Search Results - "Pasdar, Alireza"

PD‐1/PD‐L1 pathway: Basic biology and role in cancer immunotherapy by Salmaninejad, Arash, Valilou, Saeed Farajzadeh, Shabgah, Arezoo Gowhari, Aslani, Saeed, Alimardani, Malihe, Pasdar, Alireza, Sahebkar, Amirhossein

“…Over the course of past few years, cancer immunotherapy has been accompanied with promising results. However, preliminary investigations with respect to…”
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AutoMap is a high performance homozygosity mapping tool using next-generation sequencing data by Quinodoz, Mathieu, Peter, Virginie G, Bedoni, Nicola, Royer Bertrand, Béryl, Cisarova, Katarina, Salmaninejad, Arash, Sepahi, Neda, Rodrigues, Raquel, Piran, Mehran, Mojarrad, Majid, Pasdar, Alireza, Ghanbari Asad, Ali, Fonseca Vieira Álvares Sousa Ferrand Almeida, Ana Berta, Santos, Maria Luisa, Superti-Furga, Andrea, Rivolta, Carlo

“…© The Author(s) 2021. Open AccessThis article is licensed under a Creative CommonsAttribution 4.0 International License, which permits use, sharing,adaptation,…”
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GATA3 somatic mutations are associated with clinicopathological features and expression profile in TCGA breast cancer patients by Afzaljavan, Fahimeh, Sadr, Ayeh Sadat, Savas, Sevtap, Pasdar, Alireza

“…The effect of somatic mutations and the gene expression profiles on the prognosis is well documented in cancer research. This study was conducted to evaluate…”
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Clinical significance of circulating tumor cell related markers in patients with epithelial ovarian cancer before and after adjuvant chemotherapy by Yousefi, Meysam, Rajaie, Sara, Keyvani, Vahideh, Bolandi, Somayeh, Hasanzadeh, Malihe, Pasdar, Alireza

“…Circulating tumor cells (CTCs) have recently been considered as new prognostic and diagnostic markers for various human cancers; however, their significance in…”
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Current insights into the metastasis of epithelial ovarian cancer - hopes and hurdles by Yousefi, Meysam, Dehghani, Sadegh, Nosrati, Rahim, Ghanei, Mahmoud, Salmaninejad, Arash, Rajaie, Sara, Hasanzadeh, Malihe, Pasdar, Alireza

“…Background Ovarian cancer is the most lethal gynecologic cancer and the fifth leading cause of cancer-related mortality in women worldwide. Despite various…”
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The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment by Gholamin, Sharareh, Pasdar, Alireza, Khorrami, Mohammad Sadegh, Mirzaei, Hamed, Mirzaei, Hamid Reza, Salehi, Rasoul, Ferns, Gordon A, Ghayour-Mobarhan, Majid, Avan, Amir

“…MicroRNAs (miRNAs) are a class of small regulatory RNAs that control several cellular processes that may contribute to development of cardiovascular disease…”
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Whole exome sequencing in 17 consanguineous Iranian pedigrees expands the mutational spectrum of inherited retinal dystrophies by Rehman, Atta Ur, Sepahi, Neda, Bedoni, Nicola, Ravesh, Zeinab, Salmaninejad, Arash, Cancellieri, Francesca, Peter, Virginie G., Quinodoz, Mathieu, Mojarrad, Majid, Pasdar, Alireza, Asad, Ali Ghanbari, Ghalamkari, Saman, Piran, Mehran, Piran, Mehrdad, Superti-Furga, Andrea, Rivolta, Carlo

“…Inherited retinal dystrophies (IRDs) constitute one of the most heterogeneous groups of Mendelian human disorders. Using autozygome-guided next-generation…”
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A novel causative functional mutation in GATA6 gene is responsible for familial dilated cardiomyopathy as supported by in silico functional analysis by Khazamipour, Afrouz, Gholampour-Faroji, Nazanin, Zeraati, Tina, Vakilian, Farveh, Haddad-Mashadrizeh, Aliakbar, Ghayour Mobarhan, Majid, Pasdar, Alireza

“…Dilated cardiomyopathy (DCM), one of the most common types of cardiomyopathies has a heterogeneous nature and can be seen in Mendelian forms. Next Generation…”
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Familial combined hyperlipidemia: An overview of the underlying molecular mechanisms and therapeutic strategies by Taghizadeh, Eskandar, Esfehani, Reza Jafarzadeh, Sahebkar, Amirhossein, Parizadeh, Seyed Mostafa, Rostami, Daryoush, Mirinezhad, Mohammadreza, Poursheikhani, Arash, Mobarhan, Majid Ghayour, Pasdar, Alireza

“…Among different types of dyslipidemia, familial combined hyperlipidemia (FCHL) is the most common genetic disorder, which is characterized by at least two…”
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Whole exome sequencing and homozygosity mapping reveals genetic defects in consanguineous Iranian families with inherited retinal dystrophies by Salmaninejad, Arash, Bedoni, Nicola, Ravesh, Zeinab, Quinodoz, Mathieu, Shoeibi, Nasser, Mojarrad, Majid, Pasdar, Alireza, Rivolta, Carlo

“…Inherited retinal dystrophies (IRDs), displaying pronounced genetic and clinical heterogeneity, comprise of a broad range of diseases characterized by…”
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ESR1 gene variants, haplotypes and diplotypes may influence the risk of breast cancer and mammographic density by Khorshid Shamshiri, Asma, Afzaljavan, Fahimeh, Alidoust, Maryam, Taherian, Vahideh, Vakili, Fatemeh, Moezzi, Atefeh, Homaei Shandiz, Fatemeh, Farrokh, Donya, Pasdar, Alireza

