence signature in lung squamous cell carcinoma
Published in Carcinogenesis (New York) (01-03-2007)“…Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is ∼10–15% and despite curative intent surgery, treatment failure is…”
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Phenotypes and karyotypes of human malignant mesothelioma cell lines
Published in PloS one (14-03-2013)“…Malignant mesothelioma is an aggressive tumour of serosal surfaces most commonly pleura. Characterised cell lines represent a valuable tool to study the…”
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Lung asbestos content in lungs resected for primary lung cancer
Published in Journal of thoracic oncology (01-06-2008)“…The majority of Australia's burden of lung cancer occurs in current or former tobacco smokers. To determine the possible contribution of asbestos exposure in…”
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USPSTF2013 versus PLCOm2012 lung cancer screening eligibility criteria (International Lung Screening Trial): interim analysis of a prospective cohort study
Published in The lancet oncology (01-01-2022)“…Lung cancer is a major health problem. CT lung screening can reduce lung cancer mortality through early diagnosis by at least 20%. Screening high-risk…”
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Validation of the Eighth Edition TNM Lung Cancer Staging System
Published in Journal of thoracic oncology (01-04-2020)“…We performed a validation study at our institution, the International Union Against Cancer (Union for International Cancer Control latest version of TNM…”
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Active screening for lung cancer increases smoking abstinence in Australia
Published in Asia-Pacific journal of clinical oncology (01-06-2023)“…Background Smoking cessation is an important screening component, but the evidence base to inform implementation is lacking. We report longitudinal smoking…”
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Protocol and Rationale for the International Lung Screening Trial
Published in Annals of the American Thoracic Society (01-04-2020)“…: The NLST (National Lung Screening Trial) reported a 20% reduction in lung cancer mortality with low-dose computed tomography screening; however, important…”
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Lung cancer screening feasibility in Australia
Published in The European respiratory journal (01-06-2015)“…The National Lung Screening Trial (NLST) reported a 20% relative reduction in lung cancer-specific mortality using low-dose computed tomography (LDCT)…”
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Screen-detected subsolid pulmonary nodules: long-term follow-up and application of the PanCan lung cancer risk prediction model
Published in British journal of radiology (01-01-2016)“…To report the long-term follow-up of subsolid nodules (SSNs) detected in participants of a prospective low-dose CT lung cancer screening cohort, and to…”
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Abstract 24: Intratumoral genomic heterogeneity of primary pulmonary adenocarcinoma in never smokers
Published in Clinical cancer research (01-01-2016)“…Abstract Aim: Intratumoral genomic heterogeneity challenges personalized lung cancer care, especially where it relies upon small diagnostic samples. To explore…”
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Low tumour cell content in a lung tumour bank: implications for molecular characterisation
Published in Pathology (01-10-2017)“…Lung cancer encompasses multiple malignant epithelial tumour types, each with specific targetable, potentially actionable mutations, such that precision…”
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