Search Results - "Pasha, Mazhar"

Redox changes and cellular senescence in Alzheimer's disease by Yu, Nicole, Pasha, Mazhar, Chua, John Jia En

“…The redox process and cellular senescence are involved in a range of essential physiological functions. However, they are also implicated in pathological…”
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Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases by Gorin, Yves, Eid, Assaad, Eid, Ali H., Pasha, Mazhar, Munusamy, Shankar

“…Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against…”
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The effect of tauroursodeoxycholic Acid (TUDCA) treatment on placental endoplasmic reticulum (ER) stress in a rat model of advanced maternal age by Pasha, Mazhar, Kirschenman, Raven, Wooldridge, Amy, Spaans, Floor, Cooke, Christy-Lynn M, Davidge, Sandra T

“…Advanced maternal age (≥35 years) is associated with an increased risk of pregnancy complications such as fetal growth restriction and preeclampsia. We…”
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Advanced Maternal Age Impairs Uterine Artery Adaptations to Pregnancy in Rats by Wooldridge, Amy L, Pasha, Mazhar, Chitrakar, Palehswan, Kirschenman, Raven, Quon, Anita, Spaans, Floor, Sáez, Tamara, Cooke, Christy-Lynn M, Davidge, Sandra T

“…Advanced maternal age (≥35 years) is associated with pregnancy complications. Aging impairs vascular reactivity and increases vascular stiffness. We…”
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Microparticles as Potential Mediators of High Glucose-Induced Renal Cell Injury by Ravindran, Sreenithya, Pasha, Mazhar, Agouni, Abdelali, Munusamy, Shankar

“…Diabetic nephropathy (DN) is the most common cause of chronic kidney disease worldwide. Activation of signaling pathways such as the mammalian target of…”
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Altered Vascular Adaptations to Pregnancy in a Rat Model of Advanced Maternal Age by Pasha, Mazhar, Wooldridge, Amy L, Kirschenman, Raven, Spaans, Floor, Davidge, Sandra T, Cooke, Christy-Lynn M

“…Advanced maternal age (≥35 years old) increases the risk of pregnancy complications such as preeclampsia and fetal growth restriction. We previously…”
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The Effect of Tauroursodeoxycholic Acid (TUDCA) Treatment on Pregnancy Outcomes and Vascular Function in a Rat Model of Advanced Maternal Age by Pasha, Mazhar, Kirschenman, Raven, Wooldridge, Amy, Spaans, Floor, Cooke, Christy-Lynn M, Davidge, Sandra T

“…Advanced maternal age (≥35 years) increases the risk of vascular complications in pregnancy that can result in fetal growth restriction and preeclampsia…”
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Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines by Pasha, Mazhar, Sivaraman, Siveen K, Frantz, Ronald, Agouni, Abdelali, Munusamy, Shankar

“…Clear cell renal cell carcinoma (ccRCC) is the most common and lethal form of urological cancer diagnosed globally. Mutations of the von Hippel-Lindau…”
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Endoplasmic Reticulum (ER) Stress-Generated Extracellular Vesicles (Microparticles) Self-Perpetuate ER Stress and Mediate Endothelial Cell Dysfunction Independently of Cell Survival by Osman, Aisha, El-Gamal, Heba, Pasha, Mazhar, Zeidan, Asad, Korashy, Hesham M, Abdelsalam, Shahenda S, Hasan, Maram, Benameur, Tarek, Agouni, Abdelali

“…Circulating extracellular vesicles (EVs) are recognized as biomarkers and effectors of endothelial dysfunction, the initiating step of cardiovascular…”
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The Long-Term Effects of Prenatal Hypoxia on Coronary Artery Function of the Male and Female Offspring by Hula, Nataliia, Liu, Ricky, Spaans, Floor, Pasha, Mazhar, Quon, Anita, Kirschenman, Raven, Cooke, Christy-Lynn M, Davidge, Sandra T

“…Prenatal hypoxia predisposes the offspring to the development of cardiovascular (CV) dysfunction in adult life. Using a rat model, we assessed the effect of…”
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Chicken muscle hydrolysate reduces blood pressure in spontaneously hypertensive rats, upregulates ACE2, and ameliorates vascular inflammation, fibrosis, and oxidative stress by Fan, Hongbing, Liao, Wang, Spaans, Floor, Pasha, Mazhar, Davidge, Sandra T., Wu, Jianping

