Search Results - "Pascall, J C"

Heparin-binding epidermal-growth-factor-like growth factor gene expression is induced by scrape-wounding epithelial cell monolayers: involvement of mitogen-activated protein kinase cascades by Ellis, P D, Hadfield, K M, Pascall, J C, Brown, K D

“…Peptide growth factors can promote the cell migration and proliferation that is needed to repair epithelia after mechanical or chemical injury. We report here…”
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Post-transcriptional regulation of gene expression by androgens: recent observations from the epidermal growth factor gene by Pascall, J C

“…Steroid hormones generally mediate their effects by interacting with specific receptors which then bind to defined DNA sequences in the regulatory regions of…”
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Tissue distribution of mRNA for heparin-binding epidermal growth factor by VAUGHAN, T. J, PASCALL, J. C, BROWN, K. D

“…Heparin-binding epidermal growth factor (HB-EGF) is a recently identified member of the EGF family. Mature HB-EGF is processed from a larger transmembrane…”
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Apicomplexan rhomboids have a potential role in microneme protein cleavage during host cell invasion by Dowse, Timothy J., Pascall, John C., Brown, Kenneth D., Soldati, Dominique

“…Apicomplexan parasites secrete transmembrane (TM) adhesive proteins as part of the process leading to host cell attachment and invasion. These microneme…”
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The nucleotide sequence of a cDNA encoding an EGF-inducible gene indicates the existence of a new family of mitogen-induced genes by Gomperts, M, Pascall, J C, Brown, K D

“…A gene, cMG1, whose expression is transiently activated in growth factor stimulated epithelial cells has been identified by differential screening. Overlapping…”
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Expression of the genes for TGF alpha, EGF and the EGF receptor during early pig development by VAUGHAN, T. J, JAMES, P. S, PASCALL, J. C, BROWN, K. D

“…Expression of mRNA for transforming growth factor-alpha (TGF-alpha), epidermal growth factor (EGF) and the epidermal growth factor receptor (EGF-R) during…”
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Cloning and characterization of a gene encoding pig epidermal growth factor by Pascall, J C, Jones, D S, Doel, S M, Clements, J M, Hunter, M, Fallon, T, Edwards, M, Brown, K D

“…A portion of the pig epidermal growth factor (EGF) gene has been isolated and characterized. The nucleotide sequencies of exons 20 and 21, which encode the EGF…”
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Epidermal growth factor concentrations in pig tissues and body fluids measured using a homologous radioimmunoassay by Vaughan, T J, Littlewood, C J, Pascall, J C, Brown, K D

“…A homologous radioimmunoassay for the measurement of epidermal growth factor (EGF) levels in pig tissues and body fluids has been developed using an antiserum…”
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Directed expression of simian virus 40 T-antigen in transgenic mice using the epidermal growth factor gene promoter by Pascall, I C, Surani, M A, Barton, S C, Vaughan, T J, Brown, K D

“…A transgenic mouse line (EGF/Tag) has been established in which expression of SV40 T-antigen is directed by a 5.5 kb fragment of the 5'-flanking region of the…”
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Expression of epidermal growth factor and its mRNA in pig kidney, pancreas and other tissues by VAUGHAN, T. J, PASCALL, J. C, JAMES, P. S, BROWN, K. D

“…The levels of epidermal growth factor (EGF) mRNA in a wide range of pig tissues were measured by a RNAase-protection assay. The highest levels were found in…”
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Molecular cloning and tissue distribution of pig transforming growth factor α by VAUGHAN, T. J, JAMES, P. S, PASCALL, J. C, BROWN, K. D

“…Transforming growth factor alpha (TGF alpha) was originally identified as a product of tumour tissues and transformed cells in culture. Although it is now…”
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Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization by Howes, E, Pascall, J C, Engel, W, Jones, R

“…The mouse zona pellucida glycoprotein, mZP2, is thought to be the secondary receptor on eggs for retention of acrosome-reacted sperm during fertilization…”
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Structural analysis of the 5'-flanking sequence of the mouse epidermal growth factor gene by Pascall, J C, Brown, K D

“…The 5'-flanking sequence of the mouse epidermal growth factor gene has been isolated from a mouse genomic DNA library. S1 nuclease mapping indicated that the…”
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cDNA sequence of human β-preprotachykinin, the common precursor to substance P and neurokinin A by Harmar, A.J., Armstrong, A., Pascall, J.C., Chapman, K., Rosie, R., Curtis, A., Going, J., Edwards, C.R.W., Fink, G.

“…The nucleotide sequence of cDNA encoding the human substance P precursor, β-preprotachykinin (β-PPT), has been determined. The source of mRNA was a human…”
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Tissue-specific effects of castration and ovariectomy on murine epidermal growth factor and its mRNA by Pascall, J C, Saunders, J, Blakeley, D M, Laurie, M S, Brown, K D

“…The polypeptide mitogen, epidermal growth factor (EGF), was originally isolated from mouse submaxillary gland (SMG). In mice, these glands are sexually…”
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Identification of a functional promoter element in the 5'-flanking region of the rat cMG1/TIS11b gene by Corps, A N, Pascall, J C, Hadfield, K M, Brown, K D

“…The cMG1 gene was originally identified as a mitogen-stimulated primary response gene. However, in contrast to genes such as c-fos and TIS11, cMG1 is also…”
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Mitogen-induced expression of the primary response gene cMG1 in a rat intestinal epithelial cell-line (RIE-1) by Gomperts, Miranda, Corps, Anthony N., Pascall, John C., Brown, Kenneth D.

“…cMG1 is a primary response gene first identified in a rat intestinal epithelial (RIE-1)cell-line[(1990) Oncogene 5, 1081–1083]. A number of mitogens, including…”
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Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid by Pascall, John C., Brown, Kenneth D.

“…The Drosophila regulatory protein Rhomboid has been demonstrated genetically to facilitate signalling within the Spitz/epidermal growth factor…”
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Expression in mammalian cell cultures reveals interdependent, but distinct, functions for Star and Rhomboid proteins in the processing of the Drosophila transforming-growth-factor-alpha homologue Spitz by Pascall, John C, Luck, Jane E, Brown, Kenneth D

“…We report here distinct interdependent functions for two proteins, Star and Rhomboid, that are key determinants of the epidermal-growth-factor (EGF)-receptor…”
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Nucleotide sequence and tissue distribution of mouse transforming growth factor-alpha by Vaughan, T J, Pascall, J C, Brown, K D

“…Transforming growth factor-alpha (TGF alpha) is secreted into the medium of the Moloney murine sarcoma virus-transformed 3T3 cell line, 3B11-1C. Using reverse…”
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