Search Results - "Parvez, Shabi"
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Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis
Published in Scientific reports (22-07-2020)“…The development of an effective oral therapeutics is an immediate need for the control and elimination of visceral leishmaniasis (VL). We exemplify the…”
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Recuperating Biopharmaceutical Aspects of Amphotericin B and Paromomycin Using a Chitosan Functionalized Nanocarrier via Oral Route for Enhanced Anti-leishmanial Activity
Published in Frontiers in cellular and infection microbiology (15-10-2020)“…The design and development of new pharmaceutical formulations for the existing anti-leishmanial is a new strategic alternate to improve efficacy and safety…”
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Fabrication, physicochemical characterization and In vitro anticancer activity of nerolidol encapsulated solid lipid nanoparticles in human colorectal cell line
Published in Colloids and surfaces, B, Biointerfaces (01-07-2022)“…Nerolidol is a sesquiterpene that occurs naturally and possesses a diverse set of biological characteristics including anticancer activity but has limited…”
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Transport mechanism of hydroxy-propyl-beta-cyclodextrin modified solid lipid nanoparticles across human epithelial cells for the oral absorption of antileishmanial drugs
Published in Biochimica et biophysica acta. General subjects (01-08-2022)“…In this study, the transport mechanism of fluorescently labeled hydroxypropyl beta-cyclodextrin (HPβ-CD) modified SLNs loaded with Amphotericin B (AmB) and…”
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Organ-restricted delivery through stimuli-responsive nanocarriers for lung cancer therapy
Published in Life sciences (1973) (01-12-2022)“…Lung Cancer (LC) is the malignant tumor of the lungs which is defined by the unrestricted cell development in the lung tissues which if left untreated may…”
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Folate receptor targeted NIR cleavable liposomal delivery system augment penetration and therapeutic efficacy in breast cancer
Published in Biochimica et biophysica acta. General subjects (01-09-2023)“…Liposomes are predominantly used sorts of nanocarriers for active a targeted delivery through surface functionalization using targeting ligand. The folate…”
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Effervescent based nano-gas carrier enhanced the bioavailability of poorly aqueous soluble drug: A comprehensive mechanistic understanding
Published in Journal of drug delivery science and technology (01-03-2022)“…The low aqueous solubility of drug molecules is a considerable hurdle to produce the desired pharmacological effect through any biological route of drug…”
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Nanoformulation mediated silencing of P-gp efflux protein for the efficient oral delivery of anti-leishmanial drugs
Published in Journal of drug delivery science and technology (01-12-2022)“…To enhance the physicochemical properties of a drug and to achieve targeting the development of transporter-based nanoformulations are receiving more attention…”
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Improvising anti-leishmanial activity of amphotericin B and paromomycin using co-delivery in d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) tailored nano-lipid carrier system
Published in Chemistry and physics of lipids (01-09-2020)“…•We aimed to design, develop and evaluate (in-vitro) a novel d-α-tocopheryl polyethylene glycol 1000 succinate modified amphotericin B (AmB) and paromomycin…”
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Coalition of Biological Agent (Melatonin) With Chemotherapeutic Agent (Amphotericin B) for Combating Visceral Leishmaniasis via Oral Administration of Modified Solid Lipid Nanoparticles
Published in ACS biomaterials science & engineering (12-06-2023)“…In this study, 2-hydroxypropyl-β-cyclodextrin (HPβCD) grafted solid lipid nanoparticle (SLN)-based bioconjugate was synthesized and used for administering a…”
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Sensible graphene oxide differentiates macrophages and Leishmania : a bio-nano interplay in attenuating intracellular parasite
Published in RSC advances (22-07-2020)“…is an obligate intracellular protozoan parasite, which resides in human macrophage vacuoles that are referred to as parasitophorus vacuoles. Amphotericin B…”
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Sensible graphene oxide differentiates macrophages and : a bio-nano interplay in attenuating intracellular parasite
Published in RSC advances (22-07-2020)“…Leishmania is an obligate intracellular protozoan parasite, which resides in human macrophage vacuoles that are referred to as parasitophorus vacuoles…”
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Formulation, characterization and in vitro anti-leishmanial evaluation of amphotericin B loaded solid lipid nanoparticles coated with vitamin B12-stearic acid conjugate
Published in Materials Science & Engineering C (01-12-2020)“…Despite the advancement of new anti-leishmanials, amphotericin B (AmB) prevails as one of the most potent agent in the treatment of visceral leishmaniasis…”
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Formulation, characterization and in vitro anti-leishmanial evaluation of amphotericin B loaded solid lipid nanoparticles coated with vitamin B 12 -stearic acid conjugate
Published in Materials science & engineering. C, Materials for biological applications (01-12-2020)“…Despite the advancement of new anti-leishmanials, amphotericin B (AmB) prevails as one of the most potent agent in the treatment of visceral leishmaniasis…”
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