Search Results - "Pascoe, Steven"
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Clinical Course and Management of Hypertrophic Cardiomyopathy
Published in The New England journal of medicine (15-11-2018)Get full text
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FULFIL Trial: Once-Daily Triple Therapy for Patients with Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-08-2017)“…Randomized data comparing triple therapy with dual inhaled corticosteroid (ICS)/long-acting β -agonist (LABA) therapy in patients with chronic obstructive…”
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Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD
Published in The New England journal of medicine (03-05-2018)“…The frequency of COPD exacerbations during treatment with a triple inhaler — delivering a long-acting beta-agonist (LABA), a long-acting muscarinic antagonist…”
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Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials
Published in The lancet respiratory medicine (01-06-2015)“…Summary Background The short-term benefits of inhaled corticosteroids for patients with chronic obstructive pulmonary disease (COPD) are greater in patients…”
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Reduction in All-Cause Mortality with Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-06-2020)“…The IMPACT (Informing the Pathway of Chronic Obstructive Pulmonary Disease Treatment) trial demonstrated a significant reduction in all-cause mortality (ACM)…”
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Blood eosinophil levels as a biomarker in COPD
Published in Respiratory medicine (01-05-2018)“…Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder and patients respond differently to treatment. Blood eosinophils are a potential…”
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Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone
Published in The New England journal of medicine (12-05-2016)“…Among more than 11,000 patients with moderate-to-severe asthma, fluticasone–salmeterol was noninferior to fluticasone alone with respect to severe asthma…”
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A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol
Published in The European respiratory journal (01-08-2016)“…Patients with symptomatic advanced chronic obstructive pulmonary disease (COPD) who experience recurrent exacerbations are particularly at risk of poor…”
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Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma
Published in The New England journal of medicine (01-09-2016)“…This large trial involving children with asthma examined whether the addition of a long-acting beta-agonist to current therapy with inhaled glucocorticoids…”
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Understanding asthma-chronic obstructive pulmonary disease overlap syndrome
Published in Respiratory medicine (01-01-2016)“…Abstract Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) is a loosely-defined clinical entity referring to patients who exhibit…”
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Circulating neutrophils levels are a predictor of pneumonia risk in chronic obstructive pulmonary disease
Published in Respiratory research (23-08-2019)“…Patients with chronic obstructive pulmonary disease (COPD) have excess risk of developing pneumonia; however, no definitive biomarkers of risk have been…”
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Clinical Course and Management of Hypertrophic Cardiomyopathy
Published in The New England journal of medicine (15-11-2018)“…To the Editor: In his review article, Maron (Aug. 16 issue) 1 does not mention the potential of physical examination in patients with hypertrophic…”
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The Significance of Eosinophilic Inflammation in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-04-2018)Get full text
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No dose effect observed with chronic fluticasone propionate on growth velocity in children
Published in Pediatric allergy and immunology (01-02-2021)Get full text
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Reliability, validity and responsiveness of E-RS:COPD in patients with spirometric asthma-COPD overlap
Published in Respiratory research (31-05-2019)“…The Evaluating Respiratory Symptoms in Chronic Obstructive Pulmonary Disease (E-RS:COPD) is a patient-reported diary that assesses respiratory symptoms in…”
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A phase IIb, randomised, parallel-group study: the efficacy, safety and tolerability of once-daily umeclidinium in patients with asthma receiving inhaled corticosteroids
Published in Respiratory research (12-06-2020)“…Patients with asthma uncontrolled on inhaled corticosteroids may benefit from umeclidinium (UMEC), a long-acting muscarinic antagonist. This Phase IIb,…”
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Reply to Suissa and Ariel: The FULFIL Trial
Published in American journal of respiratory and critical care medicine (15-02-2018)Get full text
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Anaemia and iron dysregulation: untapped therapeutic targets in chronic lung disease?
Published in BMJ Open Respiratory Research (2019)“…Hypoxia is common in many chronic lung diseases. Beyond pulmonary considerations, delivery of oxygen (O2) to the tissues and subsequent O2 utilisation is also…”
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