Search Results - "Pascual‐Salcedo, Dora"

Evaluation of 12 GWAS-drawn SNPs as biomarkers of rheumatoid arthritis response to TNF inhibitors. A potential SNP association with response to etanercept by Ferreiro-Iglesias, Aida, Montes, Ariana, Perez-Pampin, Eva, Cañete, Juan D, Raya, Enrique, Magro-Checa, Cesar, Vasilopoulos, Yiannis, Caliz, Rafael, Ferrer, Miguel Angel, Joven, Beatriz, Carreira, Patricia, Balsa, Alejandro, Pascual-Salcedo, Dora, Blanco, Francisco J, Moreno-Ramos, Manuel J, Manrique-Arija, Sara, Ordoñez, María Del Carmen, Alegre-Sancho, Juan Jose, Narvaez, Javier, Navarro-Sarabia, Federico, Moreira, Virginia, Valor, Lara, Garcia-Portales, Rosa, Marquez, Ana, Gomez-Reino, Juan J, Martin, Javier, Gonzalez, Antonio

“…Research in rheumatoid arthritis (RA) is increasingly focused on the discovery of biomarkers that could enable personalized treatments. The genetic biomarkers…”
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Golimumab Tapering Strategy Based on Serum Drug Levels in Patients With Spondyloarthritis by Redondo, Cristina, Martínez‐Feito, Ana, Plasencia‐Rodríguez, Chamaida, Navarro‐Compán, Victoria, Nuño‐Nuño, Laura, Peiteado, Diana, Villalba, Alejandro, Jochems, Andrea, Pascual‐Salcedo, Dora, Balsa, Alejandro

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Predictive Value of Serum Infliximab Levels at Induction Phase in Rheumatoid Arthritis Patients by Teresa, Jurado, Chamaida, Plasencia-Rodríguez, Ana, Martínez-Feito, Victoria, Navarro-Compán, Theo, Rispens, Annick, Vries, Karien, Bloem, Eva-María, Olariaga, Cristina, Diego, Alejandro, Villalba, Diana, Peiteado, Laura, Nuño, Maria-Gema, Bonilla, Alejandro, Balsa, Dora, Pascual-Salcedo

“…The Infliximab, has proven effective in treating rheumatoid arthritis (RA). A good clinical response is usually associated with high serum drug levels…”
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Improved RA classification among early arthritis patients with the concordant presence of three RA autoantibodies: analysis in two early arthritis clinics by Regueiro, Cristina, Rodríguez-Martínez, Lorena, Nuño, Laura, Ortiz, Ana M, Villalba, Alejandro, Pascual-Salcedo, Dora, Martínez-Feito, Ana, González-Alvaro, Isidoro, Balsa, Alejandro, Gonzalez, Antonio

“…The patients with RA benefit from early identification soon after the first clinical symptoms appear. The 2010 ACR/EULAR classification criteria were developed…”
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Evaluation of Natalizumab Pharmacokinetics and Pharmacodynamics: Toward Individualized Doses by Serra López-Matencio, Jose M., Pérez García, Yaiza, Meca-Lallana, Virginia, Juárez-Sánchez, Raquel, Ursa, Angeles, Vega-Piris, Lorena, Pascual-Salcedo, Dora, de Vries, Annick, Rispens, Theo, Muñoz-Calleja, Cecilia

“…Background: Plasma concentration of natalizumab falls above the therapeutic threshold in many patients who, therefore, receive more natalizumab than necessary…”
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Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis by Hernández-Breijo, Borja, Plasencia-Rodríguez, Chamaida, Navarro-Compán, Victoria, Martínez-Feito, Ana, Jochems, Andrea, Kneepkens, Eva L, Wolbink, Gerrit J, Rispens, Theo, Diego, Cristina, Pascual-Salcedo, Dora, Balsa, Alejandro

“…The aim of our study was to investigate the influence of conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) and body mass index (BMI) on…”
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Value of Measuring Anti-Carbamylated Protein Antibodies for Classification on Early Arthritis Patients by Regueiro, Cristina, Nuño, Laura, Ortiz, Ana M., Peiteado, Diana, Villalba, Alejandro, Pascual-Salcedo, Dora, Martínez-Feito, Ana, González-Alvaro, Isidoro, Balsa, Alejandro, González, Antonio