“…Spent hens are egg‐laying chicken reaching the end of their egg‐laying cycle and are seen as a by‐product to the egg industry. A spent hen muscle protein…”
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ANTI‐NEOPLASTIC EFFECTS OF METFORMIN AGAINST RENAL CLEAR CELL CARCINOMA by Munusamy, Shankar, Pasha, Mazhar, Agouni, Abdelali

“…Background and Objectives Renal clear cell carcinoma (RCCC) is the most common and lethal form of urological cancer diagnosed globally. Mutation of Von‐Hippel…”
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The effect of tauroursodeoxycholic Acid by Pasha, Mazhar, Kirschenman, Raven, Wooldridge, Amy, Spaans, Floor, Cooke, Christy-Lynn M, Davidge, Sandra T

“…Advanced maternal age ([greater than or equal to]35 years) is associated with an increased risk of pregnancy complications such as fetal growth restriction and…”
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The effect of tauroursodeoxycholic Acid stress in a rat model of advanced maternal age by Pasha, Mazhar, Kirschenman, Raven, Wooldridge, Amy, Spaans, Floor, Cooke, Christy-Lynn M, Davidge, Sandra T

“…Advanced maternal age ([greater than or equal to]35 years) is associated with an increased risk of pregnancy complications such as fetal growth restriction and…”
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Endoplasmic Reticulum (ER) stress‐generated microparticles self‐perpetuate ER stress and mediate endothelial cell dysfunction independently of cell survival by Agouni, Abdelali, Osman, Aisha, El Gamal, Heba, Pasha, Mazhar

“…Abstract only Microparticles (MPs) are nanosized membrane‐shed vesicles released from activated cells. MPs can induce endothelial dysfunction, the first step…”
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Differential Selectivity of the Renal Clear Cell Carcinoma Cell Lines to the Antineoplastic Effects of Metformin by Munusamy, Shankar, Pasha, Mazhar, Frantz, Ronald, Agouni, Abdelali

“…Background Renal clear cell carcinoma (RCCC) accounts for 3–5% of all cancers among US adults. Mutations in the Von‐Hippel Lindau (VHL) tumor suppresser gene…”
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Protein Tyrosine Phosphatase (PTP) 1B Inhibition Improves Endoplasmic Reticulum Stress‐Induced Apoptosis in Endothelial Cells by Agouni, Abdelali, Pasha, Mazhar, Abdelsalam, Shahenda, El Gamal, Heba

“…Background Endoplasmic Reticulum (ER) stress response, which is activated in obesity and diabetes, contributes to the development of endothelial dysfunction in…”
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The Effect of Tauroursodeoxycholic Acid (TUDCA) Treatment on Pregnancy Outcomes and Uterine Artery Function in a Rat Model of Advanced Maternal Age by Pasha, Mazhar, Kirschenman, Raven, Wooldridge, Amy, Spaans, Floor, Cooke, Christy‐ Lynn, Davidge, Sandra T.

“…Introduction Advanced maternal age (AMA; ≥35 years) increases the risk of pregnancy complications and adverse pregnancy outcomes such as fetal growth…”
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Advanced maternal age alters cardiac functional and structural adaptations to pregnancy in rats by Wooldridge, Amy L, Kirschenman, Raven, Spaans, Floor, Pasha, Mazhar, Davidge, Sandra T, Cooke, Christy-Lynn M

“…A significant number of pregnancies occur at advanced maternal age (>35 yr), which is a risk factor for pregnancy complications. Healthy pregnancies require…”
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Prenatal Hypoxia is Associated with Coronary Artery Endothelial Dysfunction in Male and Female Offspring by Hula, Nataliia, Pasha, Mazhar, Quon, Anita, Kirschenman, Raven, Cooke, Christy‐Lynn M., Spaans, Floor, Davidge, Sandra T.

“…Introduction Fetal hypoxia is a common consequence of complicated pregnancies and is linked to the development of cardiovascular (CV) dysfunction in the…”
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