Search Results - "Passananti, C."
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Hippocampal dynamics of synaptic NF-kappa B during inhibitory avoidance long-term memory consolidation in mice
Published in Neuroscience (16-04-2015)“…Highlights • NF-kappa B is present at the synapses. • Synaptic NF-kappa B is activated during memory consolidation. • NF-kappa B may also have a local role at…”
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2
Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53
Published in Cell death & disease (01-05-2015)“…The tumor suppressor p53 is mainly involved in the transcriptional regulation of a large number of growth-arrest- and apoptosis-related genes. However, a clear…”
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3
HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation
Published in Cell death & disease (11-09-2014)“…Che-1/AATF is an RNA polymerase II-binding protein that is involved in the regulation of gene transcription, which undergoes stabilization and accumulation in…”
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Che-1 activates XIAP expression in response to DNA damage
Published in Cell death and differentiation (01-03-2008)“…X-linked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis proteins family that selectively binds and inhibits caspase-3, -7 and…”
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The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription
Published in Gene therapy (01-06-2000)“…Up-regulation of utrophin gene expression is recognized as a plausible therapeutic approach in the treatment of Duchenne muscular dystrophy (DMD). We have…”
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The artificial zinc finger protein ‘Blues’ binds the enhancer of the fibroblast growth factor 4 and represses transcription
Published in FEBS letters (27-02-2004)“…The design of novel genes encoding artificial transcription factors represents a powerful tool in biotechnology and medicine. We have engineered a new zinc…”
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Structure of an inverted duplication formed as a first step in a gene amplification event: implications for a model of gene amplification
Published in The EMBO journal (01-06-1987)“…Inverted duplications have been observed to be a common feature of gene amplification in mammalian cells and appear to be generated as a primary event in the…”
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Mutations in the VP1 coding region of polyomavirus determine differentiating stage specificity
Published in Journal of Virology (01-12-1992)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mouse Genes Coding for "Zinc-Finger"-Containing Proteins: Characterization and Expression in Differentiated Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1989)“…By using the zinc-finger region of human cHF.10 cDNA as a probe at low-stringency hybridization conditions, several individual phages from a mouse skeletal…”
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10
Constitutive synthesis of polyoma antisense RNA renders cells immune to virus infection
Published in Virology (New York, N.Y.) (01-08-1992)“…Mouse fibroblasts were stably transfected with expression plasmids in which sequences of the early region of polyomavirus were inserted both in sense and…”
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A Polyomavirus Enhancer Mutant Confers Ubiquitous High Transcriptional Efficiency to the SV40 Late Promoter
Published in Biochemical and biophysical research communications (06-02-1995)“…To identify expression plasmids with high efficiency of transcription and with a broad tissue and cell range, we have constructed a recombinant vector…”
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Protein recognition sites in polyomavirus enhancer: formation of a novel site for NF‐1 factor in an enhancer mutant and characterization of a site in the enhancer D domain
Published in The EMBO journal (01-03-1990)“…Polyomavirus mutants selected for modified host range exhibit DNA sequence alterations in the regulatory region, which consist mainly of duplications and/or…”
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13
Che-1/AATF, a multivalent adaptor connecting transcriptional regulation, checkpoint control, and apoptosis
Published in Biochemistry and cell biology (01-08-2007)“…Che-1/AATF (Che-1) was originally characterized as an interacting protein for RNA polymerase II. In addition to transcriptional regulation, the evidence…”
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14
Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb
Published in Cancer cell (01-11-2002)“…DNA tumor virus oncoproteins bind and inactivate Rb by interfering with the Rb/HDAC1 interaction. Che-1 is a recently identified human Rb binding protein that…”
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Selection of mouse neuroblastoma cell‐specific polyoma virus mutants with stage differentiative advantages of replication
Published in The EMBO journal (01-12-1985)“…Two mouse neuroblastoma cell lines were analyzed for their permissivity for polyoma virus growth. One (N18) is fully permissive for polyoma replication, the…”
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Che-1 Arrests Human Colon Carcinoma Cell Proliferation by Displacing HDAC1 from the p21 Promoter
Published in The Journal of biological chemistry (19-09-2003)Get full text
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Che-1 enhances cyclin-dependent kinase 5 expression and interacts with the active kinase-complex
Published in Neuroreport (26-03-2008)“…Che-1 is a nuclear protein involved in the regulation of gene transcription and cell proliferation. It has also been shown to localize to the cytoplasm of…”
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Genomic structure and transcriptional regulation of Che-1, a novel partner of Rb
Published in Gene (04-12-2003)“…We recently identified and cloned a novel human gene, Che-1, whose product interacts with both RNA polymerase II and the retinoblastoma gene product (Rb)…”
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Functional interaction of the subunit 3 of RNA polymerase II (RPB3) with transcription factor-4 (ATF4)
Published in FEBS letters (17-07-2003)“…RPB3 is a core subunit of RNA polymerase II (pol II) that, together with the RPB11 subunit, forms the heterodimer considered as a functional counterpart of the…”
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Identification of a novel partner of RNA polymerase II subunit 11, Che‐1, which interacts with and affects the growth suppression function of Rb
Published in The FASEB journal (01-05-2000)“…hRPB11 is a core subunit of RNA polymerase II (pol II) specifically down‐regulated on doxorubicin (dox) treatment. Levels of this protein profoundly affect…”
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