Tracheoesophageal anastomosis, continent gastrostomy and oesophagostomy--a new experimental model in minipiglets

Tracheoesophageal anastomosis, continent gastrostomy and oesophagostomy--a new experimental model in minipiglets

Tracheoesophageal fistulae endanger newborn children by aspiration pneumonia. An animal model of this dangerous malformation was thought to be impossible until now. By tracheoesophageal anastomosis, occlusion of the oesophagogastral junction, proximal cervical oesophagostomy and continent gastrostom...

Full description

Saved in:
Bibliographic Details
Published in:Laboratory animals (London) Vol. 29; no. 4; pp. 411 - 419
Main Authors: Schaarschmidt, K, Paschertz, K.W, Stratmann, U, Ruprecht, L, Willital, G.H, Unsold, E
Format: Journal Article
Language:English
Published: London, England SAGE Publications 01-10-1995
Subjects:
abnormal development
anastomosis
Anastomosis, Surgical - veterinary
animal models
Animals
Animals, Laboratory - surgery
Body Weight
Diet
disease models
Disease Models, Animal
enteral feeding
Enteral Nutrition
esophageal atresia
Esophageal Atresia - pathology
Esophagostomy - veterinary
esophagus
Esophagus - surgery
experimental surgery
fistula
Gastrostomy - veterinary
laboratory mammals
Male
miniature swine
piglets
restricted feeding
surgery
Swine
Swine, Miniature - surgery
trachea (vertebrates)
Trachea - surgery
tracheoesophageal fistula
Tracheoesophageal Fistula - surgery
TRACHEOESOPHAGEAL FISTULA
OESOPHAGOSTOMY
MINIPIG
ISOFLURANE ANAESTHESIA
OESOPHAGUS
CONTINENT GASTROSTOMY
ALIMENTARY ABSTINENCE
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Tracheoesophageal fistulae endanger newborn children by aspiration pneumonia. An animal model of this dangerous malformation was thought to be impossible until now. By tracheoesophageal anastomosis, occlusion of the oesophagogastral junction, proximal cervical oesophagostomy and continent gastrostomy in 25 minipiglets a reliable model of tracheaesophageal fistula has been developed. After establishing the model in a pilot study the mortality following the establishment of this procedure was 5.6% and the minipiglets survived in excellent condition for 2-10 week periods under complete alimentary restriction and gastrostomy feeding. Therefore the method seems to be suitable for long-term investigations on major oesophagotracheal surgery.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0023-6772
1758-1117
DOI:10.1258/002367795780740131