Search Results - "Passmore, Anthony Peter"

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease by Graham, Stewart F, Chevallier, Olivier P, Elliott, Christopher T, Hölscher, Christian, Johnston, Janet, McGuinness, Bernadette, Kehoe, Patrick G, Passmore, Anthony Peter, Green, Brian D

“…This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients…”
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Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study) by Femminella, Grazia Daniela, Frangou, Eleni, Love, Sharon B, Busza, Gail, Holmes, Clive, Ritchie, Craig, Lawrence, Robert, McFarlane, Brady, Tadros, George, Ridha, Basil H, Bannister, Carol, Walker, Zuzana, Archer, Hilary, Coulthard, Elizabeth, Underwood, Ben R, Prasanna, Aparna, Koranteng, Paul, Karim, Salman, Junaid, Kehinde, McGuinness, Bernadette, Nilforooshan, Ramin, Macharouthu, Ajay, Donaldson, Andrew, Thacker, Simon, Russell, Gregor, Malik, Naghma, Mate, Vandana, Knight, Lucy, Kshemendran, Sajeev, Harrison, John, Hölscher, Christian, Brooks, David J, Passmore, Anthony Peter, Ballard, Clive, Edison, Paul

“…Liraglutide is a glucagon-like peptide-1 (GLP-1) analogue currently approved for type 2 diabetes and obesity. Preclinical evidence in transgenic models of…”
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Metabolomics and computational analysis of the role of monoamine oxidase activity in delirium and SARS-COV-2 infection by Cuperlovic-Culf, Miroslava, Cunningham, Emma L., Teimoorinia, Hossen, Surendra, Anuradha, Pan, Xiaobei, Bennett, Steffany A. L., Jung, Mijin, McGuiness, Bernadette, Passmore, Anthony Peter, Beverland, David, Green, Brian D.

“…Delirium is an acute change in attention and cognition occurring in ~ 65% of severe SARS-CoV-2 cases. It is also common following surgery and an indicator of…”
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Inflammation and anti-inflammatory strategies for Alzheimer's disease--a mini-review by McNaull, Benjamin Brian Alexander, Todd, Stephen, McGuinness, Bernadette, Passmore, Anthony Peter

“…Until recently, the central nervous system (CNS) has been thought to be an immune privileged organ. However, it is now understood that neuroinflammation is…”
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Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? by Femminella, Grazia Daniela, Livingston, Nicholas R, Raza, Sanara, van der Doef, Thalia, Frangou, Eleni, Love, Sharon, Busza, Gail, Calsolaro, Valeria, Carver, Stefan, Holmes, Clive, Ritchie, Craig W, Lawrence, Robert M, McFarlane, Brady, Tadros, George, Ridha, Basil H, Bannister, Carol, Walker, Zuzana, Archer, Hilary, Coulthard, Elizabeth, Underwood, Ben, Prasanna, Aparna, Koranteng, Paul, Karim, Salman, Junaid, Kehinde, McGuinness, Bernadette, Passmore, Anthony Peter, Nilforooshan, Ramin, Macharouthu, Ajayverma, Donaldson, Andrew, Thacker, Simon, Russell, Gregor, Malik, Naghma, Mate, Vandana, Knight, Lucy, Kshemendran, Sajeev, Tan, Tricia, Holscher, Christian, Harrison, John, Brooks, David J, Ballard, Clive, Edison, Paul

“…Type 2 diabetes is a risk factor for Alzheimer's disease (AD), and AD brain shows impaired insulin signalling. The role of peripheral insulin resistance on AD…”
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A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort by Skrobot, Olivia Anna, McKnight, Amy Jayne, Passmore, Peter Anthony, Seripa, Davide, Mecocci, Patrizia, Panza, Francesco, Kalaria, Rajesh, Wilcock, Gordon, Munafò, Marcus, Erkinjuntti, Timo, Karhunen, Pekka, Pessi, Tanja, Martiskainen, Mika, Love, Seth, Kehoe, Patrick Gavin

“…Vascular cognitive impairment (VCI), including its severe form, vascular dementia (VaD), is the second most common form of dementia. The genetic etiology of…”
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Developing a person-centered stated preference survey for dementia with Lewy bodies: value of a personal and public involvement process by Donnelly, Paula Sinead, Sweeney, Aoife, Wilson, Emily, Passmore, Anthony Peter, McCorry, Noleen K, Boeri, Marco, Kane, Joseph P M

“…The development of high-quality stated preference (SP) surveys requires a rigorous design process involving engagement with representatives from the target…”
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Correction to: Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer’s disease: study protocol for a randomised controlled trial (ELAD study) by Femminella, Grazia Daniela, Frangou, Eleni, Love, Sharon B, Busza, Gail, Holmes, Clive, Ritchie, Craig, Lawrence, Robert, McFarlane, Brady, Tadros, George, Ridha, Basil H, Bannister, Carol, Walker, Zuzana, Archer, Hilary, Coulthard, Elizabeth, Underwood, Ben R, Prasanna, Aparna, Koranteng, Paul, Karim, Salman, Junaid, Kehinde, McGuinness, Bernadette, Nilforooshan, Ramin, Macharouthu, Ajay, Donaldson, Andrew, Thacker, Simon, Russell, Gregor, Malik, Naghma, Mate, Vandana, Knight, Lucy, Kshemendran, Sajeev, Harrison, John, Hölscher, Christian, Brooks, David J, Passmore, Anthony Peter, Ballard, Clive, Edison, Paul

