Search Results - "Partridge, L J"

Tetraspanins in viral infections : a fundamental role in viral biology? by MARTIN, F, ROTH, D. M, JANS, D. A, POUTON, C. W, PARTRIDGE, L. J, MONK, P. N, MOSELEY, G. W

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The emerging specialty of perioperative medicine: a UK survey of the attitudes and behaviours of anaesthetists by Partridge, J S L, Rogerson, A, Joughin, A L, Walker, D, Simon, J, Swart, M, Dhesi, J K

“…In 2014, the Royal College of Anaesthetists (RCoA) launched the Perioperative Medicine Programme to facilitate the delivery of best preoperative,…”
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Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review by Swarbrick, C J, Partridge, J S L

“…Delirium is one of the most commonly occurring postoperative complications in older adults. It occurs due to the vulnerability of cerebral functioning to…”
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Steady flows in a naturally-ventilated enclosure containing both a distributed and a localised source of buoyancy by Partridge, J.L., Linden, P.F.

“…We consider the flows and stratification established in a naturally-ventilated enclosure containing both localised and distributed sources of buoyancy. In this…”
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Randomized clinical trial of comprehensive geriatric assessment and optimization in vascular surgery by Partridge, J. S. L., Harari, D., Martin, F. C., Peacock, J. L., Bell, R., Mohammed, A., Dhesi, J. K.

“…Background Increasing numbers of older patients are undergoing vascular surgery. Inadequate preoperative assessment and optimization may contribute to…”
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Human Monoclonal Antibodies Against a Plethora of Viral Pathogens From Single Combinatorial Libraries by Williamson, R. Anthony, Burioni, Roberto, Sanna, Pietro P., Partridge, Lynda J., Barbas, Carlos F., Burton, Dennis R.

“…Conventional antibody generation usually requires active immunization with antigen immediately prior to the preparation procedure. Combinatorial antibody…”
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The impact of pre‐operative comprehensive geriatric assessment on postoperative outcomes in older patients undergoing scheduled surgery: a systematic review by Partridge, J. S. L., Harari, D., Martin, F. C., Dhesi, J. K.

“…Summary Comprehensive geriatric assessment is an established clinical approach. It reduces mortality and improves the physical wellbeing of older people in the…”
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The role of somatic mutation in determining the affinity of anti‐DNA antibodies by BEHRENDT, M., PARTRIDGE, L. J., GRIFFITHS, B., GOODFIELD, M., SNAITH, M., LINDSEY, N. J.

“…SUMMARY Combinatorial antibody libraries were constructed from the spleen of a patient with concomitant systemic lupus erythematosus and idiopathic…”
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The Fluxes and Behaviour of Plumes Inferred from Measurements of Coherent Structures within Images of the Bulk Flow by Burridge, H.C., Partridge, J.L., Linden, P.F.

“…This paper describes how measurements of the movement of identifiable features at the edge of a turbulent plume can be interpreted to determine the properties…”
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Toward Antibody-Directed ``Abzyme'' Prodrug Therapy, ADAPT: Carbamate Prodrug Activation by a Catalytic Antibody and its in vitro Application to Human Tumor Cell Killing by Wentworth, Paul, Datta, Anita, Blakey, David, Boyle, Tom, Partridge, Lynda J., Blackburn, G. Michael

“…Antibody-directed enzyme prodrug therapy, ADEPT, is a recent approach to targeted cancer chemotherapy intended to diminish the nonspecific toxicity associated…”
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Characterization of a complement-fragment-C5a-stimulated calcium-influx mechanism in U937 monocytic cells by MONK, P. N, PARTRIDGE, L. J

“…The mechanism by which complement fragment C5a elevates intracellular Ca2+ ([Ca2+]i) levels in two cell types, a monocytic cell line, U937, and neutrophils,…”
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A Foundation Programme educational placement in peri‐operative medicine for older people: mixed methods evaluation by Rogerson, A., Partridge, J. S. L., Dhesi, J. K.

“…Summary We established an innovative Foundation placement in peri‐operative medicine for older patients in response to the need for training in ‘whole patient’…”
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Localization of the binding site for the human high-affinity Fc receptor on IgG by Duncan, Alexander R, Woof, Jennifer M, Partridge, Lynda J, Burton, Dennis R, Winter, Greg

“…A major pathway in the clearance of pathogens involves the coating of the pathogen with specific antibodies, and the binding of the antibody Fc region to cell…”
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Preoperative assessment of the older patient by Pang, C.L., Gooneratne, M., Partridge, J.S.L.

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Production of catalytic antibodies using combinatorial libraries by Partridge, L J

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A Combinatorial Phage Display Library for the Generation of Specific Fab Fragments Recognizing Human Spermatozoa and Inhibiting Fertilizing Capacity In Vitro by CLAYTON, R, COOKE, I. D, PARTRIDGE, L. J, MOORE, H. D. M

“…To select a source of lymphocytes for the generation of an anti-sperm-biased combinatorial phage display library, venous blood was obtained from 34…”
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Antibody cross‐linking of human CD9 and the high‐affinity immunoglobulin E receptor stimulates secretion from transfected rat basophilic leukaemia cells by Higginbottom, A., Wilkinson, I., McCullough, B., Lanza, F., Azorsa, D. O., Partridge, L. J., Monk, P. N.

“…Summary Previous studies have shown that antibody cross‐linking of the tetraspanin protein CD9 stimulates the degranulation of platelets and eosinophils,…”
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Geriatricians in perioperative medicine: developing subspecialty training by Braude, P., Partridge, J.S.L., Hardwick, J., Shipway, D.J.H., Dhesi, J.K.

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Do Surgical Trainees Believe They Are Adequately Trained to Manage the Ageing Population? A UK Survey of Knowledge and Beliefs in Surgical Trainees by Shipway, D.J.H., BMBCh, Partridge, J.S.L., MBChB, Foxton, C.R., BMBCh, Modarai, B., PhD, Gossage, J.A., MS, Challacombe, B.J., MS, Marx, C., DL, Dhesi, J.K., PhD

“…Objective Increasing numbers of older patients are undergoing surgery. Older surgical patients are at a higher risk of perioperative complications and…”
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Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library by Blackburn, G Michael, Plückthun, Andreas, Cesaro-Tadic, Sandro, Lagos, Dimitrios, Honegger, Annemarie, Rickard, James H, Partridge, Lynda J

“…This report describes the selection of highly efficient antibody catalysts by combining chemical selection from a synthetic library with directed in vitro…”
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