Search Results - "Pascarella, S"

Genomic distribution and heterogeneity of MocR-like transcriptional factors containing a domain belonging to the superfamily of the pyridoxal-5′-phosphate dependent enzymes of fold type I by Bramucci, E., Milano, T., Pascarella, S.

“…[Display omitted] ► MocR distribution in complete proteomes is heterogeneous. ► Presence of MocR regulators is correlated to genome size. ► Minimum genome size…”
Get full text

773 HEPATITIS C VIRUS AND LIPID DROPLETS: ROLE OF SEIPIN IN LIPID DROPLET MATURATION AND VIRAL LIFE CYCLE by Clement, S, Fauvelle, C, Pascarella, S, Conzelmann, S, Kaddai, V, Minehira, K, Negro, F

Get full text

795 HEPATITIS C VIRUS AND THE METABOLIC SYNDROME: CROSS-TALK BETWEEN INFECTED AND UNINFECTED CELLS by Kaddai, V, Clément, S, Pascarella, S, Guilloux, K, Conzelmann, S, Negro, F

Get full text

CAMPO, SCR_FIND and CHC_FIND: a suite of web tools for computational structural biology by Paiardini, Alessandro, Bossa, Francesco, Pascarella, Stefano

“…The identification of evolutionarily conserved features of protein structures can provide insights into their functional and structural properties. Three…”
Get full text

885 INTRAHEPATIC MRNA LEVELS OF THE SUPPRESSORS OF CYTOKINE SIGNALLING 1 AND 3 ARE ASSOCIATED WITH CIRRHOSIS BUT NOT WITH TREATMENT RESPONSE IN CHRONIC HEPATITIS C by Clement, S, Pascarella, S, Dill, M.T, Conzelmann, S, Lagging, M, Missale, G, Neumann, A.U, Pawlotsky, J.-M, Zeuzem, S, Bochud, P.-Y, Negro, F

Get full text

Structural analysis of toxic volkensin, a type 2 ribosome inactivating protein from Adenia volkensii Harm (kilyambiti plant): Molecular modeling and surface analysis by computational methods and limited proteolysis by Severino, V., Paiardini, A., Pascarella, S., Parente, A., Chambery, A.

“…Volkensin, isolated from Adenia volkensii, is one of the most toxic type 2 ribosome-inactivating protein (RIP), exerting its biological function by inhibiting…”
Get full text

Improvement in prediction of solvent accessibility by probability profiles by Gianese, Giulio, Bossa, Francesco, Pascarella, Stefano

“…The capability of predicting folding and conformation of a protein from its primary structure is probably one of the main goals of modern biology. An accurate…”
Get full text

810 DOWNREGULATION OF PTEN AND IRS1 BY HCV 3A CORE PROTEIN TRIGGERS STEATOSIS IN HEPATOCYTES by Peyrou, M, Clément, S, Sanchez-Pareja, A, Bourgoin, L, Suter, D, Vinciguerra, M, Guilloux, K, Pascarella, S, Rubbia-Brandt, L, Negro, F, Foti, M

Get full text

Breast Tumor Malignancy Classification using Smartphone Compression-induced Sensing System and Deformation Index Ratio by Choi, S., Oleksyuk, V., Caroline, D., Pascarella, S., Kendzierski, R., Won, C.-H.

“…Smartphone-based compression-induced sensing system uses the light diffusion pattern to characterize the early-stage breast tumor noninvasively. The system is…”
Get full text

BSTI, a trypsin inhibitor from skin secretions of bombina bombina related to protease inhibitors of nematodes by Mignogna, Giuseppina, Pascarella, Stefano, Amiconi, Gino, Barra, Donatella, Wechselberger, Christian, Hinterleitner, Christa, Mollay, Christa, Kreil, Günther

“…From skin secretions of the European frog Bombina bombina, a new peptide has been isolated that contains 60 amino acids, including 10 cysteine residues. Its…”
Get full text

Quantification of secondary structure prediction improvement using multiple alignments by Levin, J M, Pascarella, S, Argos, P, Garnier, J

“…The use of multiple sequence alignments for secondary structure predictions is analysed. Seven different protein families, containing only sequences of known…”
Get more information

Active site model for γ‐aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities by Toney, Michael D., Pascarella, Stefano, De Biase, Daniela

“…A homology model for the pig isozyme of the pyridoxal phosphate‐dependent enzyme γ‐aminobutyrate (GABA) aminotransferase has been built based mainly on the…”
Get full text

Similarity between pyridoxal/pyridoxamine phosphate‐dependent enzymes involved in dideoxy and deoxyaminosugar biosynthesis and other pyridoxal phosphate enzymes by Pascarella, Stefano, Bossa, Francesco

“…A multiple sequence alignment among aspartate aminotransferase, dialkylglycine decarboxylase, and serine hydroxymethyltransferase (DAS) was used for profile…”
Get full text

The structure of serine hydroxymethyltransferase as modeled by homology and validated by site‐directed mutagenesis by Pascarella, Stefano, Angelaccio, Sebastiana, Contestabile, Roberto, Fratte, Sonia Delle, Salvo, Martino Di, Bossa, Francesco

“…We describe a model for the three‐dimensional structure of E. coli serine hydroxymethyltransferase based on its sequence homology with other PLP enzymes of…”
Get full text

Stability of aspartate aminotransferase from Sulfolobus solfataricus by Arnone, M I, Birolo, L, Pascarella, S, Cubellis, M V, Bossa, F, Sannia, G, Marino, G

“…Aspartate aminotransferase from Sulfolobus solfataricus (SsAspAT) is an extremely thermophilic and thermostable dimeric enzyme which retains its structure and…”
Get full text

Comparative structural analysis of psychrophilic and meso- and thermophilic enzymes by Gianese, Giulio, Bossa, Francesco, Pascarella, Stefano

“…Enzymes adapted to cold display structures comparable with those of their meso‐ and thermophilic homologs but are characterized by a higher catalytic…”
Get full text

The primary structure of rabbit liver cytosolic serine hydroxymethyltransferase by Martini, F., Angelaccio, S., Pascarella, S., Barra, D., Bossa, F., Schirch, V.

“…The complete amino acid sequence of cytosolic serine hydroxymethyltransferase from rabbit liver was determined. The sequence was determined from analysis of…”
Get full text

The Primary Structure of Rabbit Liver Mitochondrial Serine Hydroxymethyltransferase by Martini, F, Maras, B, Tanci, P, Angelaccio, S, Pascarella, S, Barra, D, Bossa, F, Schirch, V

“…The complete amino acid sequence of mitochondrial serine hydroxymethyltransferase from rabbit liver was determined. The sequence was obtained from analysis of…”
Get full text

Serine hydroxymethyltransferase from the cold adapted microorganism Psychromonas ingrahamii: a low temperature active enzyme with broad substrate specificity by Angelaccio, Sebastiana, Florio, Rita, Consalvi, Valerio, Festa, Guido, Pascarella, Stefano

“…Serine hydroxymethyltransferase from the psychrophilic microorganism Psychromonas ingrahamii was expressed in Escherichia coli and purified as a His-tag fusion…”
Get full text

Hepatitis C virus infection: molecular pathways to steatosis, insulin resistance and oxidative stress by Clément, Sophie, Pascarella, Stéphanie, Negro, Francesco

“…The persistent infection with hepatitis C virus is a major cause of chronic liver disease worldwide. However, the morbidity associated with hepatitis C virus…”
Get full text