“…Classification of patients with rheumatoid arthritis (RA) as quickly as possible improves their prognosis. This reason motivates specially dedicated early…”
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Infusion reactions during infliximab treatment are not associated with IgE anti-infliximab antibodies by van Schie, Karin A, Ooijevaar-De Heer, Pleuni, Kruithof, Simone, Plasencia, Chamaida, Jurado, Teresa, Pascual Salcedo, Dora, Brandse, Johannan F, d'Haens, Geert Ram, Wolbink, Gerrit Jan, Rispens, Theo

“…Controversy exists on the role of IgE antidrug antibodies (IgE-ADA) in infusion reactions (IR) on infliximab treatment, partly due to the lack of a positive…”
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Specific Association of HLA–DRB103 With Anti–Carbamylated Protein Antibodies in Patients With Rheumatoid Arthritis by Regueiro, Cristina, Rodríguez‐Rodríguez, Luis, Triguero‐Martinez, Ana, Nuño, Laura, Castaño‐Nuñez, Angel L., Villalva, Alejandro, Pérez‐Pampín, Eva, Lopez‐Golan, Yolanda, Abasolo, Lydia, Ortiz, Ana M., Herranz, Eva, Pascual‐Salcedo, Dora, Martínez‐Feito, Ana, Boveda, María Dolores, Gomez‐Reino, Juan J., Martín, Javier, Gonzalez‐Escribano, María Francisca, Fernández‐Gutiérrez, Benjamín, Balsa, Alejandro, González‐Álvaro, Isodoro, González, Antonio

“…Objective Recognition of a new type of rheumatoid arthritis (RA)–specific autoantibody, the anti–carbamylated protein antibodies (anti‐CarP), has provided an…”
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BAFF predicts immunogenicity in older patients with rheumatoid arthritis treated with TNF inhibitors by Hernández-Breijo, Borja, Navarro-Compán, Victoria, Plasencia-Rodríguez, Chamaida, Parodis, Ioannis, Gehin, Johanna E., Martínez-Feito, Ana, Novella-Navarro, Marta, Mezcua, Araceli, Warren, David J., Nozal, Pilar, Pascual-Salcedo, Dora, Balsa, Alejandro

“…Immunogenicity related to treatment with TNF inhibitors (TNFi) is one of the causes for the decreased attainment of clinical response in patients with…”
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Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis by Lopez-Rodriguez, Rosario, Perez-Pampin, Eva, Marquez, Ana, Blanco, Francisco J, Joven, Beatriz, Carreira, Patricia, Ferrer, Miguel Angel, Caliz, Rafael, Valor, Lara, Narvaez, Javier, Cañete, Juan D, Ordoñez, Maria Del Carmen, Manrique-Arija, Sara, Vasilopoulos, Yiannis, Balsa, Alejandro, Pascual-Salcedo, Dora, Moreno-Ramos, Manuel J, Alegre-Sancho, Juan Jose, Navarro-Sarabia, Federico, Moreira, Virginia, Garcia-Portales, Rosa, Raya, Enrique, Magro-Checa, Cesar, Martin, Javier, Gomez-Reino, Juan J, Gonzalez, Antonio

“…Genetic biomarkers are sought to personalize treatment of patients with rheumatoid arthritis (RA), given their variable response to TNF inhibitors (TNFi)…”
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Influence of rheumatoid factor levels and TNF inhibitor structure on secondary nonresponse in rheumatoid arthritis patients by Plasencia-Rodríguez, Chamaida, Martínez-Feito, Ana, Novella-Navarro, Marta, Pérez De Diego, Rebeca, Bonilla, Gema, Gehin, Johanna Elin, Villalba-Yllán, Alejandro, Nuño, Laura, Pascual-Salcedo, Dora, Nozal, Pilar, Almirón, Mariana Díaz, Balsa, Alejandro

“…The EXXELERATE study revealed poorer clinical outcomes in patients treated with adalimumab (ADL) and baseline rheumatoid factor (RF) above 203 IU/mL. However,…”
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The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case–control samples by Rodríguez‐Rodríguez, Luis, Taib, Wan Rohani Wan, Topless, Ruth, Steer, Sophia, González‐Escribano, María F., Balsa, Alejandro, Pascual‐Salcedo, Dora, González‐Gay, Miguel A., Raya, Enrique, Fernandez‐Gutierrez, Benjamín, González‐Álvaro, Isidoro, Bottini, Nunzio, Witte, Torsten, Viken, Marte K., Coenen, Marieke J. H., van Riel, Piet L. C. M., Franke, Barbara, den Heijer, Martin, Radstake, Timothy R. D. J., Wordsworth, Paul, Lie, Benedicte A., Merriman, Tony R., Martín, Javier

