Search Results - "Pascha, Mirte N."

Influenza Neuraminidase Characteristics and Potential as a Vaccine Target by Creytens, Sarah, Pascha, Mirte N, Ballegeer, Marlies, Saelens, Xavier, de Haan, Cornelis A M

“…Neuraminidase of influenza A and B viruses plays a critical role in the virus life cycle and is an important target of the host immune system. Here, we…”
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Dorsal Root Ganglia Macrophages Maintain Osteoarthritis Pain by Raoof, Ramin, Martin Gil, Christian, Lafeber, Floris P J G, de Visser, Huub, Prado, Judith, Versteeg, Sabine, Pascha, Mirte N, Heinemans, Anne L P, Adolfs, Youri, Pasterkamp, Jeroen, Wood, John N, Mastbergen, Simon C, Eijkelkamp, Niels

“…Pain is the major debilitating symptom of osteoarthritis (OA), which is difficult to treat. In OA patients joint tissue damage only poorly associates with…”
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Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis by Liu, Minglong, Morewood, Richard, Yoshisada, Ryoji, Pascha, Mirte N, Hopstaken, Antonius J. P, Tarcoveanu, Eliza, Poole, David A, de Haan, Cornelis A. M, Nitsche, Christoph, Jongkees, Seino A. K

“…Peptide display technologies are a powerful method for discovery of new bioactive sequences, but linear sequences are often very unstable in a biological…”
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An Efficient, Site‐Selective and Spontaneous Peptide Macrocyclisation During in vitro Translation by Liu, Minglong, Yoshisada, Ryoji, Amedi, Avand, Hopstaken, Antonius J. P., Pascha, Mirte N., Haan, Cornelis A. M., Geerke, Daan P., Poole, David A., Jongkees, Seino A. K.

“…Macrocyclisation provides a means of stabilising the conformation of peptides, often resulting in improved stability, selectivity, affinity, and cell…”
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Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region by Pascha, Mirte N., Thijssen, Vito, Egido, Julia E., Linthorst, Mirte W., van Lanen, Jipke H., van Dongen, David A. A., Hopstaken, Antonius J. P., van Kuppeveld, Frank J. M., Snijder, Joost, de Haan, Cornelis A. M., Jongkees, Seino A. K.

“…Influenza A viruses pose a serious pandemic risk, while generation of efficient vaccines against seasonal variants remains challenging. There is thus a…”
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