Search Results - "Pasqualucci, L"

Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity by Marsilio, S, Khiabanian, H, Fabbri, G, Vergani, S, Scuoppo, C, Montserrat, E, Shpall, E J, Hadigol, M, Marin, P, Rai, K R, Rabadan, R, Devereux, S, Pasqualucci, L, Chiorazzi, N

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SUPER‐ENHANCER HYPERMUTATION IN DLBCL: ROLE OF ALTERATIONS IN THE GLUCOCORTICOID RECEPTOR PATHWAY by Bal, E., Corinaldesi, C., Holmes, A. B, Pasqualucci, L., Basso, K., Dalla‐Favera, R.

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The NPM1 wild-type OCI-AML2 and the NPM1-mutated OCI-AML3 cell lines carry DNMT3A mutations by Tiacci, E, Spanhol-Rosseto, A, Martelli, M P, Pasqualucci, L, Quentmeier, H, Grossmann, V, Drexler, H G, Falini, B

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Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma by Xia, Y, Xu-Monette, Z Y, Tzankov, A, Li, X, Manyam, G C, Murty, V, Bhagat, G, Zhang, S, Pasqualucci, L, Visco, C, Dybkaer, K, Chiu, A, Orazi, A, Zu, Y, Richards, K L, Hsi, E D, Choi, W W L, van Krieken, J H, Huh, J, Ponzoni, M, Ferreri, A J M, Møller, M B, Parsons, B M, Winter, J N, Piris, M A, Westin, J, Fowler, N, Miranda, R N, Ok, C Y, Li, Y, Li, J, Medeiros, L J, Young, K H

“…PRDM1 /BLIMP-1, a master regulator of plasma-cell differentiation, is frequently inactivated in activated B-cell-like (ABC) diffuse large B-cell lymphoma…”
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GENETICALLY DISTINCT PATHOGENESIS OF EPSTEIN‐BARR VIRUS (EBV)‐POSITIVE VERSUS EBV‐NEGATIVE CLASSICAL HODGKIN (CHL) LYMPHOMA by Gomez, K., Schiavoni, G., Nam, Y., Reynier, J., Khamnei, C., Aitken, M., van Noesel, C., Falini, B., Pasqualucci, L., Rabadan, R., Tiacci, E.

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BTG2 SUPER‐ENHANCER MUTATIONS DISRUPT TFAP4 BINDING AND DYSREGULATE BTG2 EXPRESSION IN DIFFUSE LARGE B‐CELL LYMPHOMA by Bal, E., De Simone, P., Holmes, A. B., Hilton, L., Basso, K., Soni, R. K., Morin, R. D., Dalla‐Favera, R., Pasqualucci, L.

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CREBBP MEDIATED ACETYLATION OF KMT2D IN NORMAL AND TRANSFORMED GC B CELLS by Vlasevska, S., Garcia‐Ibanez, L., Duval, R., Holmes, A.B., Jahan, R., Basso, K., Dalla‐Favera, R., Pasqualucci, L.

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Protein expression analysis of chromosome 12 candidate genes in chronic lymphocytic leukemia (CLL) by WINKLER, D, SCHNEIDER, C, KRÖBER, A, PASQUALUCCI, L, LICHTER, P, DÖHNER, H, STILGENBAUER, S

“…The pathogenic role of trisomy 12 in chronic lymphocytic leukemia (CLL) remains unresolved, but recently an upregulated RNA expression level has been observed…”
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NPM1-mutated acute myeloid leukaemia occurring in JAK2-V617F+ primary myelofibrosis: de-novo origin? by Pasqualucci, L, Li, S, Meloni, G, Schnittger, S, Gattenlohner, S, Liso, A, Di Ianni, M, Martelli, M P, Pescarmona, E, Foa, R, Haferlach, T, Skoda, R C, Falini, B

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Aberrant somatic hypermutation in primary mediastinal large B-cell lymphoma by ROSSI, D, CERRI, M, PILERI, S. A, PASQUALUCCI, L, GAIDANO, G, CAPELLO, D, DEAMBROGI, C, BERRA, E, FRANCESCHETTI, S, ALABISO, O, GLOGHINI, A, PAULLI, M, CARBONE, A

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New approaches to lymphoma diagnosis by Harris, N L, Stein, H, Coupland, S E, Hummel, M, Favera, R D, Pasqualucci, L, Chan, W C

“…Recent years have brought an explosion of new diagnostic tools to the pathology of lymphomas, which have permitted more precise disease definition and…”
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Bcl-6 protein expression in normal and neoplastic lymphoid tissues by FALINI, B, FIZZOTTI, M, PILERI, S, LISO, A, PASQUALUCCI, L, FLENGHI, L