“…Breast cancer as the most common cancer worldwide is influenced by genetic and physiological factors. Based on some evidence indicating the role of estrogen…”
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Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran by Afzaljavan, Fahimeh, Vahednia, Elham, Barati Bagherabad, Matineh, Vakili, Fatemeh, Moezzi, Atefeh, Hosseini, Azar, Homaei Shandiz, Fatemeh, Kooshyar, Mohammad Mahdi, Nassiri, Mohammadreza, Pasdar, Alireza

“…Multiple genome-wide and candidate-gene association studies have been conducted to search for common risk variants of breast cancer. Recent large meta-analyses…”
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Micronutrients intake and genetic variants associated with premature ovarian insufficiency; MASHAD cohort study by Mirinezhad, Mohammad Reza, Aghsizadeh, Maliheh, Ghazizadeh, Hamideh, Ghoflchi, Sahar, Bidary, Mohammad Zamiri, Naghipour, Alireza, Ferns, Gordon A, Hamzehloei, Tayebeh, Pasdar, Alireza, Ghayour-Mobarhan, Majid

“…premature ovarian insufficiency (POI) is defined as the menopause before 40 years of age, and its prevalence is reported to be two-fold higher in Iranian women…”
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Association between serum cell adhesion molecules with hs-CRP, uric acid and VEGF genetic polymorphisms in subjects with metabolic syndrome by Ghazizadeh, Hamideh, Rezaei, Majid, Avan, Amir, Fazilati, Mohammad, Pasdar, Alireza, Tavallaie, Shima, Kazemi, Elham, Seyedi, Seyed Mohammad Reza, Ferns, Gordon A., Azimi-Nezhad, Mohsen, Ghayour-Mobarhan, Majid

“…Metabolic syndrome (MetS) is associated with a pro-inflammatory state and endothelial dysfunction that places subjects with MetS at a higher risk of…”
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Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk by Alidoust, Maryam, Hamzehzadeh, Leila, Khorshid Shamshiri, Asma, Afzaljavan, Fahimeh, Kerachian, Mohammad Amin, Fanipakdel, Azar, Aledavood, Seyed Amir, Allahyari, Abolghasem, Bari, Alireza, Moosanen Mozaffari, Hooman, Goshayeshi, Ladan, Pasdar, Alireza

“…Colorectal cancer (CRC) is one of the common cancers with a high mortality rate worldwide. In Iran, there has been a trend of increased incidence of colorectal…”
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Potential Role of Zinc Finger 365 rs10822013 and rs10995190 in Mammographic Density, Sporadic Breast Cancer Risk, and Prognosis by Ghadamgahi, Seyed Reza, Hosseinzadeh, Leila, Ardalan Khales, Sahar, Nassiri, Mohammadreza, Alidoust, Maryam, Etemadrezaei, Shirin, Khorshid Shamshiri, Asma, Homaei Shandiz, Fatemeh, Pasdar, Alireza, Afzaljavan, Fahimeh

“…Despite suggesting many genetic risk markers as the outcome of Genome-wide association studies (GWAS) for breast cancer, replicating the results in different…”
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The 9p21 Locus and its Potential Role in Atherosclerosis Susceptibility; Molecular Mechanisms and Clinical Implications by Tajbakhsh, Amir, Khorrami, Mohammad Sadegh, Hassanian, Seyed Mahdi, Aghasizade, Malihe, Pasdar, Alireza, Maftouh, Mina, Tabatabai, Ehsan, Parizadeh, Seyed Mohammad Reza, Fazeli, Mostafa, Ferns, Gordon A, Ghayour-Mobarhan, Majid, Avan, Amir

“…Cardiovascular disease (CVD) is the leading cause of global mortality. Although extensive efforts have been made to identify valid biomarkers for CVD risk,…”
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Association between serum cytokine concentrations and the presence of hypertriglyceridemia by Mirhafez, Seyed Reza, Tajfard, Mohammad, Avan, Amir, Pasdar, Alireza, Nedaeinia, Reza, Aghasizade, Malihe, Davari, Hafezeh, Manian, Mostafa, Mahdizadeh, Adeleh, Meshkat, Zahra, Movahedi, Ali, Amini, Nahid Ghaed, Eskandari, Nahid, Salehi, Rasoul, Ferns, Gordon A., Ghayour-Mobarhan, Majid

“…Hypertriglyceridemia is an established risk factor for coronary-heart-disease. Inflammatory cytokines are known to be important mediators of atherogenesis;…”
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Association of PICK1 and BDNF variations with increased risk of methamphetamine dependence among Iranian population: a case-control study by Tajbakhsh, Amir, Alimardani, Maliheh, Asghari, Mahla, Abedini, Soheila, Saghafi Khadem, Sohrab, Nesaei Bajestani, Abolfazl, Alipoor, Forough, Alidoust, Maryam, Savardashtaki, Amir, Hashemian, Peyman, Pasdar, Alireza

“…Genetic factors play an important role in susceptibility to methamphetamine dependency. In this line, protein that interact with C-kinase-1 (PICK1) and…”
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An imbalance in serum concentrations of inflammatory and anti-inflammatory cytokines in hypertension by Mirhafez, Seyed Reza, Mohebati, Mohsen, Feiz Disfani, Mahboobeh, Saberi Karimian, Maryam, Ebrahimi, Mahmoud, Avan, Amir, Eslami, Saied, Pasdar, Alireza, Rooki, Hassan, Esmaeili, Habibollah, Ferns, Gordon A, Ghayour-Mobarhan, Majid

“…Hypertension is an important risk factor for cardiovascular disease and there is increasing evidence that inflammation and abnormal immune responses are…”
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