Search Results - "Parviz Minoo"
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Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis
Published in American journal of respiratory and critical care medicine (15-01-2020)“…Alveolar epithelial cell (AEC) injury and dysregulated repair are implicated in the pathogenesis of pulmonary fibrosis. Endoplasmic reticulum (ER) stress in…”
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2
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis
Published in The Journal of clinical investigation (01-03-2018)“…Claudins, the integral tight junction (TJ) proteins that regulate paracellular permeability and cell polarity, are frequently dysregulated in cancer; however,…”
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3
Non-canonical WNT signalling in the lung
Published in Journal of biochemistry (Tokyo) (01-11-2015)“…The role of WNT signalling in metazoan organogenesis has been a topic of widespread interest. In the lung, while the role of canonical WNT signalling has been…”
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4
Fgf10-positive cells represent a progenitor cell population during lung development and postnatally
Published in Development (Cambridge) (15-01-2014)“…The lung mesenchyme consists of a widely heterogeneous population of cells that play crucial roles during development and homeostasis after birth. These cells…”
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5
Identification of a novel subset of alveolar type 2 cells enriched in PD-L1 and expanded following pneumonectomy
Published in The European respiratory journal (04-11-2021)“…Alveolar type 2 (AT2) cells are heterogeneous cells, with specialised AT2 subpopulations within this lineage exhibiting stem cell properties. However, the…”
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6
Decoding the IGF1 signaling gene regulatory network behind alveologenesis from a mouse model of bronchopulmonary dysplasia
Published in eLife (10-10-2022)“…Lung development is precisely controlled by underlying gene regulatory networks (GRN). Disruption of genes in the network can interrupt normal development and…”
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Progenitors of Secondary Crest Myofibroblasts Are Developmentally Committed in Early Lung Mesoderm
Published in Stem cells (Dayton, Ohio) (01-03-2015)“…Development of the mammalian lung is predicated on cross‐communications between two highly interactive tissues, the endodermally derived epithelium and the…”
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8
Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development
Published in Development (Cambridge) (01-12-2015)“…Lipid-containing alveolar interstitial fibroblasts (lipofibroblasts) are increasingly recognized as an important component of the epithelial stem cell niche in…”
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9
Origin and characterization of alpha smooth muscle actin‐positive cells during murine lung development
Published in Stem cells (Dayton, Ohio) (01-06-2017)“…ACTA2 expression identifies pulmonary airway and vascular smooth muscle cells (SMCs) as well as alveolar myofibroblasts (MYF). Mesenchymal progenitors…”
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10
Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis
Published in Cell reports (Cambridge) (05-04-2022)“…The lung alveolus is lined with alveolar type 1 (AT1) and type 2 (AT2) epithelial cells. During alveologenesis, increasing demand associated with expanding…”
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11
Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung
Published in American journal of physiology. Lung cellular and molecular physiology (15-01-2016)“…Distal lung epithelium is maintained by proliferation of alveolar type II (AT2) cells and, for some daughter AT2 cells, transdifferentiation into alveolar type…”
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12
Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia
Published in The Journal of pathology (01-01-2017)“…Inflammation‐induced FGF10 protein deficiency is associated with bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurely born infants…”
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13
The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement
Published in Molecular and Cellular Biology (01-04-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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14
Cell-specific expression of aquaporin-5 (Aqp5) in alveolar epithelium is directed by GATA6/Sp1 via histone acetylation
Published in Scientific reports (14-06-2017)“…Epigenetic regulation of differentiation-related genes is poorly understood. We previously reported that transcription factors GATA6 and Sp1 interact with and…”
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15
Overexpression of Fibroblast Growth Factor-10 during Both Inflammatory and Fibrotic Phases Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice
Published in American journal of respiratory and critical care medicine (01-09-2009)“…Fibroblast growth factor-10 (FGF10) controls survival, proliferation, and differentiation of distal-alveolar epithelial progenitor cells during lung…”
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16
A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis
Published in Frontiers in genetics (23-01-2019)“…This study demonstrates that FGF10/FGFR2b signaling on distal epithelial progenitor cells, via ß-catenin/EP300, controls, through a comprehensive set of…”
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17
Alteration of secretory leukocyte protease inhibitor in human myometrium during labor
Published in American journal of obstetrics and gynecology (01-03-2009)“…Objective Secretory leukocyte protease inhibitor (SLPI) has been shown to have antimicrobial and antiinflammatory properties. The aim of this study was to…”
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18
WNT5a-ROR Signaling Is Essential for Alveologenesis
Published in Cells (Basel, Switzerland) (07-02-2020)“…WNT5a is a mainly "non-canonical" WNT ligand whose dysregulation is observed in lung diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive…”
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19
Wnt5a Participates in Distal Lung Morphogenesis
Published in Developmental biology (01-08-2002)“…Operational parallels in overall mechanisms of three-dimensional patterning of vertebrate organs are becoming increasingly apparent. Many key mediators, such…”
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20
Signaling via Alk5 controls the ontogeny of lung Clara cells
Published in Development (Cambridge) (01-03-2010)“…Clara cells, together with ciliated and pulmonary neuroendocrine cells, make up the epithelium of the bronchioles along the conducting airways. Clara cells are…”
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