Search Results - "Parussini, Fabiola"

Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii by Parussini, Fabiola, Coppens, Isabelle, Shah, Parag P, Diamond, Scott L, Carruthers, Vern B

“…Regulated exocytosis allows the timely delivery of proteins and other macromolecules precisely when they are needed to fulfil their functions. The…”
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Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication by Parussini, Fabiola, Tang, Qing, Moin, Syed M, Mital, Jeffrey, Urban, Sinisa, Ward, Gary E

“…Apical membrane antigen 1 (AMA1) is a conserved transmembrane adhesin of apicomplexan parasites that plays an important role in host-cell invasion. Toxoplasma…”
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Toxoplasma gondii Cathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl by Larson, Eric T., Parussini, Fabiola, Huynh, My-Hang, Giebel, Jonathan D., Kelley, Angela M., Zhang, Li, Bogyo, Matthew, Merritt, Ethan A., Carruthers, Vern B.

“…The protozoan parasite Toxoplasma gondii relies on post-translational modification, including proteolysis, of proteins required for recognition and invasion of…”
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Toxoplasma gondii transmembrane microneme proteins and their modular design by Sheiner, Lilach, Santos, Joana M, Klages, Natacha, Parussini, Fabiola, Jemmely, Noelle, Friedrich, Nikolas, Ward, Gary E, Soldati-Favre, Dominique

“…Host cell invasion by the Apicomplexa critically relies on regulated secretion of transmembrane micronemal proteins (TM-MICs). Toxoplasma gondii possesses…”
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A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complex by Harper, Jill M, Huynh, My-Hang, Coppens, Isabelle, Parussini, Fabiola, Moreno, Silvia, Carruthers, Vern B

“…Propeptides regulate protein function and trafficking in many eukaryotic systems and have emerged as important features of regulated secretory proteins in…”
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All Trypanosoma cruzi developmental forms present lysosome-related organelles by Sant’Anna, Celso, Parussini, Fabiola, Lourenço, Daniela, de Souza, Wanderley, Cazzulo, Juan Jose, Cunha-e-Silva, Narcisa Leal

“…Trypanosoma cruzi epimastigote forms concentrate their major protease, cruzipain, in the same compartment where these parasites store macromolecules obtained…”
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Two metallocarboxypeptidases from the protozoan Trypanosoma cruzi belong to the M32 family, found so far only in prokaryotes by Niemirowicz, Gabriela, Parussini, Fabiola, Agüero, Fernán, Cazzulo, Juan J

“…MCPs (metallocarboxypeptidases) of the M32 family of peptidases have been identified in a number of prokaryotic organisms, and only a few of them have been…”
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Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii: Cathepsin L in a vacuolar compartment by Parussini, Fabiola, Coppens, Isabelle, Shah, Parag P., Diamond, Scott L., Carruthers, Vern B.

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A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii by Brydges, Susannah D., Harper, Jill M., Parussini, Fabiola, Coppens, Isabelle, Carruthers, Vern B.

“…Background information. Accurate sorting of proteins to the three types of secretory granules in Toxoplasma gondii is crucial for successful cell invasion by…”
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Characterization of a lysosomal serine carboxypeptidase from Trypanosoma cruzi by Parussini, Fabiola, Garcı́a, Mayra, Mucci, Juan, Agüero, Fernán, Sánchez, Daniel, Hellman, Ulf, Åslund, Lena, Cazzulo, Juan José

“…Trypanosoma cruzi, the flagellate protozoan which is the causative agent of the American trypanosomiasis, Chagas disease has carboxypeptidase activity. The…”
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Expression in insect cells of active mature cruzipain from Trypanosoma cruzi, containing its C-terminal domain by Alvarez, Vanina, Parussini, Fabiola, Åslund, Lena, Cazzulo, Juan J

“…Cruzipain, the major cysteine proteinase from Trypanosoma cruzi, is a member of the papain family that contains a C-terminal domain in the mature enzyme, in…”
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