Search Results - "Pascua, Laura"

Genetic basis of infectivity evolution in a bacteriophage by SCANLAN, PAULINE D., HALL, ALEX R., LOPEZ-PASCUA, LAURA D. C., BUCKLING, ANGUS

“…Antagonistic coevolution between hosts and parasites is probably ubiquitous. However, very little is known of the genetic changes associated with parasite…”
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Higher resources decrease fluctuating selection during host–parasite coevolution by Lopez Pascua, Laura, Hall, Alex R, Best, Alex, Morgan, Andrew D, Boots, Mike, Buckling, Angus, Fukami, Tadashi

“…We still know very little about how the environment influences coevolutionary dynamics. Here, we investigated both theoretically and empirically how nutrient…”
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Mycobacterium tuberculosis Up-Regulates Matrix Metalloproteinase-1 Secretion from Human Airway Epithelial Cells via a p38 MAPK Switch by Elkington, Paul T. G, Emerson, Jenny E, Lopez-Pascua, Laura D. C, O'Kane, Cecilia M, Horncastle, Donna E, Boyle, Joseph J, Friedland, Jon S

“…Pulmonary cavitation is vital to the persistence and spread of Mycobacterium tuberculosis (MTb), but mechanisms underlying this lung destruction are poorly…”
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Differential impact of simultaneous migration on coevolving hosts and parasites by Morgan, Andrew D, Brockhurst, Michael A, Lopez-Pascua, Laura D C, Pal, Csaba, Buckling, Angus

“…The dynamics of antagonistic host-parasite coevolution are believed to be crucially dependent on the rate of migration between populations. We addressed how…”
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Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia by Klintman, Jenny, Appleby, Niamh, Stamatopoulos, Basile, Ridout, Katie, Eyre, Toby A., Robbe, Pauline, Pascua, Laura Lopez, Knight, Samantha J.L., Dreau, Helene, Cabes, Maite, Popitsch, Niko, Ehinger, Mats, Martín-Subero, Jose I., Campo, Elías, Månsson, Robert, Rossi, Davide, Taylor, Jenny C., Vavoulis, Dimitrios V., Schuh, Anna

“…The transformation of chronic lymphocytic leukemia (CLL) to high-grade B-cell lymphoma is known as Richter syndrome (RS), a rare event with dismal prognosis…”
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Precision medicine for patients with lymphoma; the Bloodwise Precision Medicine for Aggressive Lymphomas (PMAL) consortium by Merron, Bridgin, Kazmi-Stokes, Shamim, Cummin, Thomas, Barrans, Sharon, Araf, Shamzah, Korfi, Koorosh, Pascua, Laura D Lopez, Caddy, Josh, Cozens, Kelly, Cucco, Francesco, Uddin, Rahman, Sha, Chulin, Tooze, Reuben, Griffiths, Gareth, Du, Ming Qing, Burton, Cathy, Westhead, David, Fitzgibbon, Jude, Schuh, Anna, Davies, Andrew, Johnson, Peter

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Synergistic Up-Regulation of Epithelial Cell Matrix Metalloproteinase-9 Secretion in Tuberculosis by Elkington, Paul T, Green, Justin A, Emerson, Jenny E, Lopez-Pascua, Laura D, Boyle, Joseph J, O'Kane, Cecilia M, Friedland, Jon S

“…Mycobacterium tuberculosis (MTb) kills approximately 2 million people each year. MTb must drive host tissue destruction to disseminate and also to cause…”
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Interim Cell-Free Circulating Lymphoma DNA Analysis of the Phase 2 Accept Trial by Cutts, Anthony, Wilson, Edward, Tang, Pek Sang, Davies, Andrew, Johnson, Peter, Stanton, Louise, Mercer, Katy, Caddy, Josh, Schuh, Anna, Lopez Pascua, Laura, Dreau, Helene Marie-Pierre

“…Introduction Plasma cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA) genotyping in Diffuse Large B-cell Lymphoma (DLBCL) holds great promise for early…”
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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features by Robbe, Pauline, Ridout, Kate E., Vavoulis, Dimitrios V., Dréau, Helene, Kinnersley, Ben, Denny, Nicholas, Chubb, Daniel, Appleby, Niamh, Cutts, Anthony, Cornish, Alex J., Lopez-Pascua, Laura, Clifford, Ruth, Burns, Adam, Stamatopoulos, Basile, Cabes, Maite, Alsolami, Reem, Antoniou, Pavlos, Oates, Melanie, Cavalieri, Doriane, Gibson, Jane, Prabhu, Anika V., Schwessinger, Ron, Jennings, Daisy, James, Terena, Maheswari, Uma, Duran-Ferrer, Martí, Carninci, Piero, Knight, Samantha J. L., Månsson, Robert, Hughes, Jim, Davies, James, Ross, Mark, Bentley, David, Strefford, Jonathan C., Devereux, Stephen, Pettitt, Andrew R., Hillmen, Peter, Caulfield, Mark J., Houlston, Richard S., Martín-Subero, José I., Schuh, Anna

“…The value of genome-wide over targeted driver analyses for predicting clinical outcomes of cancer patients is debated. Here, we report the whole-genome…”
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Genomic and transcriptomic correlates of Richter's transformation in Chronic Lymphocytic Leukemia by Klintman, Jenny, Appleby, Niamh, Stamatopoulos, Basile, Ridout, Kate, Eyre, Toby Andrew, Robbe, Pauline, Lopez Pascua, Laura, Knight, Samantha Jl, Dreau, Helene Mp, Cabes, Maite, Popitsch, Niko, Ehinger, Mats, Martin-Subero, Iñaki, Campo, Elías, Mansson, Robert, Rossi, Davide, Taylor, Jenny C, Vavoulis, Dimitrios V, Schuh, Anna

“…The transformation of chronic lymphocytic leukemia (CLL) to high-grade B-cell lymphoma is known as Richter's Syndrome (RS) and it is a rare event with dismal…”
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Lithium-deficient LiyMn204 spinels (0.9 < Y < 1): Lithium content, synthesis temperature, thermal behaviour and electrochemical properties by Pascua, Laura, Perez-Reveng, M Luz, Rojas, Rosa M, Rojo, Jose M, Amarilla, J Manuel

“…Lithium-deficient LiyMn204 spinels (LD-LiyMn204) with nominal composition (0.9 < Y < 1) have been synthesized by melt impregnation from Mn203 and LiNO3 at…”
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