Search Results - "Pascaud, Antoine"
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Short‐ and long‐term administration of the non‐steroidal mineralocorticoid receptor antagonist finerenone opposes metabolic syndrome‐related cardio‐renal dysfunction
Published in Diabetes, obesity & metabolism (01-10-2018)“…Aim To determine whether non‐steroidal mineralocorticoid receptor (MR) antagonists oppose metabolic syndrome‐related end‐organ, i.e. cardiac, damage. Materials…”
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Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice
Published in The FASEB journal (01-08-2014)“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
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Antifibrotic effect of novel neutrophil gelatinase-associated lipocalin inhibitors in cardiac and renal disease models
Published in Scientific reports (28-01-2021)“…Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological…”
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Unraveling the morphological diversity of P(VDF-ter-TrFE-ter-CTFE) semi-crystalline terpolymers via combined AFM and SAXS experiments
Published in Polymer testing (01-03-2023)“…In this article, the diverse morphologies observed after annealing or crystallization from the melt in P(VDF-ter-TrFE-ter-CTFE) terpolymers with varying CTFE…”
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Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice
Published in ESC Heart Failure (01-06-2021)“…Aims In post‐menopausal women, incidence of heart failure with preserved ejection fraction is higher than in men. Hormonal replacement therapies did not…”
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Pour une définition de la notion de « langue régionale
Published in Lengas (Montpellier, Centre d'études occitanes, Université Paul Valéry) (16-10-2017)“…The notion of regional language has spread for half a century, particularly in Europe, although we also find it in India where it applies to co-official…”
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Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction
Published in Hypertension (Dallas, Tex. 1979) (01-04-2016)“…Mineralocorticoid receptor (MR) antagonists slow down the progression of heart failure after myocardial infarction (MI), but the cell-specific role of MR in…”
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Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness
Published in Hypertension (Dallas, Tex. 1979) (01-03-2014)“…Arterial stiffness is recognized as a risk factor for many cardiovascular diseases. Aldosterone via its binding to and activation of the mineralocorticoid…”
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Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction
Published in ESC Heart Failure (01-04-2021)“…Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by…”
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Myocardial Injury After Ischemia/Reperfusion Is Attenuated By Pharmacological Galectin-3 Inhibition
Published in Scientific reports (03-07-2019)“…Although optimal therapy for myocardial infarction includes reperfusion to restore blood flow to the ischemic region, ischemia/reperfusion (IR) also initiates…”
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Mineralocorticoid receptor antagonism improves diastolic dysfunction in chronic kidney disease in mice
Published in Journal of molecular and cellular cardiology (01-08-2018)“…Managing the cardiovascular complications of renal failure is a major therapeutic challenge in clinical practice. Mineralocorticoid Receptor (MR) blockade is a…”
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Aldosterone promotes cardiac endothelial cell proliferation in vivo
Published in Journal of the American Heart Association (06-01-2015)“…Experimentally, aldosterone in association with NaCl induces cardiac fibrosis, oxidative stress, and inflammation through mineralocorticoid receptor…”
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Pour une définition de la notion de minorité linguistique : les difficultés du vague
Published in Lengas (Montpellier, Centre d'études occitanes, Université Paul Valéry) (01-11-2018)“…In this paper we try and provide a definition of the notion of minorité linguistique (“linguistic minority”). The main conceptual difficulty attached to this…”
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Aldosterone-Specific Activation of Cardiomyocyte Mineralocorticoid Receptor In Vivo
Published in Hypertension (Dallas, Tex. 1979) (01-02-2013)“…Inappropriate mineralocorticoid receptor (MR) activation is involved in cardiac diseases. Whether and how aldosterone is involved in the deleterious effects of…”
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BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice
Published in Cell death & disease (15-08-2023)“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
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Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B
Published in Journal of molecular and cellular cardiology (01-06-2012)“…Abstract Protein tyrosine phosphatase 1B (PTP1B) regulates tyrosine kinase receptor-mediated responses, and especially negatively influences insulin…”
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Coronary endothelial dysfunction after cardiomyocyte-specific mineralocorticoid receptor overexpression
Published in American journal of physiology. Heart and circulatory physiology (01-06-2011)“…The deleterious effects of aldosterone excess demonstrated in cardiovascular diseases might be linked in part to coronary vascular dysfunction. However,…”
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Conditional Transgenic Mice for Studying the Role of the Glucocorticoid Receptor in the Renal Collecting Duct
Published in Endocrinology (Philadelphia) (01-05-2009)“…The mineralocorticoid receptor (MR) is a major regulator of renal sodium reabsorption and body fluid homeostasis. However, little is known about glucocorticoid…”
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Миноритарный Язык, Минорируемый Язык, Миноризируемый Язык Или Язык В Миноритарной Ситуации? Опыт Дефиниции И Использования В Ситуации [Minority Languages, Marginalized Languages, Minoritized Languages or Language in a Minoritial Situation? Attempted Definition and Performances]
Published in Vestnik Rossijskogo universiteta družby narodov. Seriâ: Teoriâ âzyka, semiotika, semantika (Online) (2017)“…The article presents a sociolinguistic typology of languages that make up the categorical field of a linguistic minority. Meanings and connotations behind such…”
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Managing cardio-renal-metabolic risk in patients with type 2 diabetes: the role of finerenone
Published in Journal of diabetes and its complications (01-05-2024)“…•Diabetic kidney disease (DKD) develops in nearly 40% of patients with diabetes, and is a leading cause of end-stage renal disease…”
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