Search Results - "Pashov, Anastas D"

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies by Hadzhieva, Maya, Pashov, Anastas D., Kaveri, Srinivas, Lacroix-Desmazes, Sébastien, Mouquet, Hugo, Dimitrov, Jordan D.

“…The density and distribution pattern of epitopes at the surface of pathogens have a profound impact on immune responses. Although multiple lines of evidence…”
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Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects by Hutchins, Laura F, Makhoul, Issam, Emanuel, Peter D, Pennisi, Angela, Siegel, Eric R, Jousheghany, Fariba, Guo, Xueyan, Pashov, Anastas D, Monzavi-Karbassi, Behjatolah, Kieber-Emmons, Thomas

“…Tumor-associated carbohydrate antigens (TACAs) support cell survival that could be interrupted by anti-TACA antibodies. Among TACAs that mediate cell survival…”
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Potential SARS-CoV-2 Preimmune IgM Epitopes by Shivarov, Velizar, Petrov, Peter K, Pashov, Anastas D

“…While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of…”
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The Patterns of Coevolution in Clade B HIV Envelope's N-Glycosylation Sites by Garimalla, Swetha, Kieber-Emmons, Thomas, Pashov, Anastas D

“…The co-evolution of the potential N-glycosylation sites of HIV Clade B gp120 was mapped onto the coevolution network of the protein structure using mean field…”
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Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity by Lecerf, Maxime, Scheel, Tobias, Pashov, Anastas D., Jarossay, Annaelle, Ohayon, Delphine, Planchais, Cyril, Mesnage, Stephane, Berek, Claudia, Kaveri, Srinivas V., Lacroix-Desmazes, Sébastien, Dimitrov, Jordan D.

“…The healthy immune repertoire contains a fraction of antibodies that bind to various biologically relevant cofactors, including heme. Interaction of heme with…”
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Antibody polyspecificity: what does it matter? by Dimitrov, Jordan D, Pashov, Anastas D, Vassilev, Tchavdar L

“…Polyspecificity (polyreactivity) is currently considered an intrinsic property of a subset of antibodies, primarily of naturally occurring autoantibodies…”
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Multiple Antigenic Mimotopes of HIV Carbohydrate Antigens: Relating Structure and Antigenicity by Pashov, Anastas D, Plaxco, Jason, Kaveri, Srinivas V, Monzavi-Karbassi, Behjatolah, Harn, Donald, Kieber-Emmons, Thomas

“…Carbohydrate mimetic peptides are designable, and they can carry T-cell epitopes and circumvent tolerance. A mimic-based human immunodeficiency virus (HIV)…”
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Glycan mediated immune responses to tumor cells by Pashov, Anastas D., Monzavi-Karbassi, Behjatolah, Kieber-Emmons, Thomas

“…Preclinical animal studies convincingly demonstrate that tumor immunity to self-antigens can be actively induced and can translate into effective anti-tumor…”
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Multiple Antigenic Mimotopes of HIV Carbohydrate Antigens by Pashov, Anastas D., Plaxco, Jason, Kaveri, Srinivas V., Monzavi-Karbassi, Behjatolah, Harn, Donald, Kieber-Emmons, Thomas

“…Carbohydrate mimetic peptides are designable, and they can carry T-cell epitopes and circumvent tolerance. A mimic-based human immunodeficiency virus (HIV)…”
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Serum IgM, IgG and IgA block by F(ab′)2-dependent mechanism the binding of natural IgG autoantibodies from therapeutic immunoglobulin preparations to self-antigens by Djoumerska, Iglika K., Tchorbanov, Andrey I., Donkova-Petrini, Vladimira D., Pashov, Anastas D., Vassilev, Tchavdar L.

“…:  Natural polyreactive IgG autoantibodies are present in the plasma of healthy individuals and as a result in pooled therapeutic intravenous immunoglobulin…”
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Serum IgM, IgG and IgA block by F(ab')-dependent mechanism the binding of natural IgG autoantibodies from therapeutic immunoglobulin preparations to self-antigens by Djoumerska, Iglika K, Tchorbanov, Andrey I, Donkova-Petrini, Vladimira D, Pashov, Anastas D, Vassilev, Tchavdar L

“…Natural polyreactive IgG autoantibodies are present in the plasma of healthy individuals and as a result in pooled therapeutic intravenous immunoglobulin…”
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