“…Objective Recently, a functional PTPN22 variant (R263Q; rs33996649) was found to be associated with systemic lupus erythematosus (SLE). This study was…”
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Blood Lymphocyte Subsets for Early Identification of Non-Remission to TNF Inhibitors in Rheumatoid Arthritis by Rodríguez-Martín, Eulalia, Nieto-Gañán, Israel, Hernández-Breijo, Borja, Sobrino, Cristina, García-Hoz, Carlota, Bachiller, Javier, Martínez-Feito, Ana, Navarro-Compán, Victoria, Lapuente-Suanzes, Paloma, Bonilla, Gema, Pascual-Salcedo, Dora, Roy, Garbiñe, Jurado, Teresa, Nozal, Pilar, Vázquez-Díaz, Mónica, Balsa, Alejandro, Villar, Luisa M, Plasencia-Rodríguez, Chamaida

“…TNF inhibitors (TNFis) are widely used for the treatment of rheumatoid arthritis (RA), although the response rates to this therapy in patients with RA remains…”
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Coping with rheumatic stressors (CORS) questionnaire: Spanish translation and cross-cultural adaptation by Benavent, Diego, Jochems, Andrea, Pascual-Salcedo, Dora, Jochems, Gijs, Plasencia-Rodríguez, Chamaida, Ramiro, Sofia, van Lankveld, Wim, Balsa, Alejandro, Navarro-Compán, Victoria

“…Background Rheumatic and Musculoskeletal Diseases (RMDs) substantially impact the lives of patients, with complex associations between disease severity and…”
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Antiphosphatidylserine/prothrombin antibodies (aPS/PT) as potential markers of antiphospholipid syndrome by Vlagea, Alexandru, Gil, Antonio, Cuesta, Maria V, Arribas, Florencia, Diez, Jesús, Lavilla, Paz, Pascual-Salcedo, Dora

“…The antiphospholipid antibodies present in antiphospholipid syndrome (APS) are directed at a number of phospholipid-binding proteins: β2 glycoprotein I…”
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Characterization of VLA‐4‐dependent myeloma cell adhesion to fibronectin and VCAM‐1 by Sanz‐Rodríguez, Francisco, Ruiz‐Velasco, Natividad, Pascual‐Salcedo, Dora, Teixidó, Joaquin

“…The integrin VLA‐4 mediates attachment of myeloma cells to multiple myeloma (MM) bone marrow stroma. The alternatively‐spliced CS‐1 region of fibronectin (FN)…”
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Methotrexate Reduces the Probability of Discontinuation of TNF Inhibitors in Seropositive Patients With Rheumatoid Arthritis. A Real-World Data Analysis by Hernández-Breijo, Borja, Brenis, Claudia M., Plasencia-Rodríguez, Chamaida, Martínez-Feito, Ana, Novella-Navarro, Marta, Pascual-Salcedo, Dora, Balsa, Alejandro

“…Tumor necrosis factor inhibitors (TNFi) are widely used for the treatment of patients with rheumatoid arthritis (RA), however a considerable percentage of…”
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Association of CD247 polymorphisms with rheumatoid arthritis: a replication study and a meta-analysis by Teruel, María, McKinney, Cushla, Balsa, Alejandro, Pascual-Salcedo, Dora, Rodriguez-Rodriguez, Luis, Ortiz, Ana M, Gómez-Vaquero, Carmen, González-Gay, Miguel A, Smith, Malcolm, Witte, Torsten, Merriman, Tony, Lie, Benedicte A, Martin, Javier

“…Given the role of CD247 in the response of the T cells, its entailment in autoimmune diseases and in order to better clarify the role of this gene in RA…”
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The TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis by Lamana, Amalia, Balsa, Alejandro, Rueda, Blanca, Ortiz, Ana M, Nuño, Laura, Miranda-Carus, Maria Eugenia, Gonzalez-Escribano, Maria F, Lopez-Nevot, Miguel A, Pascual-Salcedo, Dora, Martin, Javier, González-Álvaro, Isidoro

“…The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked…”
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