“…The human bcl-6 gene, which is rearranged in about 30% of diffuse large B-cell lymphomas (DLCL-B), encodes for a Kruppel-type zinc finger protein of 706 amino…”
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Molecular pathogenesis of B cell malignancy: the role of BCL-6 by Dalla-Favera, R, Migliazza, A, Chang, C C, Niu, H, Pasqualucci, L, Butler, M, Shen, Q, Cattoretti, G

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Monoclonal antibodies PG-B6a and PG-B6p recognize, respectively, a highly conserved and a formol-resistant epitope on the human BCL-6 protein amino-terminal region by Flenghi, L, Bigerna, B, Fizzotti, M, Venturi, S, Pasqualucci, L, Pileri, S, Ye, BH, Gambacorta, M, Pacini, R, Baroni, CD, Pescarmona, E, Anagnostopoulos, I, Stein, H, Asdrubali, G, Martelli, MF, Pelicci, PG, Dalla-Favera, R, Falini, B

“…The human BCL-6 gene, which is rearranged in approximately 30% of diffuse large B cell lymphomas, encodes a 706-amino-acid nuclear protein of the Kruppel-type…”
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17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 - 17 June, 2023 by Bal, E, Corinaldesi, C, Holmes, A B, Pasqualucci, L, Basso, K, Dalla-Favera, R

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Heterogeneous nuclear expression of the promyelocytic leukemia (PML) protein in normal and neoplastic human tissues by Gambacorta, M, Flenghi, L, Fagioli, M, Pileri, S, Leoncini, L, Bigerna, B, Pacini, R, Tanci, LN, Pasqualucci, L, Ascani, S, Mencarelli, A, Liso, A, Pelicci, PG, Falini, B

“…The RING-finger promyelocytic leukemia (PML) protein is the product of the PML gene that fuses with the retinoic acid receptor-alpha gene in the t(15; 17)…”
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Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas by Georgiou, Konstantinos, Chen, Longyun, Berglund, Mattias, Ren, Weicheng, de Miranda, Noel F.C.C., Lisboa, Susana, Fangazio, Marco, Zhu, Shida, Hou, Yong, Wu, Kui, Fang, Wenfeng, Wang, Xianhuo, Meng, Bin, Zhang, Li, Zeng, Yixin, Bhagat, Govind, Nordenskjöld, Magnus, Sundström, Christer, Enblad, Gunilla, Dalla-Favera, Riccardo, Zhang, Huilai, Teixeira, Manuel R., Pasqualucci, Laura, Peng, Roujun, Pan-Hammarström, Qiang

“…Diffuse large B-cell lymphoma (DLBCL) is one of the most common and aggressive types of B-cell lymphoma. Deregulation of proto-oncogene expression after a…”
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Mediastinal large B-cell lymphoma: clinical and immunohistological findings in 18 patients treated with different third-generation regimens by Falini, B, Venturi, S, Martélli, M, Santucci, A, Pileri, S, Pescarmona, E, Giovannini, M, Mazza, P, Martelli, M F, Pasqualucci, L

“…We report on the immunophenotype, clinical findings and response to aggressive chemotherapy of 18 patients with mediastinal large B-cell lymphoma (MLCL). Cases…”
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Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma by Fangazio, Marco, Ladewig, Erik, Gomez, Karen, Garcia-Ibanez, Laura, Kumar, Rahul, Teruya-Feldstein, Julie, Rossi, Davide, Filip, Ioan, Pan-Hammarström, Qiang, Inghirami, Giorgio, Boldorini, Renzo, Ott, German, Staiger, Annette M., Chapuy, Björn, Gaidano, Gianluca, Bhagat, Govind, Basso, Katia, Rabadan, Raul, Pasqualucci, Laura, Dalla-Favera, Riccardo

“…Fifty percent of diffuse large B cell lymphoma (DLBCL) cases lack cell-surface expression of the class I major histocompatibility complex (MHC-I), thus…”
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A Signaling Pathway Mediating Downregulation of BCL6 in Germinal Center B Cells Is Blocked by BCL6 Gene Alterations in B Cell Lymphoma by Saito, Masumichi, Gao, Jie, Basso, Katia, Kitagawa, Yukiko, Smith, Paula M., Bhagat, Govind, Pernis, Alessandra, Pasqualucci, Laura, Dalla-Favera, Riccardo

“…The BCL6 proto-oncogene encodes a transcriptional repressor necessary for the development of germinal centers (GCs) and directly implicated in lymphomagenesis…”
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