“…An amendment to this paper has been published and can be accessed via the original article…”
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Pisa syndrome due to donepezil: pharmacokinetic interactions to blame? by Pollock, David, Cunningham, Emma, McGuinness, Bernadette, Passmore, Anthony Peter

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Elective Surgery in People with Dementia in Northern Ireland by O'Hara, Leeanne, Zafeiridi, Evi, Passmore, Anthony Peter, Cunningham, Emma L, McGuinness, Bernadette

“…Background Elective care is defined as care that is planned in advance for those that require a procedure or treatment for an existing condition. Elective…”
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The influence of antipsychotics and antidepressants on people with dementia in Northern Ireland: A retrospective analysis by McMichael, Alan J, Zafeiridi, Evi, Passmore, Anthony Peter, McGuinness, Bernadette

“…Background Dementia is a term used to describe a broad group of conditions that affect the brain and causes a progressive cognitive decline in the ability to…”
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The influence of antipsychotics and antidepressants on people with dementia in Northern Ireland: A retrospective analysis: Epidemiology / Prevalence, incidence, and outcomes of MCI and dementia by McMichael, Alan J, Zafeiridi, Evi, Passmore, Anthony Peter, McGuinness, Bernadette

“…Abstract Background Dementia is a term used to describe a broad group of conditions that affect the brain and causes a progressive cognitive decline in the…”
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Lower serum carotenoid levels are associated with incident cognitive decline independent of traditional risk factors in a prospective study of older men from Northern Ireland by McKay, Gareth J, Linden, Gerry, Patterson, Christopher, Passmore, Anthony Peter, McEvoy, Claire T, Woodside, Jayne V, Holmes, Clive, McGuinness, Bernadette

“…Background Nutritional influences, and antioxidant status in particular, have been implicated in the aetiology of cognitive decline. This study investigated…”
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Pisa syndrome due to donepezil: pharmacokinetic interactions to blame? by Pollock, David, Cunningham, Emma, McGuinness, Bernadette, Passmore, Anthony Peter

“…We report a case of Pisa syndrome (PS) due to the acetylcholinesterase inhibitor donepezil which may have been precipitated by pharmacokinetic interactions…”
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Periodontitis and future cognitive decline by McGuinness, Bernadette, Passmore, Anthony Peter, Holmes, Clive, Teeling, Jessica, Linden, Gerry, Farsi, Dominic, McEvoy, Claire T, McKay, Gareth J, Abadelkareem, Rana, Patterson, Christopher, McAlinden, Michael

“…Background Periodontitis (gum disease) is a is a chronic inflammatory disorder. Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Aggregatibacter…”
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Hand grip strength, anthropometrics and cognitive decline by McGuinness, Bernadette, Passmore, Anthony Peter, Holmes, Clive, Patterson, Christopher, Linden, Gerry, McEvoy, Claire T, McAlinden, Michael, McKay, Gareth J, Farsi, Dominic, Teeling, Jessica

“…Background Hand grip strength is a well validated measure of physical strength, while anthropometric measures such as weight, waist, hip and mid upper arm…”
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Delirium Following Elective Arthroplasty Predicts Mild Cognitive Impairment (MCI) and Dementia Eight Years Later However This Is Not Independent of Pre‐Operative Neurodegenerative Biomarkers And Cognition by Sweeney, Aoife, Passmore, Anthony Peter, Beverland, David, McGuinness, Bernadette, McAuley, Daniel F, O'Brien, Seamus, Heslegrave, Amanda, Schott, Jonathan M, Zetterberg, Henrik, Veleva, Elena, Laban, Rhiannon, Cunningham, Emma L

“…Background In 2012‐2014, an observational cohort study of postoperative delirium (POD) in an elective arthroplasty population recruited 315 individuals aged…”
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Cerebrospinal Fluid Markers of Neurodegeneration Associated with Postoperative Delirium in an Older Elective Arthroplasty Population by Sweeney, Aoife, Passmore, Anthony Peter, Beverland, David, McGuinness, Bernadette, McAuley, Daniel F, Mawhinney, Tim, Schott, Jonathan M, Heslegrave, Amanda, Zetterberg, Henrik, Cunningham, Emma L

“…Background Postoperative delirium (POD) is associated with subsequent cognitive decline. It is not yet clear to what extent that is because delirium indicates…”
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Preoperative Cerebrospinal Fluid and Plasma Markers of Inflammation and Neurodegeneration Predict Mortality Eight Years Later in an Observational Cohort Study of Postoperative delirium in an Older Elective Arthroplasty Populatio by Sweeney, Aoife, Passmore, Anthony Peter, Beverland, David, McGuinness, Bernadette, McAuley, Daniel F, Mawhinney, Tim, O'Brien, Seamus, Schott, Jonathan M, Heslegrave, Amanda, Zetterberg, Henrik, Cunningham, Emma L

“…Background Between 2012‐2014, an observational cohort study of postoperative delirium (POD) in an elective arthroplasty population recruited 315 individuals…”
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Plasma Markers of Neurodegeneration Associated with Postoperative Delirium in an Older Elective Arthroplasty Population by Sweeney, Aoife, Passmore, Anthony Peter, Beverland, David, McGuinness, Bernadette, McAuley, Daniel F, Mawhinney, Tim, O'Brien, Seamus, Schott, Jonathan M, Heslegrave, Amanda, Zetterberg, Henrik, Cunningham, Emma L

“…Background Postoperative delirium (POD) is associated with subsequent cognitive decline. It is not yet clear to what extent that is because delirium indicates…”
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