Search Results - "Passarelli, A. Lorena"

Tissue Barriers to Arbovirus Infection in Mosquitoes by Franz, Alexander W E, Kantor, Asher M, Passarelli, A Lorena, Clem, Rollie J

“…Arthropod-borne viruses (arboviruses) circulate in nature between arthropod vectors and vertebrate hosts. Arboviruses often cause devastating diseases in…”
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Baculoviruses: sophisticated pathogens of insects by Clem, Rollie J, Passarelli, A Lorena

“…  [...]even in the AcMNPV genome, roughly half of the genes have no assigned function, meaning that there are probably many more interesting baculovirus…”
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Barriers to success: How baculoviruses establish efficient systemic infections by Passarelli, A. Lorena

“…Abstract The mechanisms used by baculoviruses to exit the midgut and cause systemic infection of their insect hosts have been debated for decades. After being…”
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Heritable CRISPR/Cas9-mediated genome editing in the yellow fever mosquito, Aedes aegypti by Dong, Shengzhang, Lin, Jingyi, Held, Nicole L, Clem, Rollie J, Passarelli, A Lorena, Franz, Alexander W E

“…In vivo targeted gene disruption is a powerful tool to study gene function. Thus far, two tools for genome editing in Aedes aegypti have been applied,…”
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Autographa californica Multiple Nucleopolyhedrovirus Ac92 (ORF92, P33) Is Required for Budded Virus Production and Multiply Enveloped Occlusion-Derived Virus Formation by WENBI WU, PASSARELLI, A. Lorena

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Transcriptional Reprogramming of Autographa Californica Multiple Nucleopolyhedrovirus Chitinase and Cathepsin Genes Enhances Virulence by Hodgson, Jeffrey J, Passarelli, A Lorena, Krell, Peter J

“…The baculoviral chitinase (CHIA) and cathepsin (V-CATH) enzymes promote terminal insect host liquefaction, which aids viral progeny dissemination. Recombinant…”
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The Autographa californica M Nucleopolyhedrovirus ac79 Gene Encodes an Early Gene Product with Structural Similarities to UvrC and Intron-Encoded Endonucleases That Is Required for Efficient Budded Virus Production by WENBI WU, PASSARELLI, A. Lorena

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Effects of Manipulating Fibroblast Growth Factor Expression on Sindbis Virus Replication In Vitro and in Aedes aegypti Mosquitoes by Wu, Wenbi, Simmons, Cody A, Moffitt, Jessica, Clem, Rollie J, Passarelli, A Lorena

“…Fibroblast growth factors (FGFs) are conserved among vertebrate and invertebrate animals and function in cell proliferation, cell differentiation, tissue…”
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Viral fibroblast growth factor, matrix metalloproteases, and caspases are associated with enhancing systemic infection by baculoviruses by Means, John C, Passarelli, A. Lorena

“…Most arthropod-borne and invertebrate viruses are orally ingested and commence infection in cells of the invertebrate intestine. Infection of secondary sites…”
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Baculovirus Infection Induces a DNA Damage Response That Is Required for Efficient Viral Replication by Huang, Ning, Wu, Wenbi, Yang, Kai, Passarelli, A Lorena, Rohrmann, George F, Clem, Rollie J

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The Trichoplusia ni single nucleopolyhedrovirus tn79 gene encodes a functional sulfhydryl oxidase enzyme that is able to support the replication of Autographa californica multiple nucleopolyhedrovirus lacking the sulfhydryl oxidase ac92 gene by Clem, Stian A, Wu, Wenbi, Lorena Passarelli, A

“…Abstract The Autographa californica multiple nucleopolyhedrovirus ac92 is a conserved baculovirus gene with homology to flavin adenine dinucleotide-linked…”
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Intrahaemocoelic infection of Trichoplusia ni with the baculovirus Autographa californica M nucleopolyhedrovirus does not induce tracheal cell basal lamina remodelling by Means, John C, Passarelli, A Lorena

“…Infection of the lepidopteran insect Trichoplusia ni with the baculovirus Autographa californica M nucleopolyhedrovirus (AcMNPV) by the oral route stimulates…”
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Virion-associated viral fibroblast growth factor stimulates cell motility by Lehiy, Christopher Jon, Martinez, Olga, Passarelli, A. Lorena

“…Abstract The Autographa californica M nucleopolyhedrovirus (Ac M NPV) viral fibroblast growth factor (vFGF) has functional parallels to cellular FGFs. Deletion…”
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Novel Genetic and Molecular Tools for the Investigation and Control of Dengue Virus Transmission by Mosquitoes by Franz, Alexander W. E., Clem, Rollie J., Passarelli, A. Lorena

“…Aedes aegypti is the principal vector of dengue virus (DENV) throughout the tropical world. This anthropophilic mosquito species needs to be persistently…”
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Mature viral cathepsin is required for release of viral occlusion bodies from Autographa californica multiple nucleopolyhedrovirus-infected cells by Hodgson, Jeffrey J., Krell, Peter J., Passarelli, A. Lorena

“…Baculovirus-infected larvae release progeny viral occlusion bodies (OBs) to enable cyclical virus transmission to new hosts. The alphabaculovirus chitinase and…”
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Reaching the melting point: Degradative enzymes and protease inhibitors involved in baculovirus infection and dissemination by Ishimwe, Egide, Hodgson, Jeffrey J, Clem, Rollie J, Passarelli, A. Lorena

“…Abstract Baculovirus infection of a host insect involves several steps, beginning with initiation of virus infection in the midgut, followed by dissemination…”
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Inhibition of dicer activity in lepidopteran and dipteran cells by baculovirus-mediated expression of Flock House virus B2 by Hodgson, Jeffrey J., Wenger, Luke W., Clem, Rollie J., Passarelli, A. Lorena

“…Prior studies have suggested that insect DNA viruses are negatively affected by dicer-2-mediated RNA interference (RNAi). To examine this further, we utilized…”
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Analysis of a baculovirus lacking a functional viral fibroblast growth factor homolog by Detvisitsakun, Chanitchote, Hutfless, Erica L., Berretta, Marcelo F., Passarelli, A. Lorena

“…Baculoviruses encode fibroblast growth factor (vfgf) homologs whose function during virus infection is unknown. We constructed a recombinant bacmid of…”
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Infection pattern and transmission potential of chikungunya virus in two New World laboratory-adapted Aedes aegypti strains by Dong, Shengzhang, Kantor, Asher M., Lin, Jingyi, Passarelli, A. Lorena, Clem, Rollie J., Franz, Alexander W. E.

“…Chikungunya virus (CHIKV) is an emerging mosquito-borne virus belonging to the Togaviridae , which is transmitted to humans by Aedes aegypti and Ae. albopictus…”
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Analysis and functional annotation of expressed sequence tags from the fall armyworm Spodoptera frugiperda by Deng, Youping, Dong, Yinghua, Thodima, Venkata, Clem, Rollie J, Passarelli, A Lorena

“…Little is known about the genome sequences of lepidopteran insects, although this group of insects has been studied extensively in the fields of endocrinology,…”
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