Search Results - "Pascual, Ester"
-
1
Toxic and nutritional factors trigger Leber hereditary optic neuropathy due to a mitochondrial tRNA mutation
Published in Clinical genetics (01-10-2022)“…Leber hereditary optic neuropathy is a mitochondrial disease mainly due to pathologic mutations in mitochondrial genes related to the respiratory complex I of…”
Get full text
Journal Article -
2
Understanding the multifactorial control of growth hormone release by somatotropes: lessons from comparative endocrinology
Published in Annals of the New York Academy of Sciences (01-04-2009)“…Control of postnatal growth is the main, but not the only, role for growth hormone (GH) as this hormone also contributes to regulating metabolism,…”
Get full text
Journal Article -
3
Intracellular signaling pathways activated by kisspeptins through GPR54: Do multiple signals underlie function diversity?
Published in Peptides (New York, N.Y. : 1980) (2009)“…Kisspeptins, a family of peptide products derived from the KiSS-1 gene, activate their cognate receptor GPR54 in various target tissues to exert disparate…”
Get full text
Journal Article -
4
From genetics to epigenetics to unravel the etiology of adolescent idiopathic scoliosis
Published in Bone (New York, N.Y.) (01-11-2020)“…Scoliosis is defined as the three-dimensional (3D) structural deformity of the spine with a radiological lateral Cobb angle (a measure of spinal curvature) of…”
Get full text
Journal Article -
5
In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides
Published in Molecular pharmacology (01-07-2009)“…Kisspeptins, the natural ligands of the G protein-coupled receptor KISS1R, comprise a family of related peptides derived from the proteolytic processing of a…”
Get more information
Journal Article -
6
Systemic inflammation, oxidative damage and neurocognition predict telomere length in a transdiagnostic sample stratified by global DNA methylation levels
Published in Scientific reports (07-06-2024)“…Epigenetic mechanisms contribute to the maintenance of both type 2 diabetes mellitus (T2DM) and psychiatric disorders. Emerging evidence suggests that…”
Get full text
Journal Article -
7
The Modest ECtHR Supervision of Spain´s Prison System
Published in Howard journal of crime and justice (01-12-2021)“…The European Court of Human Rights (ECtHR) has not yet ruled against Spain for breaching Article 3 of the European Convention on Human Rights (ECHR) on account…”
Get full text
Journal Article -
8
Cerebrospinal fluid dynamics modulation by diet and cytokines in rats
Published in Fluids and barriers of the CNS (10-02-2020)“…Idiopathic intracranial hypertension (IIH) is a neurological disorder characterised by raised cerebrospinal fluid (CSF) pressure in the absence of any…”
Get full text
Journal Article -
9
Oxidative Stress and the Epigenetics of Cell Senescence: Insights from Progeroid Syndromes
Published in Current pharmaceutical design (01-01-2018)“…Cell senescence constitutes a critical process to respond to a variety of insults and adverse circumstances. Senescence involves the detention of DNA…”
Get more information
Journal Article -
10
Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening
Published in Redox biology (01-04-2018)“…Loss of function of dyskerin (DKC1), NOP10 and TIN2 are responsible for different inheritance patterns of Dyskeratosis congenita (DC; ORPHA1775). They are key…”
Get full text
Journal Article -
11
Understanding the Multifactorial Control of Growth Hormone Release by Somatotropes
Published in Annals of the New York Academy of Sciences (01-04-2009)“…Control of postnatal growth is the main, but not the only, role for growth hormone (GH) as this hormone also contributes to regulating metabolism,…”
Get full text
Journal Article -
12
Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials
Published in Stem cells international (01-01-2017)“…Human dental pulp stem cells (HDPSCs) are of special relevance in future regenerative dental therapies. Characterizing cytotoxicity and genotoxicity produced…”
Get full text
Journal Article -
13
Functional and structural neuroretinal disorders in HIV Controllers. Prospective cohort study
Published in HIV medicine (01-11-2024)“…Objective To estimate the prevalence and cumulative incidence of neuro‐retinal‐disorders (NRD) in HIV‐controllers. Design Prospective, single‐centre, cohort…”
Get full text
Journal Article -
14
Investigation into the Choroid Plexus Molecular Mechanisms Underlying Idiopathic Intracranial Hypertension
Published 01-01-2021“…Idiopathic Intracranial Hypertension (IIH) is a rare condition characterised by increased intracranial pressure for unknown reasons. It predominantly affects…”
Get full text
Dissertation -
15
Somatotropinomas, But Not Nonfunctioning Pituitary Adenomas, Maintain a Functional Apoptotic RET/Pit1/ARF/p53 Pathway That Is Blocked by Excess GDNF
Published in Endocrinology (Philadelphia) (01-11-2014)“…Acromegaly is caused by somatotroph cell adenomas (somatotropinomas [ACROs]), which secrete GH. Human and rodent somatotroph cells express the RET receptor. In…”
Get full text
Journal Article -
16